2018
DOI: 10.1002/14651858.cd010597.pub2
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Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis

Abstract: Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis.

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Cited by 34 publications
(33 citation statements)
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References 78 publications
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“…63 The effectiveness of citrate and antimicrobial lock solutions in decreasing the rate of catheter-related infections remains unclear and is the subject of ongoing investigation. 64 In addition to the risk of bleeding from an inadvertent bolus of the locking solution with catheter access, all catheters will leak locking solution for the first 30 min with some systemic effects occurring for up to four hours. Heparin carries a further risk of heparin-induced thrombocytopenia, and citrate risks a metallic taste and perioral and/or digital paresthesia.…”
Section: Timing Of Rrtmentioning
confidence: 99%
“…63 The effectiveness of citrate and antimicrobial lock solutions in decreasing the rate of catheter-related infections remains unclear and is the subject of ongoing investigation. 64 In addition to the risk of bleeding from an inadvertent bolus of the locking solution with catheter access, all catheters will leak locking solution for the first 30 min with some systemic effects occurring for up to four hours. Heparin carries a further risk of heparin-induced thrombocytopenia, and citrate risks a metallic taste and perioral and/or digital paresthesia.…”
Section: Timing Of Rrtmentioning
confidence: 99%
“…Second, make better use and improve outcome of tCVC or implanted venous access port devices by implementing strict rules of handling and generalisation of catheter locking solutions [157].…”
Section: Va Future Outlookmentioning
confidence: 99%
“…The ESMO guidelines (2015) [18] and the recent literature [19], provide for the use of ALT in prevention for long-term infections associated with central venous catheters (CLABSI) in cancer patients. Even if several evidences support the use of ALT in seriously ill patients such as patients in need of palliative care, the effectiveness in patients in need of hemodialysis is still unclear [20]. Despite the elaboration of all these clinical practice protocols or guidelines, the most appropriate lock solution for central venous access devices is still to be defined [19].…”
Section: Introductionmentioning
confidence: 99%