Antimicrobial gallic acid from Caesalpinia mimosoides Lamk.

Chanwitheesuk, Anchana; Teerawutgulrag, Aphiwat; Kilburn, Jeremy D.; Rakariyatham, Nuansri

doi:10.1016/j.foodchem.2005.11.008

Cited by 228 publications

(147 citation statements)

References 15 publications

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“…The antimicrobial activity observed in the hydroethanolic extract and in the ethyl acetate fraction may be related to the presence of gallic acid. 14,15 Its presence in the alcoholic extract of Cesalpinea mimosoides, followed by its isolation as a single active compound, confirms the antimicrobial effect observed in this species.…”

Section: Resultssupporting

confidence: 55%

Phenolic derivatives and other chemical compounds from Cochlospermum regium

Solon¹,

Carollo²,

Brandão³

et al. 2012

Quím. Nova

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This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature

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Section: Resultssupporting

confidence: 55%

Phenolic derivatives and other chemical compounds from Cochlospermum regium

Solon¹,

Carollo²,

Brandão³

et al. 2012

Quím. Nova

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“…Several studies revealed that these phenolic compounds have some biological properties, such as anti-oxidant, anti-microbial and anti-cancer activities (Chanwitheesuk et al, 2007;Kim, 2007;Frampton et al, 2010;Lu et al, 2010;Daduang et al, 2011;Hahnvajanawong et al, 2011;Niknafs, 2011;Sakong et al, 2011;Kim and Lee, 2012). Caffeine is thought to increase the anti-tumor effect of cisplatin or DNA-damaging agents because caffeine inhibits DNA repair.…”

Section: 449 Cytotoxic Effects Of Phytophenolics From Caesalpinia MImentioning

confidence: 99%

“…Caesalpinia mimosoides Lamk is used as a fresh dietary vegetable indicating the possible safety of its future utilization. C mimosoides Lamk has been reported to exhibit anti-microbial (Chanwitheesuk et al, 2007) and anti-oxidant activities (Chanwitheesuk et al, 2005). Potential anti-inflammatory diterpenoids have been isolated from the roots of C mimosoides Lamk (Yodsaoue et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic Effects of Phytophenolics from Caesalpinia mimosoides Lamk on Cervical Carcinoma Cell Lines through an Apoptotic Pathway

Palasap¹,

Limpaiboon²,

Boonsiri³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…In another study, mace extracts showed antimicrobial action against several oral pathogens, in particular against S mutans, S mitins, and S salivarius, with an ethanol extract showing stronger activity than an ethyl acetate extract 4 Many plants polyphenolics have been reported to have an antimicrobial activity againts S. aereus. [15][16] Another important component that had antimicrobial activity could be sabinene, as has been reported previously. 17 The present study showed that ME and EAE can be further exploited as natural antibacterial agents.…”

Section: Antibacterial Activitymentioning

confidence: 67%

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

Simamora¹,

Santoso²,

Timotius³

2018

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Introduction: Myristica fragrans Houtt is used as a spice in Indonesia. This study aimed to scientifically validate the traditional use of mace from M. fragrans. Methods: The mace was extracted with methanol and ethyl acetate, and the chemical composition was analysed by GC-MS. The extracts were evaluated for their antibacterial activities against seven different bacteria based on a well diffusion method, their antioxidant activities based on DPPH radical scavenging assay, and their α-glucosidase inhibitory activities in vitro. Results: Four major components were identified from both extracts: sabinene, methoxyeugenol, myristicin, and elemicin. The methanol extract (ME) had higher methoxyeugenol, myristicin and elimisin levels, whereas sabinene was dominant in ethyl acetate extract (EAE). Both extracts showed good antibacterial activity against S. aureus only. Both extracts showed good antioxidant activities, in which EAE showed stronger activity than ME (IC 50 94 μg GAE/ml and IC 50 162 μg GAE/ml, respectively). Further more, both extracts inhibited α-glucosidase more strongly than the standard acarbose, in which ME (IC 50 7.50 μg GAE/ml) exhibited stronger α-glucosidase inhibitory capacity than EAE (IC 50 10.65 μg GAE/ml). Conclusion:The results suggest that ME and EAE of M. fragrans have biological activities with high potential for pharmacological uses.

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Antimicrobial gallic acid from Caesalpinia mimosoides Lamk.

Cited by 228 publications

References 15 publications

Phenolic derivatives and other chemical compounds from Cochlospermum regium

Phenolic derivatives and other chemical compounds from Cochlospermum regium

Cytotoxic Effects of Phytophenolics from Caesalpinia mimosoides Lamk on Cervical Carcinoma Cell Lines through an Apoptotic Pathway

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

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