2020
DOI: 10.1186/s13756-020-0684-2
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Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016

Abstract: Background: Antimicrobial resistance is a growing threat to the world's ability to prevent and treat infections. Links between quantitative antibiotic use and the emergence of bacterial resistance are well documented. This study presents benchmark antimicrobial use (AMU) rates for inpatient adult populations in acute-care hospitals across Canada. Methods: In this retrospective surveillance study, acute-care adult hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP) submitte… Show more

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Cited by 13 publications
(16 citation statements)
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“…The consumption of carbapenems and colistin was high and higher than in other hospitals, as well as previous studies in the same study site [56,57]. In general, the DDDs found were higher than those in developed countries [58][59][60].…”
Section: Discussionsupporting
confidence: 79%
“…The consumption of carbapenems and colistin was high and higher than in other hospitals, as well as previous studies in the same study site [56,57]. In general, the DDDs found were higher than those in developed countries [58][59][60].…”
Section: Discussionsupporting
confidence: 79%
“…15 Our data indicate that piperacillin-tazobactam is being used more frequently than cefazolin than it was previously. 6 We observed a general continuation in the order of most used antimicrobials between 2016 and 2018 in Canada. A major decrease in fluoroquinolone use was previously observed in Canadian hospitals that are part of the CNISP network.…”
Section: Discussionmentioning
confidence: 73%
“…The high prevalence of CACDI has raised many questions about the organism's origin. The gene sequence of human C. difficile has also been detected in strains isolated from different nonhospital sources, but there is currently no objective evidence of this source of human transmission (10). To better understand CACDI, it would be interesting to examine the studies related to its occurrence.…”
mentioning
confidence: 99%