Antimicrobial susceptibility of microorganisms that cause urinary tract infections in pediatric patients

Rodrı́guez-Lozano, Jesús; Malet, Ana de; Cano, María Eliecer; Rubia, Luis de la; Wallmann, Reinhard; Martı́nez-Martı́nez, Luis; Calvo, J.H.

doi:10.1016/j.eimce.2017.08.016

Cited by 8 publications

(4 citation statements)

References 21 publications

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“…In previous studies, P. aeruginosa was reported to be highly resistant to trimethoprimsulfamethoxazole, nitrofurantoin, cefotaxime, ampicillin, amoxicillin/clavulanate, cephalexin, cefuroxime, ceftriaxone, nalidixic acid 38,39 and more sensitive to piperacillin-tazobactam, ceftazidime, imipenem, ciprofloxacin, gentamicin, and tobramycin. 40 It is different with gram-positive bacteria, which show high sensitivity to vancomycin and linezolid with varying resistance patterns. Both of E. faecalis and E. faecium showed resistance Open access under CC-BY-NC-SA Share Alike 4.0 to ceftriaxone, trimethoprim-sulfamethoxazole, gentamicin, cefotaxime, amikacin, ciprofloxacin for about more than 70%, and sensitive to vancomycin, linezolid, teicoplanin.…”

Section: Discussionmentioning

confidence: 99%

Bacterial Profile and Antibiotic Resistance Pattern among Children with Urinary Tract Infections in Dr. Soetomo Hospital, Surabaya, Indonesia

Adhima

Wahyunitisari

Prasetyo

et al. 2022

IJTID

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Urinary tract infections (UTIs) are the most common infections in pediatric patients characterized by the growth of bacteria in the urine in significant numbers. Antibiotics remain the primary treatment of UTI in children. However, there has been an increase in antibiotic resistance to uropathogens worldwide due to their inappropriate and extensive uses. There is considerable geographical variation in the distribution of bacteria and antibiotic resistance pattern. Thus, to prevent further resistance and provide empirical antibiotic options, this study aims to determine the profile of bacteria and antibiotics resistance pattern among UTI pediatric patients in Dr. Soetomo Hospital. This study was performed by collecting data from the urine culture logbook at the Clinical Microbiology Laboratory of Dr. Soetomo Hospital in July-October 2019. The sample was UTI patients aged one day – 18 years due to bacterial infection with a colony count of ≥100,000 CFU/ml. In this study, 131 patients showed significant bacterial growth dominated by males and ages one month – 2 years. UTI were caused by gram-negative bacteria (74%) and gram-positive bacteria (26%), with the most bacteria found in each group were Escherichia coli and Enterococcus faecalis. E. coli showed ≥70% resistance to ampicillin, cefazoline, piperacillin, tetracycline, and trimethoprim-sulfamethoxazole. Comorbidities were dominated by hydronephrosis (10.98%), chronic kidney disease (9.79%) and hydrocephalus (8.09%). In conclusion, gram-negative bacteria were the leading cause of UTI in children with E. coli as the most common uropathogen, highly resistant to ampicillin and cefazolin. Gram-positive bacteria were less frequent with varied resistance patterns. Most common comorbidity was hydronephrosis.

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Section: Discussionmentioning

confidence: 99%

Bacterial Profile and Antibiotic Resistance Pattern among Children with Urinary Tract Infections in Dr. Soetomo Hospital, Surabaya, Indonesia

Adhima

Wahyunitisari

Prasetyo

et al. 2022

IJTID

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“…Microbiological analyses of pathogens causing UTI in children still indicate broad susceptibility to second-and third-generation cephalosporins, carbapenems, amikacin, gentamicin and ciprofloxacin, although in recent years there has been rapidly growing resistance to fluoroquinolones and a higher incidence of bacteria resistant to amoxicillin/clavulanic acid and β-lactamase-producing bacteria (extended spectrum beta-lactamases, ESBLs) (13) . The choice of antibiotic should therefore be based on local susceptibility profiles of bacterial flora (36,37,44,45) . Children…”

Section: Targeted Treatmentmentioning

confidence: 99%

Urinary tract infections in children in the era of growing antimicrobial resistance – recommendations of the Polish Society of Paediatric Nephrology

Zagożdżon,

Jung,

Kiliś-Pstrusińska

et al. 2023

Pediatr Med Rodz

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Introduction and objective: Urinary tract infections can recur in children, and due to their potential long-term consequences, they require appropriate diagnosis and prompt treatment. Although Escherichia coli is the most common aetiology, an increase in infections with drug-resistant strains has been observed. The aim of this study was to develop current diagnostic and treatment recommendations in the era of increasing microbial resistance. Materials and methods: The recommendations are based on updated guidelines developed by the experts of the Polish Society of Paediatric Nephrology and a literature review. Results: Because the symptoms of urinary tract infection are often non-specific, urinalysis and urine culture should be performed in children presenting with fever without an identifiable cause. Correct method of urine collection and interpretation of the results are crucial for therapeutic decisions. Treatment should be continued for 7–14 days for upper and 3–5 days for lower urinary tract infections; the choice of the narrowest-spectrum antimicrobial should be based on bacterial susceptibility. Antibiotic prophylaxis is limited and recommended in children with grade III–V vesicoureteral reflux. Non-pharmacological management should include treatment of bladder and bowel dysfunction. Ultrasound is recommended for all children up to 24 months of age. Indications for voiding cystourethrography are limited to cases with ultrasound abnormalities, recurrent and septic infections. Conclusion: The paper provides up-to-date, practical recommendations for the diagnosis and management of urinary tract infections in children in the era of increasing microbial resistance and restricted indications for invasive radiological investigations.

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“…Apesar da relevância do tema, Boon et al (2021) advertem que no atendimento ambulatorial, mais de metade das ITUs em crianças pode não ser detectada no primeiro contato, podendo culminar em possíveis complicações. Segundo Rodríguez-Lozano (2017), devido às possíveis complicações que podem levar à internação hospitalar de longa duração, sobretudo em crianças, como cicatrizes renais, hipertensão ou doença crônica, as ITUs se constituem num importante problema de saúde pública.…”

Section: Introductionunclassified

Caracterização Do Contexto E Dos Cuidados De Enfermagem À Pessoa Em Situação Crítica Em Serviços De Medicina Intensiva

Simões¹,

Martins²,

Magalhães³

et al. 2022

Enfermagem: Investigação Científica, Ensino E Assistência

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Direitos para esta edição cedidos à Atena Editora pelos autores. Open access publication by Atena Editora Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Antimicrobial susceptibility of microorganisms that cause urinary tract infections in pediatric patients

Cited by 8 publications

References 21 publications

Bacterial Profile and Antibiotic Resistance Pattern among Children with Urinary Tract Infections in Dr. Soetomo Hospital, Surabaya, Indonesia

Bacterial Profile and Antibiotic Resistance Pattern among Children with Urinary Tract Infections in Dr. Soetomo Hospital, Surabaya, Indonesia

Urinary tract infections in children in the era of growing antimicrobial resistance – recommendations of the Polish Society of Paediatric Nephrology

Caracterização Do Contexto E Dos Cuidados De Enfermagem À Pessoa Em Situação Crítica Em Serviços De Medicina Intensiva

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