Antimicrobial Potential of Tuber Part of the Traditional Medicinal Climber, Solena Amplexicaulis (Lam.) Gandhi. Against Certain Human

Abstract

The present study was made to evaluate the in vitro antimicrobial activity minimum inhibitory concentration of Solena amplexicaulis tuber extracts [hexane, benzene, chloroform, methanol and water] against 15 bacterial and 9 fungal species and to determine the minimum inhibitory concentration (MIC) for its methanolic extract against the human pathogens. In vitro antimicrobial activity was determined by using agar disc diffusion technique and MIC was determined by using broth dilution method. The results of the study revealed that the chloroform extract showed highest degree of antimicrobial activity against all the microbes tested than the other extracts. The MIC exhibited by methanolic tuber extract against the tested organisms was ranging between 300 and 600μg/mL for bacterial species and between 300 and 500μg/mL for fungal species. S. amplexicaulis tuber extracts especially chloroform extract inhibits the growth of all human pathogens.

Antioxidant, antimicrobial, toxicity and analgesic properties of ethanol extract of Solena amplexicaulis root

“…Even though the extracts were not as strong Fe 2+ chelators as EDTA, the investigated extract demonstrated notable chelating properties. Ferrous ion chelating activity of SAET was close to the results of Karthika et al [17]. Metal chelating capacity was significant as they reduced the concentration of catalyzing transition metal in lipid peroxidation.…”

“…This situation forced the researchers to search for new anti-microbial substance from various sources including medicinal plant [24]. Karthika and Paulsamy [17] reported that S. Amplexicaulis extracts of leaf and stem exhibited antibacterial and anti-fungal activity. The findings revealed that medicinal plant Solena amplexicaulis can play a vital role in combating fungal resistance.…”

“…In Bangladesh this species is found in Chittagong, Chittagong Hill Tracts, [15]. Except anti-inflammatory activity [16] antioxidant [12] and antibacterial [17] of Solena amplexicaulis there is no published work on the pharmacological effect of root extracts of the plant. The previous studies were done with leaf and stem or the whole plant .…”

Evaluation of Anti-inflammatory and Antioxidant Properties of Crude Extract and Forskolin from Solena amplexicaulis Leaf

“…Based on use value, information consensus factor and fidelity level, Venkatachalapathi et al [11] reported that it is one among the five most important species in the treatment of inflammation and wound healing in Nilgiris of Western Ghats being prescribed by the Irula tribal community. In addition to this, it is known from the literature that the tubers are astringent, appetizer, carminative, cardiotonic, digestive, diuretic, expectorant, invigorating, purgative, stimulant, sour and thermogenic [12] .Our early laboratory data also recorded several therapeutic properties as antimicrobial [13] and antioxidant activities [14] and phytochemical constituents [15,16] for this species. Terpenoids, the characteristic feature of the family, Cucurbitaceae [17,18] are attributed to various pharmacological claims including antiinflammatory, anticancer, antimalarial, antiviral and antibacterial activities [19] .…”

PENENTUAN PROFIL KROMATOGRAFI LAPIS TIPIS, KADAR FENOLIK TOTAL, DAN AKTIVITAS ANTIOKSIDAN DARI EKSTRAK DAUN GEDI (Abelmochus manihot L.)

“…Untuk pemisahan metabolit sekunder yang ada di ekstrak daun gedi, ekstrak ditotolkam secara manual menggunakan pipa kapiler pada pelat silika gel GF254 dengan ukuran 10x5 cm, tebal 3 mm. Pelat yang telah ditotoli sampel dimasukkan ke dalam bejana yang sudah berisi fase gerak sesuai dengan metode Karthika et al, (2014)…”