Antimicrobial Profile of Premna pubescens. Blume and Centella asiatica Extracts Against Bacteria and Fungi Pathogens

Restuati, Martina; Diningrat, Diky Setya

doi:10.3923/ijp.2018.271.275

Cited by 11 publications

(8 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the antioxidant and antibacterial activity test, the experimental data were calculated as mean ± SEM, evaluated by unpaired One-way ANOVA. Test values of p < 0.01 were considered statistically significant (Diningrat et al, 2020;Restuati and Diningrat, 2018).…”

Section: Discussionmentioning

confidence: 99%

“…Standard disc of Ciprofloxacin (5 μg/disc) and blank discs (impregnated with solvents followed by evaporation) were used as the positive and negative control, respectively. The antimicrobial activity of the test agents was determined by measuring the diameter of the zone of inhibition expressed in mm (Al-Shuneigat et al, 2015;Diningrat et al, 2020;Restuati and Diningrat, 2018).…”

Section: Antibacterial Activitymentioning

confidence: 99%

See 1 more Smart Citation

Antioxidant and antibacterial activities of Coix lacryma-jobi seed and root oil potential for meningitis treatment

2021

JJBS

View full text Add to dashboard Cite

Bacterial meningitis is a dreaded infectious disease in the human pulmonary system caused by bacterial invasion and promoting inflammation. Hanjeli (Coix lacryma-jobi) seed and root oil have antioxidant, anti-inflammatory, and antibacterial properties that can be used in the treatment of bacterial meningitis. The study aims to investigate the potential of oil from C. lacryma-jobi seed and root part for bacterial meningitis treatment. The phytochemical screening was performed using standard protocols. Antibacterial activity and minimum inhibitory concentration (MIC) were conducted by the disc diffusion and two-fold dilution method. The preliminary phytochemical screening of C. lacryma-jobi shows that essential oil of root and seed part contains steroids, carotenoids, tannins, alkaloid salts, reducing compounds, flavonoid, anthracenoid, coumarin derivatives, cardenoid, anthocyanins, and saponins. The determination of total phenolic, tannin contents, and antioxidant in essential oil from the root was significantly higher (p <0.05) than the seed part. The C. lacrymajobi oil from both parts expressed the highest antimicrobial activity against Streptococcus pneumoniae and Klebsiella pneumoniae. Additionally, the lowest minimum inhibitory concentration (12.5-50 mg/mL) was observed against selected bacteria of meningitis. It is concluded that oil from C. lacryma-jobi root and seed parts contains compounds that might be used in the bacterial meningitis treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Antibacterial Activitymentioning

confidence: 99%

Antioxidant and antibacterial activities of Coix lacryma-jobi seed and root oil potential for meningitis treatment

2021

JJBS

View full text Add to dashboard Cite

show abstract

“…Extracts of different parts of plants contain bioactive compounds, such as alkaloids, steroids, tannins, glycosides, volatile oils, fixed oils, resins, phenols, terpenoids, and flavonoids that fight against diseases [ 18 ]. The phenolic phytochemicals from plants play a key role as antimicrobial agents [ 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Assessing the Efficiency of Antimicrobial Plant Extracts from Artemisia afra and Eucalyptus globulus as Coatings for Textiles

