Antimicrobial relevance of Cu (II) complexes of thiophene-2-glyoxal-p-halogen substituted anils

Abstract

Isomeric complexes of, p-chloro, p-bromo, and p-iodo -anils of 2-thiophene glyoxal ligands have been synthesized and characterized by metal analysis, molecular weight, infrared and UVVisible spectroscopy, molar conductance and magnetic measurements. All non electrolytic complexes are square planar paramagnetics. Among all of the compounds only p-bromo and p-iodo-anils of 2-thiophene glyoxal exhibited good antifungal activity against both test fungi but all products showed moderate to good bactericidal effect against S.aures and X.holicicola bacteria.