Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach

Emmanuel, R.; Saravanan, Muthupandian; Ovais, Muhammad; Padmavathy, S.; Shinwari, Zabta Khan; Prakash, P.

doi:10.1016/j.micpath.2017.10.055

Cited by 103 publications

(48 citation statements)

References 47 publications

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“…This is due to the broad range of microorganisms that react in a different way with the metal ions for MtNP synthesis. Microbial MtNPs of different sizes and shapes have been reported in various species of bacteria, fungi and yeasts due to their enhanced growth rate, easy cultivation and their capability to grow under established conditions of temperature, pH and pressure [10,11]. The biosynthesis of MtNPs and their alloys (gold, silver, gold-silver alloy, selenium, tellurium, platinum, palladium, silica, titania, zirconia, quantum dots, magnetite and uraninite) has been reported in different microorganisms, including bacteria, actinomycetes, fungi, yeasts and viruses.…”

Section: Background and Role Of Microbial Enzymes In Metal Nanoparmentioning

confidence: 99%

Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach

Ovais

Khalil

Ayaz

et al. 2018

IJMS

Self Cite

352

171

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During the last decade, metal nanoparticles (MtNPs) have gained immense popularity due to their characteristic physicochemical properties, as well as containing antimicrobial, anti-cancer, catalyzing, optical, electronic and magnetic properties. Primarily, these MtNPs have been synthesized through different physical and chemical methods. However, these conventional methods have various drawbacks, such as high energy consumption, high cost and the involvement of toxic chemical substances. Microbial flora has provided an alternative platform for the biological synthesis of MtNPs in an eco-friendly and cost effective way. In this article we have focused on various microorganisms used for the synthesis of different MtNPs. We also have elaborated on the intracellular and extracellular mechanisms of MtNP synthesis in microorganisms, and have highlighted their advantages along with their challenges. Moreover, due to several advantages over chemically synthesized nanoparticles, the microbial MtNPs, with their exclusive and dynamic characteristics, can be used in different sectors like the agriculture, medicine, cosmetics and biotechnology industries in the near future.

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Section: Background and Role Of Microbial Enzymes In Metal Nanoparmentioning

confidence: 99%

Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach

Ovais

Khalil

Ayaz

et al. 2018

IJMS

Self Cite

352

171

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“…1. Biosynthesized NPs pave the way for diverse applications of nanotechnology Such "bionanofactories" are accessible to unique structures, are environmentally efficient, and have a high selective ability to absorb individual elements (Honary et al, 2012;Barabadi et al, 2017;Emmanuel et al, 2017). Compared to conventional approaches, biosynthetic NPs are better applied in different industries, in particular in drinking water treatment (Mekkawy et al, 2017;Patanjali et al, 2019).…”

Section: Characterization Of Nanoparticlesmentioning

confidence: 99%

Bacterial synthesis of nanoparticles: A green approach

et al. 2020

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In recent decades, the attention of scientists has been drawn towards nanoparticles (NPs) of metals and metalloids. Traditional methods for the manufacturing of NPs are now being extensively studied. However, disadvantages such as the use of toxic agents and high energy consumption associated with chemical and physical processes impede their continued use in various fields. In this article, we analyse the relevance of the use of living systems and their components for the development of "green" synthesis of nano-objects with exceptional properties and a wide range of applications. The use of nano-biotechnological methods for the synthesis of nanoparticles has the potential of large-scale application and high commercial potential. Bacteria are an extremely convenient target for green nanoparticle synthesis due to their variety and ability to adapt to different environmental conditions. Synthesis of nanoparticles by microorganisms can occur both intracellularly and extracellularly. It is known that individual bacteria are able to bind and concentrate dissolved metal ions and metalloids, thereby detoxifying their environment. There are various bacteria cellular components such as enzymes, proteins, peptides, pigments, which are involved in the formation of nanoparticles. Bio-intensive manufacturing of NPs is environmentally friendly and inexpensive and requires low energy consumption. Some biosynthetic NPs are used as heterogeneous catalysts for environmental restoration, exhibiting higher catalytic efficiency due to their stability and increased biocompatibility. Bacteria used as nanofactories can provide a new approach to the removal of metal or metalloid ions and the production of materials with unique properties. Although a wide range of NPs have been biosynthetic and their synthetic mechanisms have been proposed, some of these mechanisms are not known in detail. This review focuses on the synthesis and catalytic applications of NPs obtained using bacteria. Known mechanisms of bioreduction and prospects for the development of NPs for catalytic applications are discussed.

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“…Surface Plasmon Resonance (SPR) peaks attained in UV-Vis spectroscopy is one of the versatile techniques to confirm the formation of metal NPs and it was generated due to the coherence of electrons on the surface of AuNPs. The study of Emmanuel et al [11] demonstrated that the decrease in the conjugation length and intensities of AuNPs indicates the decrease in particle size. Hence, the CE + AuNPs conjugation length and intensities decreased from 595 to 544 nm which signifies the decrease in size.…”

Section: Characterization Of Ce + Aunps and Uv-visible Spectroscopy Amentioning

confidence: 99%

“…C. alata contains alquinone, 3,5,7,4-tetrahydroxy flavone and flavonoid glycosides [34]. The observed antibacterial effect of CE + AuNPs may be accounted to their reduced particle size enabling efficient delivery [11].…”

Section: Antibacterial Activity Of Plant Extracts Against Aeromonas Hmentioning

confidence: 99%

Ethnobotanical biosynthesis of gold nanoparticles and its downregulation of Quorum Sensing-linked AhyR gene in Aeromonas hydrophila

Fernando

Cruz

2020

SN Appl. Sci.

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This study highlights and combines the advantages of quorum sensing inhibition using scientifically untapped medicinal plants, the ethnobotanicals, through an effective drug delivery system, nanotechnology, to develop antivirulence drugs to control aquaculture pathogens. The ethnobotanical extracts and biologically synthesized gold nanoparticles of the Ilongot-Eǵongot community show antibacterial activity against gram-negative Aeromonas hydrophila. The ethnobotanical crude extracts (CEs) and crude extracts + gold nanoparticles (CEs + AuNPs) exhibit Quorum Sensing Inhibition activity through inhibition of the biofilm formation in A. hydrophila. Moreover, ethnobotanical CEs + AuNPs show much greater activity than its counterpart CEs in antibacterial and biofilm formation assay in A. hydrophila. Thus, this study supports the use of biological synthesis of gold nanoparticles to improved drug delivery which indicate the potential of these ethnobotanicals for therapeutic approach in inhibiting bacterial virulence without developing resistance.

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Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach

Cited by 103 publications

References 47 publications

Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach

Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach

Bacterial synthesis of nanoparticles: A green approach

Ethnobotanical biosynthesis of gold nanoparticles and its downregulation of Quorum Sensing-linked AhyR gene in Aeromonas hydrophila

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