Antimicrobial efficacy of medium chain fatty acids as root canal irrigants: An in vitro study

Devan, Krishnapriya; Peedikayil, Faizal C; Chandru, TP; Kottayi, Soni; Dhanesh, N.; Suresh, K.

doi:10.4103/jisppd.jisppd_63_19

Cited by 8 publications

(9 citation statements)

References 26 publications

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“…Antifungal activity of lauric acid also has been reported in several studies 45, 46, 52, 56, 57. Devan et al.…”

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 71%

“…Antifungal activity of lauric acid also has been reported in several studies [45,46,52,56,57]. Devan et al [52] reported that the antifungal activity of lauric acid against the growth of C. albicans was demonstrated by the MIC value of 0.4637 μg.…”

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 74%

“…In addition, a Log reduction assay was carried out on Helicobacter pylori and the result indicated that lauric acid reduced the growth by 1 mM for 1 h [53]. Lauric acid can also inhibit the growth of Enterococcus faecalis [52] with a maximum inhibition at 24 h with a MIC value of 2.5794 μg and Clostridium difficile as determined by a reduction in colony-forming units per milliliter [18].…”

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 99%

“…Devan et al. 52 reported that the antifungal activity of lauric acid against the growth of C. albicans was demonstrated by the MIC value of 0.4637 μg. The effectiveness of lauric acid on the inhibition of Aspergillus niger has also been investigated by Altieri et al 58 and the results showed that the inhibitory activity rises with the increasing minimum detection time (MDT) of 3.22 ± 0.34 days and lag times of 2.09 ± 0.70 days.…”

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 99%

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Antimicrobial Properties of Lauric Acid and Monolaurin in Virgin Coconut Oil: A Review

et al. 2022

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Virgin coconut oil is obtained by wet processing of coconut milk using fermentation, centrifugation, enzymatic extraction, and the microwave heating method. Presently, VCO has several positive effects and benefits to human health, hence, it is regularly consumed and widely known as a unique functional food. VCO contains lauric acid (45 to 52 %). By lipase in the digestive system, VCO can undergo a breakdown into lauric acid, 1-monolaurin, and 2-monolaurin. These components have both hydrophilic and lipophilic groups and are also recognized as excellent antimicrobial lipids. Furthermore, lauric acid and monolaurin can be used as antibacterial, antifungal, and antiviral with broad-spectrum inhibition. Lauric acid and monolaurin have a strong ability to destroy gram-positive bacteria, especially S. aureus, fungi such as C. Albicans, and viruses including vesicular stomatitis virus (VSV), herpes simplex virus (HSV), and visna virus (VV). Lauric acid and monolaurin interact with certain functional groups located in the cell membrane and can cause damage to the cell. In general, the potential of VCO as healthy food is contributed by lauric acid and monolaurin which are antimicrobial agents.

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“…Antifungal activity of lauric acid also has been reported in several studies 45, 46, 52, 56, 57. Devan et al.…”

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 71%

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 74%

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 99%

Section: Antimicrobial Activities Of Lauric Acidmentioning

confidence: 99%

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Antimicrobial Properties of Lauric Acid and Monolaurin in Virgin Coconut Oil: A Review

et al. 2022

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“…In the present study, coconut oil has shown antifungal activity that is comparable to that of ketoconazole. Previous studies have shown C. albicans to be highly susceptible to coconut oil [60], especially to the lauric acid of coconut oil [61].…”

Section: Virulence Markers Of Candida Speciesmentioning

confidence: 94%

Characterization and Virulence of Candida Isolated from Children with Dental Caries and Its Susceptibility to Various Antimicrobial Agents

Beena¹

2021

Dental Caries

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Candida is known to be associated with early colonization of cariogenic microorganisms leading to dental caries and there is a need to determine the effectiveness of various chemotherapeutic agents against it. The study is aimed to isolate, characterize Candida from the dental plaque of children with dental caries, to study its virulence factors and the antimicrobial activity of coconut oil, probiotics, 0.2% chlorhexidine and ketoconazole on C. albicans. Samples were collected using sterile cotton swabs from children with dental caries and streaked on Sabouraud's dextrose agar plates and incubated at 37°C for 24 h. Candidal colonies were isolated, species identified, and virulence factors tested, and its susceptibility to 0.2% chlorhexidine, probiotics, coconut oil, and ketoconazole was determined using disc diffusion method. C. albicans was the predominant species isolated, and virulence factors such as phospholipase, hemolysin, germ tube, and hyphal formation were seen. The mean zone of inhibition for chlorhexidine was found to be 21.8 mm, for coconut oil it was 16.8 mm, for probiotics it was 13.5 mm, and for ketoconazole it was 22.3 mm. The difference between the groups was not statistically significant. Thus chlorhexidine and coconut oil were found to exhibit significant antimicrobial activity which is comparable with ketoconazole.

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Chemical composition and antimicrobial potential of Acrocomia aculeata (Jacq.) Lodd. ex Mart. and Syagrus cearensis Noblick (Arecaceae)

Sampaio

Pereira

Coutinho

et al. 2023

Microbial Pathogenesis

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Antimicrobial efficacy of medium chain fatty acids as root canal irrigants: An in vitro study

Cited by 8 publications

References 26 publications

Antimicrobial Properties of Lauric Acid and Monolaurin in Virgin Coconut Oil: A Review

Antimicrobial Properties of Lauric Acid and Monolaurin in Virgin Coconut Oil: A Review

Characterization and Virulence of Candida Isolated from Children with Dental Caries and Its Susceptibility to Various Antimicrobial Agents

Chemical composition and antimicrobial potential of Acrocomia aculeata (Jacq.) Lodd. ex Mart. and Syagrus cearensis Noblick (Arecaceae)

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