Antimicrobial Peptides: New Frontiers in the Therapy of Infections

Zucca, Mario; Scutera, Sara; Savoia, Dianella

doi:10.5772/29323

Drug Development - A Case Study Based Insight Into Modern Strategies 2011

DOI: 10.5772/29323

|View full text |Cite

Antimicrobial Peptides: New Frontiers in the Therapy of Infections

Mario Zucca¹,

Sara Scutera²,

Dianella Savoia³

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2013

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

References 202 publications

(160 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Novel avenues forClostridium difficileinfection drug discovery

Zucca

Scutera²,

Savoia

2013

Expert Opinion on Drug Discovery

Self Cite

View full text Add to dashboard Cite

Beyond the development of new antibiotics, virulence-targeting factors or phage cocktails seem promising strategies, which could replace antibiotics avoiding the emergence of resistant strains and the onset of C. difficile infection (CDI). Until broad-spectrum antimicrobials will be in use, C. difficile-specific lytic phages could help to prevent CDI by eliminating C. difficile in patients and in the hospital staff, and for the prevention and treatment of recurrences. Phage therapy is not currently available in Western countries, but, in our opinion, it should have a new chance. Fecal therapy is emerging as a very effective and readily available treatment for recurrences. The shift is from a standardized, drug-based antibacterial therapy toward the forthcoming less expensive and nonpatentable procedures of a more personalized medicine. This will imply profound changes affecting both patient-physician interactions and the current profit-oriented approach to the pharmacologic therapy of infections.

show abstract

Novel avenues forClostridium difficileinfection drug discovery

Zucca

Scutera²,

Savoia

2013

Expert Opinion on Drug Discovery

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Antimicrobial Peptides: New Frontiers in the Therapy of Infections

Cited by 1 publication

References 202 publications

Novel avenues forClostridium difficileinfection drug discovery

Novel avenues forClostridium difficileinfection drug discovery

Contact Info

Product

Resources

About