Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

Abstract

Introduction: Biologically potent compounds are one of the most important classes of materials for the upcoming generations. Increasing number of microbial infectious diseases and resistant pathogens create a demand and urgency to develop novel, potent, safe and improved variety of antimicrobial agents. This initiates a task for current chemistry to synthesize compounds that show promising activity as therapeutic agents with lower toxicity. Therefore, a substantial research is needed for their discovery and improvement. Chemistry of present era aims to build a pollution free environment. For the same, it targets to create some alternativeswhich are eco-friendly and nature loving. Present research work is a step towards achieving such alternatives. Method: For this the metallic soaps of copper (derived from common edible oils) were synthesized. The synthesized copper soaps have been confirmed by elemental analysis, UV, and IR spectroscopic technique. The fungicidal activities of copper soaps derived from soyabean, sesame oils have been evaluated by testing against Alternaria alternate and Aspergillus niger by P.D.A. technique. Result: The fungi toxicity results indicate that the strain of fungal species are susceptible towards these soaps and suggests that with the increase in concentration of copper soap it may increase further. The transition metallic soaps showed good antifungal activity because chelation increases the anti-microbial potency.

Synthesis and Evaluation of Copper Oleate Nanoparticles Against Citrus Anthracnose Caused by Colletotrichum gloeosporioides: In Situ Experiments, In Vitro Bioassays, and Field Trials

“…[43] Copper (II) soaps at concentration ranging from 1 to 10 mg/mL were also reported to moderately inhibit the mycelial growth of Alternaria alternata and Aspergillus niger in vitro. [15] The previous in vitro data in partly supported our findings of antifungal potent of copper (II) oleate. Howevere, our study was the first investigation of the antifungal activity of Cu-oleate@CS NPs against C. gloeosporioides.…”

“…However, this leads to a cause of higher toxicity and high risks compared to copper ions in inorganic salts. [7,[11][12][13][14][15] Many published patents focused on preparation of organic copper compounds to minimize environmental impact. For example, forms of organic copper compounds were discribed in patents EP2123161 A3 on "Product for agricultural use based on organic copper complexes" and US3323987A on "Fungicidal preparations containing copper bis-valerianate".…”

A Review on the Transition and Inner Transition Metallic Soaps

“…The effectiveness of lauric acid and copper carboxylates as bactericides, herbicides, and fungicides were discussed by Y. Yamamoto et.al [69] . R. Bhutra et.al [70] characterized copper formates derived from soybean and sesame oil by P.D.A. technique.…”

Synthesis, Characterization and Biological Analysis of Some Novel Complexes of Phenyl Thiourea Derivatives with Copper

“…This work also coincided with Sharma et al [33], Mathur et al [34], Bhutra el al. [35] on fungicidal activities of copper surfactants derived from lauric acid, substituted complex of benzothiazole of copper palmitic acid and copper surfactants derived from fried oils treated and untreated at higher temperatures, respectively.…”