Antimicrobial use-related drug therapy problems and associated factors among patients in the medical ward of Wachemo University Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Southwest Ethiopia

Adere, Arega; Edao, Amin; Tesfaye, M.; Petros, Zelalem

doi:10.1177/20503121221140228

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…Similar to our study, unnecessary drug treatment (32.8%) and the need for additional drug treatment (28.1%) were the most prevalent antimicrobial use-related problems in a study in south west Ethiopia. 27 Unnecessary antimicrobial was prescribed for 17% of patients in southwest Ethiopia, which is comparable with our finding. 2 …”

Section: Discussionsupporting

confidence: 90%

Antimicrobial Use-Related Problems Among Hospitalized Pediatric Patients: A Prospective Observational Study

Gidey,

Aregawi,

Hailu

et al. 2024

IDR

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Introduction Antimicrobials are among the most commonly misused medications, leading to antimicrobial resistance, and therefore demand more attention. There are limited studies documenting “antimicrobial use-related problems” in developing countries, especially in pediatric patients. Objectives This study aimed to evaluate the prevalence of antimicrobial use-related problems and risk factors among hospitalized pediatric patients. Materials and Methods A hospital-based prospective observational study was conducted in Ayder comprehensive specialized hospital (ACSH) in the Tigray region, Ethiopia. The participants of the study were pediatric patients aged ≤15 years who were admitted with a diagnosis of infectious disease between September 2019 and November 2019. Results A total of 232 pediatric patients were included in the study. Of these, 59.5% of the patients were male and the mean age (SD) of the patients was 5.8 (5.2) years. Of the 232 patients surveyed, a total of 177 antimicrobial use-related problems were identified. One or more antimicrobial use-related problems have occurred in more than half of the patients (53.9%). The commonest antimicrobial use problems were unnecessary antimicrobial therapy (22.8%) followed by need additional antimicrobial therapy (16.4%). In a multivariate logistic regression model, patients with comorbidities (Adjusted odds ratio (AOR): 1.84, 95% confidence interval (CI): 1.04–3.27) and hospital stays exceeding one week (AOR=1.88, 95% CI: 1.08–3.26) were predictors of antimicrobial use-related problems. Conclusion Antimicrobial use-related problems were found in a significant proportion of pediatric patients. Addressing these issues necessitates collaborative efforts, emphasizing targeted education, strengthened antimicrobial stewardship, ensuring responsible antimicrobial use and enhancing pediatric care.

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Section: Discussionsupporting

confidence: 90%

Antimicrobial Use-Related Problems Among Hospitalized Pediatric Patients: A Prospective Observational Study

Gidey,

Aregawi,

Hailu

et al. 2024

IDR

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Knowledge, attitudes, and practices toward preventing and controlling hepatitis B virus infection among pregnant women attending antenatal care at a University Hospital in Central Ethiopia: a cross-sectional study

Larebo,

Anshebo,

Behera

et al. 2024

Therapeutic Advances in Infection

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Background: Ethiopia is a country with a high endemicity of the hepatitis B virus, and the primary mode of transmission for this virus is mother-to-child transmission. However, the country lacks a comprehensive plan for viral hepatitis surveillance, prevention, and control. Objectives: To assess the knowledge, attitudes, and practices toward preventing and controlling hepatitis B virus infection among pregnant women attending antenatal care at a University Hospital in Central Ethiopia. Design: A hospital-based cross-sectional study was conducted among pregnant women from October to November 2023 at a University Hospital in Central Ethiopia. Methods: A total of 412 pregnant women were selected and included in the study using a systematic random sampling technique. An interviewer-administered questionnaire was used to collect the data. The collected data were imported into Epi-data version 3.1 and then exported to the Statistical Package for Social Sciences version 25 for analysis. In the bivariate analysis, variables with a p-value less than 0.25 were included in the multivariate analysis. A logistic regression model was used. A p-value <0.05 indicated statistical significance. Results: The overall response rate was 94.1%. Of the total 412 respondents, 37.6% exhibited good practices. Notably, pregnant women within the age categories of 29–39 years (adjusted odds ratio (AOR): 0.31; 95% confidence interval (CI): 0.15, 0.64) and ⩾40 years (AOR: 0.17; 95% CI: 0.06, 0.50), residing in rural areas (AOR: 0.35; 95% CI: 0.17, 0.70), with smaller family sizes (AOR: 0.13; 95% CI: 0.07, 0.25), lacking information about hepatitis B virus infection (AOR: 5.15; 95% CI: 2.91, 9.13), having a positive attitude (AOR: 0.03; 95% CI: 0.02, 0.06), and possessing good knowledge (AOR: 0.38; 95% CI: 0.20, 0.71) were significantly associated with poor practice. Conclusion: This study revealed that pregnant women had a low level of knowledge, attitudes, and practices related to hepatitis B virus infection prevention and control. A greater understanding is necessary to effectively prevent and control the spread of infection through prioritized health education programs targeting pregnant women. These programs must focus on raising awareness through campaigns that promote knowledge and immunization for their children.

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Antimicrobial use-related drug therapy problems and associated factors among patients in the medical ward of Wachemo University Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Southwest Ethiopia

Cited by 2 publications

References 27 publications

Antimicrobial Use-Related Problems Among Hospitalized Pediatric Patients: A Prospective Observational Study

Antimicrobial Use-Related Problems Among Hospitalized Pediatric Patients: A Prospective Observational Study

Knowledge, attitudes, and practices toward preventing and controlling hepatitis B virus infection among pregnant women attending antenatal care at a University Hospital in Central Ethiopia: a cross-sectional study

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