Nortjie,

Basitere,

Moyo

et al. 2024

Plants

View full text Add to dashboard Cite

This study aimed to assess the antimicrobial activities of plant extracts from Artemisia afra and Eucalyptus globulus when used as coatings for textiles. A pulsed ultrasound-assisted extraction method (PUAE) was employed to obtain methanolic and hexanoic extracts from both plants. Eucalyptus globulus methanol extraction exhibited the highest yield at 22.76% (±0.61%), while Artemisia afra demonstrated lower yields. Phytochemical screening identified various secondary metabolites in the extracts, including phenols, quinones, and steroids. Antimicrobial tests against Staphylococcus aureus and Escherichia coli revealed varying degrees of susceptibility, with Eucalyptus globulus hexanoic extracts showing the highest activity against Staphylococcus aureus at an average percentage growth of 18.74% (±0.26%). Minimum inhibitory concentration (MIC) values were determined for the extracts, but complete inhibition did not occur at concentrations below 500 μg/mL. The extracts exhibited varying effects on Staphylococcus aureus and Escherichia coli growth, with some extracts promoting bacterial growth. Coating textiles with Eucalyptus globulus methanolic extracts demonstrated antibacterial activity against Staphylococcus aureus with the highest zone of inhibition observed in cotton-coated samples (258.4 mm2). Polyester-coated samples exhibited smaller inhibition zones, with the lowest observed in Eucalyptus globulus methanolic extract coating (65.97 mm2). Scanning electron microscope (SEM) analysis revealed visible surface morphology changes in coated fabrics, depicting fine, cluster, lumpy, flaky, and fragment-like morphologies. Laundering effects on coated fabrics were investigated, showing a significant decrease in antimicrobial activity after washing. Fourier-transform infrared spectroscopy (FTIR) identified functional groups in the extracts associated with antimicrobial properties. The complexity of the bioactive compounds suggests potential antimicrobial efficacy, resting on factors such as geographical location, climate, and extraction methods. Notwithstanding the limitations, this study contributes valuable insights into the use of plant extracts as antimicrobial coatings for textiles.

show abstract

“…Biological screening, separation of the phytochemicals, and clinical trials of the medicinal plants have advanced over the years unfolding the secrets of ancient herbal remedies [ 3 ]. Traditional medicine is effective in dealing with diseases caused by bacteria or oxidative stress [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Natural compounds have been extensively explored for new drug discoveries [ 7 ] Humanity has always been fascinated by natural compounds from pre-biotic, microbial, plant, and animal sources. Extracts of different parts of plants contain bioactive compounds that fight against diseases such as alkaloids, steroids, tannins, glycosides, volatile oils, fixed oils, resins, phenols, terpenoids, and flavonoids [ 8 ] The phenolic phytochemicals from plants play a key role as antimicrobial agents [ 6 , 9 ] Antimicrobial agents decay the protein components of the cell wall, disrupting the work of enzymes and DNA and RNA replication [ 10 ] Table 1 shows a selection of plants, their phytochemicals responsible for antimicrobial activity, and their applications.…”

Section: Introductionmentioning

confidence: 99%

Extraction Methods, Quantitative and Qualitative Phytochemical Screening of Medicinal Plants for Antimicrobial Textiles: A Review

Nortjie

Basitere

Moyo³

et al. 2022

Plants

View full text Add to dashboard Cite

Medicinal plants are the product of natural drug discoveries and have gained traction due to their pharmacological activities. Pathogens are everywhere, and they thrive in ideal conditions depending on the nutrients, moisture, temperature, and pH that increase the growth of harmful pathogens on surfaces and textiles. Thus, antimicrobial agents and finishes may be the solution to the destruction of pathogens. This review article presents an analysis of various aspects of producing antimicrobial finishings, the microorganisms, their mechanism of attachment to natural and synthetic fibre, the effect of microbial growth, and the principle and mechanism of the microbial activity of the medicinal plants. Furthermore, the extraction methods, qualitative and quantitative phytochemical evaluations of antimicrobial efficacy, and developments of antimicrobial treated textiles using various agents are covered in this review.

show abstract

Antimicrobial Profile of Premna pubescens. Blume and Centella asiatica Extracts Against Bacteria and Fungi Pathogens

Cited by 11 publications

References 12 publications

Antioxidant and antibacterial activities of Coix lacryma-jobi seed and root oil potential for meningitis treatment

Antioxidant and antibacterial activities of Coix lacryma-jobi seed and root oil potential for meningitis treatment

Assessing the Efficiency of Antimicrobial Plant Extracts from Artemisia afra and Eucalyptus globulus as Coatings for Textiles

Extraction Methods, Quantitative and Qualitative Phytochemical Screening of Medicinal Plants for Antimicrobial Textiles: A Review

Contact Info

Product

Resources

About