Antimicrobial resistance: a priority for global health action

Chioro, Arthur; Coll-Seck, Awa Marie; Høie, Bent; Moeloek, Nila F.; Motsoaledi, Aaron; Rajatanavin, Rajata; Touraine, Marisol

doi:10.2471/blt.15.158998

Cited by 37 publications

(28 citation statements)

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“…Es por ello que se considera relevante la información que aquí se presenta porque permite conocer la tendencia en la resistencia antimicrobana de aislados de sangre de un hospital de pacientes adultos con cáncer. 7,8 En los resultados obtenidos se observó que E. coli fue el patógeno más frecuentemente aislado en hemocultivos en todos los pacientes (figura 2) y que existe una tendencia creciente del aislamiento de E. coli BLEE, Velázquez-Acosta C y col.…”

Section: Discussionunclassified

Cepas E-ESKAPE multidrogorresistentes aisladas en hemocultivos de pacientes con cáncer

2018

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Objetivo. Describir la tendencia de cepas multidrogorresistentes (MDR) aisladas en hemocultivos de pacientes con cáncer durante el periodo de 2005 a 2015. Material y métodos. Análisis retrospectivo en el que se procesaron 33 127 hemocultivos. La identificación y la sensibilidad antimicrobianas se realizaron a través de métodos automatizados WaLK away (Siemens Laboratory Diagnostics) y BD Phoenix (Becton, Dickinson and Company). Se determinaron cepas resistentes de acuerdo con la concentración mínima inhibitoria, según los parámetros del Clinical and Laboratory Standards Institute (CLSI). Resultados. 5 604 (16.9%) aislamientos fueron positivos, con 6 397 aislamientos, 3 732 (58.4%) bacilos gramnegativos, 2 355 (36.9%) cocos grampositivos, 179 (2.7%) levaduras y 126 (1.9%) bacilos grampositivos. Escherichia coli (n=1 591, 24.5%) fue la bacteria más frecuente, 652 (41%) productoras de beta-lactamasas de espectro-extendido (BLEE); Enterococcus faecium 143 (2.1%), 45 (31.5%) resistente a vancomicina; Staphylococcus aureus 571 (8.7%), 121 (21.2%) resistentes a meticilina (SARM); Klebsiella pneumoniae 367 (5.6%), 41 (11.2%) BLEE, Acinetobacter baumannii 96 (1.4%), 23 (24%) MDR; Pseudomonas aeruginosa 384 (5.6%), 43 (11.2%) MDR. Las cepas MDR se aislaron más frecuentemente en pacientes con neoplasias hematológicas en comparación con tumores sólidos; SARM (RM=4.48, IC95% 2.9-6.8); E. coli BLEE (RM=1.3, IC95% 1.10-1.65) y A. baumannii-MDR (RM=3.2, IC95% 1.2-8.3). Conclusiones. Se observó un aislamiento significativamente mayor de cepas E-ESKAPE MDR en pacientes con neoplasias hematológicas.

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Section: Discussionunclassified

Cepas E-ESKAPE multidrogorresistentes aisladas en hemocultivos de pacientes con cáncer

2018

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“…Some estimates affirm that antibiotic use in animals is at least 1000‐fold greater in terms of absolute tonnage compared with the use in humans (World Health Organization , Chioro et al . , Lekshmi et al . ).…”

Section: Discussionmentioning

confidence: 99%

Antibiotic prescription for endodontic infections: a survey of Brazilian Endodontists

et al. 2017

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“…Antimicrobial Resistance (AMR) is a major global concern, negatively impacting public health outcomes (1)(2)(3)(4)(5), patient safety (3,(6)(7)(8) and poses enormous burden on economic development and security (8)(9)(10)(11)(12)(13)(14)(15)(16). Internationally, data suggests, at any given time, approximately one-third of the hospitalized patients and over two-thirds of critically ill patients are prescribed antimicrobials and more than half of these prescribed antimicrobials are deemed inappropriate (5,17,18).…”

Section: Introductionmentioning

confidence: 99%

Clinical and Economic Impact of Antimicrobial Stewardship Interventions Reported Among Hospital Inpatients in The Middle East: a Systematic Review Protocol

Thomas

Abdulrouf

Elkassem

et al. 2020

Preprint

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Antimicrobial Resistance (AMR) is a major global concern, negatively impacting public health outcomes (1-5), patient safety (3,6-8) and poses enormous burden on economic development and security (8-16). Internationally, data suggests, at any given time, approximately one-third of the hospitalized patients and over two-thirds of critically ill patients are prescribed antimicrobials and more than half of these prescribed antimicrobials are deemed inappropriate (5,17,18).

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Antimicrobial resistance: a priority for global health action

Cited by 37 publications

References 2 publications

Cepas E-ESKAPE multidrogorresistentes aisladas en hemocultivos de pacientes con cáncer

Cepas E-ESKAPE multidrogorresistentes aisladas en hemocultivos de pacientes con cáncer

Antibiotic prescription for endodontic infections: a survey of Brazilian Endodontists

Clinical and Economic Impact of Antimicrobial Stewardship Interventions Reported Among Hospital Inpatients in The Middle East: a Systematic Review Protocol

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