Antimicrobial metal–organic frameworks incorporated into electrospun fibers

Antimicrobial electrospun silver-, copper- and zinc-doped polyvinylpyrrolidone nanofibers

“…Zinc, on the other hand, was predominantly as Zn 2+ with a minor contribution of ZnCl + , ( ) systematically lower values, a bias which is associated to the presence of significant amounts of viable but non-culturable microorganisms [32].…”

“…The incubation time for staining was 15 min at 25ºC. Details on the experimental setup and the surface mapping procedure can be found elsewhere[32].…”

Bioactive Applications for Electrospun Fibers

“…41 Besides nanometals, other materials can be used for the controlled release of antimicrobial metals. Quir os et al 42 prepared composite mats by electrospinning PLA with a suspension of PVP-stabilized Co-SIM-1 (cobalt-based substituted imidazolate). Co-SIM-1 belongs to the family of metal-organic frameworks (MOF), which is a class of hybrid materials in which organic bridging ligands are connected by metal ions to form three dimensional networks.…”

“…A load of 6 wt.% Co-SIM-1/PLA decreased the colonization of mats by P. putida by 40%. 42 Composite antibacterial mats can be prepared by including materials that impart specific surface physical properties to the nanofibers. Tourmaline (a silicate) decorated polyurethane (PU) composite nanofibers prepared as superhydrophilic antibacterial material.…”

Antibacterial electrospun chitosan-polyethylene oxide nanocomposite mats containing ZIF-8 nanoparticles

“…Recently, a novel biocompatible, bioactive and antibacterial MOF was synthesized and it was shown that it was stable in water and in bacterial culture medium leading to its subsequent progressive release [28]. Antibacterial activities of composite electrospun mats containing cobalt-based MOFs were assessed with Pseudomonas putida and Staphylococcus aureus [29] for which up to 60% reduction in the number of colony forming microorganisms were observed.…”