Antimicrobial nanotechnology: research implications and prospects in food safety

Srividya, N.; Ghoora, Manjula D.; Padmanabh, Pushkala R.

doi:10.1016/b978-0-12-804303-5.00004-3

Cited by 14 publications

(6 citation statements)

References 129 publications

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“…One way to overcome the challenges posed by antibiotics is using nanotechnology. Many types of nanoparticles, such as polymeric micelles, biodegradable polymeric nanoparticles, fullerenes, nanocapsules, nanogels, nanoliposomes, solid lipid nanoparticles, metal nanoparticles and dendrimers, have been used as drug delivery systems [ 177 ].…”

Section: Biomedical Applications Of Dendrimersmentioning

confidence: 99%

Applications and Limitations of Dendrimers in Biomedicine

et al. 2020

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Biomedicine represents one of the main study areas for dendrimers, which have proven to be valuable both in diagnostics and therapy, due to their capacity for improving solubility, absorption, bioavailability and targeted distribution. Molecular cytotoxicity constitutes a limiting characteristic, especially for cationic and higher-generation dendrimers. Antineoplastic research of dendrimers has been widely developed, and several types of poly(amidoamine) and poly(propylene imine) dendrimer complexes with doxorubicin, paclitaxel, imatinib, sunitinib, cisplatin, melphalan and methotrexate have shown an improvement in comparison with the drug molecule alone. The anti-inflammatory therapy focused on dendrimer complexes of ibuprofen, indomethacin, piroxicam, ketoprofen and diflunisal. In the context of the development of antibiotic-resistant bacterial strains, dendrimer complexes of fluoroquinolones, macrolides, beta-lactamines and aminoglycosides have shown promising effects. Regarding antiviral therapy, studies have been performed to develop dendrimer conjugates with tenofovir, maraviroc, zidovudine, oseltamivir and acyclovir, among others. Furthermore, cardiovascular therapy has strongly addressed dendrimers. Employed in imaging diagnostics, dendrimers reduce the dosage required to obtain images, thus improving the efficiency of radioisotopes. Dendrimers are macromolecular structures with multiple advantages that can suffer modifications depending on the chemical nature of the drug that has to be transported. The results obtained so far encourage the pursuit of new studies.

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Section: Biomedical Applications Of Dendrimersmentioning

confidence: 99%

Applications and Limitations of Dendrimers in Biomedicine

et al. 2020

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“…Therefore, antimicrobial compounds have been used to prevent or eliminate microbial contamination (Speranza et al, 2017). There are several compounds that exhibit antimicrobial activity, such as metal ions and their oxides (e.g., silver, copper, zinc, magnesium, palladium and titanium) or natural antimicrobial agents (e.g., essential oils, bacteriocins, among others) (Srividya et al, 2017). However, these compounds are chemically reactive species that can originate undesirable effects when incorporated into a food matrix like beverages, causing alterations on the physical stability or integrity of the food product, as well as a reduction in the biological activity of antimicrobials.…”

Section: Removal Of Chemicals or Pathogensmentioning

confidence: 99%

“…The bioactivity of nanosystems is dependent on multiple factors, including the particle size, shape, concentration, charge and sensitivity of microorganism to nanosystem action (Srividya et al, 2017). The antimicrobial effect is size-dependent, for instance Panáček et al (2006) showed that the action of silver nanoparticles raised with the decrease of the nanoparticle diameter, which is likely due to a larger surface area of interaction that improves the binding capacity to the microbial cell (Panáček et al, 2006).…”

Section: Removal Of Chemicals or Pathogensmentioning

confidence: 99%

A Step Forward on Micro- and Nanotechnology in Beverage Industry

Silva

Borges

Freixo

et al. 2020

Nanoengineering in the Beverage Industry

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“…Hence, the continuous exploration for effective antimicrobial and preservative agents in food industries has resulted in the emergence and application of bio-nanotechnology (Zorraquín-Peña et al, 2020). Bio-nanotechnology is now an evolving option that can be employed to enhance food bio-functionality, maintain food nutrients and prevent the growth of microorganisms associated with food borne diseases (Srividya et al, 2017 andBajpai et al, 2018). Degradable bio-polymers combined with nanoparticles could serve as prospective substitutes to conventional antibiotics because of their antimicrobial activities, since they are readily available, simple to prepare, safe, cost effective and eco-friendly.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Silver Nanoparticles using Cellulose and Starch Extracted from Brewer Spent Grain: Assessment of their Antimicrobial and Preservatives Activities

Ogidi¹,

Emmanuel²,

Daramola³

et al. 2023

Turkish JAF Sci.Tech.

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Non-porous materials like cellulose and starch can be extracted from agro- industrial wastes and incorporated with nanoparticles for effective biotechnological purposes. In this study, silver nanoparticles (AgNps), silver-cellulose nanoparticles (AgNps-C) and silver-starch nanoparticles (AgNps-S) were characterized by UV-visible spectroscopy. Fourier transform infrared spectroscopy (FTIR) was used to identify viable biomolecules involved in capping and active stabilization of AgNps. Average sizes and morphologies of AgNps, AgNps-C and AgNps-S were further analyzed by scanning electron microscopy (SEM) and the percentage composition of each element was investigated by energy-dispersive X-ray spectroscopy (EDS). Antimicrobial activity of the synthesized AgNPs-C and AgNPs-S was tested against multiple antibiotic resistance microorganisms isolated from fish and meat. Zones of inhibition displayed by AgNPs-C and AgNPs-S ranged from 8.00 to 13.30 mm and 5.00 to 10.30 mm, respectively. The Minimum inhibitory concentration (MIC) for AgNPs-C and AgNPS-S ranged from 125 µg/mL to 500 µg/mL and 500 µg/mL to 1000 µg/mL, respectively. AgNPS-S and AgNPs-C inhibited the growth of microorganisms associated with spoilage of fish and meat. The bio-applications of AgNP –C and AgNP-S can be exploited in food industries as preservative agent or incorporated to packaging materials to elongate the shelf life of food products and reduce the side effects attributed to chemical preservative agents.

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Antimicrobial nanotechnology: research implications and prospects in food safety

Cited by 14 publications

References 129 publications

Applications and Limitations of Dendrimers in Biomedicine

Applications and Limitations of Dendrimers in Biomedicine

A Step Forward on Micro- and Nanotechnology in Beverage Industry

Synthesis of Silver Nanoparticles using Cellulose and Starch Extracted from Brewer Spent Grain: Assessment of their Antimicrobial and Preservatives Activities

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