Antimicrobial Susceptibility Pattern of Salmonella enterica Species in Blood Culture Isolates

Poudel, Sunil

doi:10.4172/2327-5073.1000141

Cited by 4 publications

(4 citation statements)

References 15 publications

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“…A very important finding in the present study is the reemergence of chloramphenicol from the amphenicol class of antibiotics [31,32], with a higher inhibitory activity than those currently applied to treat the disease. This agrees with the findings of Adabara et al [3] in Nigeria, Poudel et al [9] and Raza et al [33] both in Nepal. Also, Islam et al [34] reported in a study conducted in Bangladesh that only 28 (32.5%) out of 86 S. typhi isolates showed resistance to chloramphenicol, suggesting more susceptibility than resistance.…”

Section: Discussionsupporting

confidence: 93%

“…Previously, traditional regimens applied to treat enteric fever included chloramphenicol, ampicillin, and trimethoprim-sulfamethoxazole but the rise in multidrug-resistant (MDR) salmonellae around the mid to late 1990s brought about the use of fluoroquinolones such as ciprofloxacin, in the treatment of infections caused by salmonellae [7]. Resistance by Salmonella typhi (S. typhi) to antibiotics such as ciprofloxacin, ampicillin, ceftriaxone, cotrimoxazole and others, has increased lately [8][9][10]. This trend has heightened the difficulties faced in managing and treating the disease in adults and infants [1,11].…”

Section: Introductionmentioning

confidence: 99%

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Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Adikwu

Ogbonna

Obande

et al. 2022

Microbes and Infectious Diseases

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Adikwu

Ogbonna

Obande

et al. 2022

Microbes and Infectious Diseases

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“…Among studies examining Salmonella spp. (S. Typhi and S. Paratyphi) resistance rates in bacteremia isolates between 2012 and 2017, the rate of ciprofloxacin non-susceptibility ranged from 25% to 94% (126)(127)(128)(129)(130)(131)(132)(133)(134)(135). A limited number of studies examined the resistance rates of other organisms isolated from blood cultures (132)(133)(134)(135)(136).…”

Section: Nepalmentioning

confidence: 99%

Antimicrobial Resistance Surveillance in Low- and Middle-Income Countries: Progress and Challenges in Eight South Asian and Southeast Asian Countries

Alvarez-Uria²,

et al. 2020

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SUMMARY Antimicrobial resistance (AMR) is a serious global health threat and is predicted to cause significant health and economic impacts, particularly in low- and middle-income countries (LMICs). AMR surveillance is critical in LMICs due to high burden of bacterial infections; however, conducting AMR surveillance in resource-limited settings is constrained by poorly functioning health systems, scarce financial resources, and lack of skilled personnel. In 2015, the United Nations World Health Assembly endorsed the World Health Organization’s Global Action Plan to tackle AMR; thus, several countries are striving to improve their AMR surveillance capacity, including making significant investments and establishing and expanding surveillance networks. Initial data generated from AMR surveillance networks in LMICs suggest the high prevalence of resistance, but these data exhibit several shortcomings, such as a lack of representativeness, lack of standardized laboratory practices, and underutilization of microbiology services. Despite significant progress, AMR surveillance networks in LMICs face several challenges in expansion and sustainability due to limited financial resources and technical capacity. This review summarizes the existing health infrastructure affecting the establishment of AMR surveillance programs, the burden of bacterial infections demonstrating the need for AMR surveillance, and current progress and challenges in AMR surveillance efforts in eight South and Southeast Asian countries.

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“…Salmonella is a foremost food borne pathogen, responsible for an estimated 98.3 million cases of gastroenteritis worldwide 6 . This organism has frequently been associated with poultry 7 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2016

IJPSR

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Background: Widespread use of antibiotics in livestock production in large-scale across the globe has become of public and veterinary health importance because of its implication in antibiotic resistance. Adequate data in this area of research is not readily available in Nigeria; this study was undertaken in view of the possible link between antimicrobial resistance in farm animals and humans. Methods: We collected fifty samples of raw beef from different vendors and slaughter houses within Abuja and screened them for the presence of Listeria monocytogenes and Salmonella typhimurium using standard microbiological methods. The total bacterial and fungal counts, susceptibility of the isolates to different antibiotics and heat sensitivity at 55, 60 and 65ºC for 15 minutes were determined. Results: Our results show that ten isolates of Listeria monocytogenes and eighteen isolates of Salmonella typhimurium were isolated from the samples. The total viable bacteria count range was 1x 10 9 -8x 10 9 cfu/g while the fungal count was 1x 10 3 -9x 10 9 cfu/g. One (10 %) of the Listeria monocytogenes isolates was resistant to all antibiotics tested while all the Listeria monocytogenes isolates were resistant to cefuroxime. Eight (44.4%) of the Salmonella typhimurium isolates were resistant to at least three antibiotics. All the Listeria monocytogenes and Salmonella typhimurium isolates did not survive beyond 60 o C upon heat treatment. Conclusions: Our results indicate high prevalence of Salmonella typhimurium and Listeria monocytogenes in selected beef in Abuja. Beef therefore may represent a large reservoir for antimicrobial-resistant Salmonella typhimurium and Listeria monocytogenes.

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Antimicrobial Susceptibility Pattern of Salmonella enterica Species in Blood Culture Isolates

Cited by 4 publications

References 15 publications

Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Chloramphenicol is re-emerging as an effective drug in the treatment of typhoid fever in Southern Benue state, Nigeria

Antimicrobial Resistance Surveillance in Low- and Middle-Income Countries: Progress and Challenges in Eight South Asian and Southeast Asian Countries

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