Antimicrobial Properties of Metal Nanoparticles and Their Oxide Materials and Their Applications in Oral Biology

Abstract

Some scholars have shown that metal nanoparticles have excellent antibacterial properties and can be used as a new type of antibacterial agent. In recent years, with the in-depth research on nanomaterials, its applications in the medical field have gradually increased. The oral cavity has a unique anatomical structure, and for oral infections, the current clinically commonly used treatment measures are oral or topical antibiotics. However, due to bacterial resistance and the special structure of dental plaque, the effect of antibiotics is not ideal. Metal and metal oxide nanoparticles have become the research hotspot of new antibacterial materials due to their small particles, large specific surface area, physical, mechanical, and chemical properties, and antibacterial properties. This article describes the antibacterial effect, antibacterial mechanism, biological toxicity, and application progress of metal nanomaterials in the oral cavity.

Biosynthesis of TiO2 nanoparticles by Caricaceae (Papaya) shell extracts for antifungal application

“…Titanium dioxide Nanoparticles have received significant consideration because of their exceptional antibacterial, antifungal, UV-filtering characteristics, extraordinary catalytic as well as photochemical activities 30 , 31 . Fabrications of titanium dioxide nanoparticles are often luxurious, and methods used in the procedure need high energies 32 . Additionally, poisonous diluters and poisonous chemicals are used in these approaches.…”

Green synthesis of M-type manganese-substituted strontium hexaferrite SrMnxFe12−xO19 nanoparticles with intrinsic antibacterial activity against human pathogenic bacteria

“…Numerous MONPs, including SFs and HFs with well-established antibacterial activity, have been reported as possible antimicrobial agents over the last few years. 12,13,32 SFs and HFs are used to remove organic dyes, 16 herbicides, 33 pesticides, 34 and medicines. 33,35,36 Similarly, they were used for water purification, 26 cancer hyperthermia treatment, 37 cytotoxic chemotherapy, 21 drug delivery, 21,38 and detecting biomolecules with catalase peroxidase enzyme mimetic activity.…”

“…8,9 Therefore, extensive recent research has focused on the exploration of new and efficient antibacterial substances, such as nanoparticles composed of metals (MNPs) and metal oxides (MONPs). [10][11][12] The therapeutic efficacy of MONPs in many biomedical applications has received worldwide attention, 13 due to their special physical and chemical characteristics, such as high bioavailability, excessive reactive oxygen species (ROS), and vital oxidative stress (OS). 14,15 Green-based synthesis of MNPs and MONPs has gained significant attention because it overcomes many environmental concerns raised by traditional chemical-based synthesis methods.…”

Recent advances in metal nanoparticles to treat periodontitis

“…To do their part, metal NPs eliminate the biofilm. An essential contributor to the resurgence of drug-resistant bacteria that has resulted in a dramatic rise in mortality and morbidity and a drawn-out treatment cycle is the development of biofilms [ 47 , 48 ]. Furthermore, the metal ions released by these NPs kill bacterial DNA and protein.…”