Antimicrobial resistance profiles of bacterial pathogens isolated from the bloodstream in patients of a hospital institution in Montería — Córdoba

Diaz-Cornejo, Nohra

doi:10.17485/ijst/v13i19.349

Cited by 1 publication

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References 31 publications

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“…It has been observed that delaying therapy initiation by an hour can result in an average decrease in survival of 8% [ 12 ]. In addition, when patients in the ICU with septicemia are administered inadequate empirical treatment, their mortality rates double from 30% to 60% [ 13 ]. The current study had a 31.8% culture-positive rate.…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Observational Study of the Microbial Etiology and Antimicrobial Susceptibility Patterns of Blood Cultures From ICU Patients at a Healthcare Facility in North India

Kumar,

Raj,

Singh

et al. 2024

Cureus

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Introduction Bloodstream infections (BSI) are a leading source of fatalities and morbidity in hospitals. However, the clinical spectrum and antimicrobial resistance differ globally. Identifying the pathogenic spectrum and variations in antibiotic resistance is crucial for controlling BSI and preventing inappropriate antibiotic use. Material and methods This retrospective observational study was conducted at the Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India, for one year between June 2022 and June 2023. A total of 669 adult patients' blood cultures were obtained from ICUs. Blood culture was done using a BacT/Alert 3D (BioMérieux SA, Marcy-l'Étoile, France) automated system. Identification of the bacterial as well as fungal isolates was done using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS), and the antimicrobial susceptibility profile was analyzed using the VITEK 2 Compact system (BioMérieux SA). Results Of the 669 blood culture samples, 213 (31.8%) showed bacterial or fungal growth. Of these 213 isolates, the most common isolate was coagulase-negative Staphylococci (21.6%), followed by Klebsiella pneumoniae (19.3%) and Acinetobacter spp. (17.8%). The majority of gram-negative bacteria were resistant to most drugs, and vancomycin and linezolid were both effective against the majority of gram-positive bacteria. Conclusion The current study found that septicemia was more frequently caused by gram-negative bacteria than by gram-positive bacteria. Blood cultures are always necessary in cases of suspected septicemia, and once the antimicrobial susceptibility profile of the pathogen causing septicemia has been determined, suitable antimicrobials should be prescribed and used to lower the antimicrobial resistance burden.

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Section: Discussionmentioning

confidence: 99%

A Retrospective Observational Study of the Microbial Etiology and Antimicrobial Susceptibility Patterns of Blood Cultures From ICU Patients at a Healthcare Facility in North India

Kumar,

Raj,

Singh

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

Antimicrobial resistance profiles of bacterial pathogens isolated from the bloodstream in patients of a hospital institution in Montería — Córdoba

Abstract: Barbera N (2020) Antimicrobial resistance profiles of bacterial pathogens isolated from the bloodstream in patients of a hospital institution in Montería-Córdoba.

Cited by 1 publication

References 31 publications

A Retrospective Observational Study of the Microbial Etiology and Antimicrobial Susceptibility Patterns of Blood Cultures From ICU Patients at a Healthcare Facility in North India

A Retrospective Observational Study of the Microbial Etiology and Antimicrobial Susceptibility Patterns of Blood Cultures From ICU Patients at a Healthcare Facility in North India

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