Antimicrobials in Food

Davidson, P. Michael; Taylor, T. Matthew; David, Jairus R. D.

doi:10.1201/9780429058196

Cited by 51 publications

(43 citation statements)

References 619 publications

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“…In relation to the studied multilayers, on a molecular level, a number of 'defects' likely exist between the loops and chains of the polysaccharides. The inclusion of the nisin Z within the films may impart regions of hydrophobicity, where certain regions of the nisin peptide (specifically across the N-terminal) contain hydrophobic residues 58 . Although the receding water contact angle measurements showed no differences in macroscopic surface hydrophobicity, the scale at which these hydrophobic regions exist within the multilayer may not have affected the wettability of the uppermost surface.…”

Section: Resultsmentioning

confidence: 99%

Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers

Webber

Namivandi-Zangeneh

Drozdek

et al. 2021

Sci Rep

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An antimicrobial peptide, nisin Z, was embedded within polyelectrolyte multilayers (PEMs) composed of natural polysaccharides in order to explore the potential of forming a multilayer with antimicrobial properties. Using attenuated total reflection Fourier transform infrared spectroscopy (ATR FTIR), the formation of carrageenan/chitosan multilayers and the inclusion of nisin Z in two different configurations was investigated. Approximately 0.89 µg cm−2 nisin Z was contained within a 4.5 bilayer film. The antimicrobial properties of these films were also investigated. The peptide containing films were able to kill over 90% and 99% of planktonic and biofilm cells, respectively, against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) strains compared to control films. Additionally, surface topography and wettability studies using atomic force microscopy (AFM) and the captive bubble technique revealed that surface roughness and hydrophobicity was similar for both nisin containing multilayers. This suggests that the antimicrobial efficacy of the peptide is unaffected by its location within the multilayer. Overall, these results demonstrate the potential to embed and protect natural antimicrobials within a multilayer to create functionalised coatings that may be desired by industry, such as in the food, biomaterials, and pharmaceutical industry sectors.

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Section: Resultsmentioning

confidence: 99%

Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers

Webber

Namivandi-Zangeneh

Drozdek

et al. 2021

Sci Rep

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“…Ability to invade the gut epithelium cells (Davidson et al, 2005) Limited reduction of C. jejuni under in-vitro settings (Davidson et al, 2005) Moreover, evisceration is one of the most critical steps of crosscontamination. Colonized gastrointestinal tract of poultry birds carries a large number of Campylobacter bacteria that can spread in a wide range, especially in the case of gut leakage.…”

Section: Short Chain Fatty Acidsmentioning

confidence: 99%

“…These plants are the main natural sources of cinnamon. Cinnamon oil consists of several major antimicrobial compounds, including cinnamaldehyde (70-90%), 1-linalool, p-cymene, and eugenol (Davidson et al, 2005). Aldehyde groups are reactive organic compounds that can crosslink covalently with proteins and nucleic acids through amine groups.…”

Section: Plant-based Antimicrobialsmentioning

confidence: 99%

Survival and Control of Campylobacter in Poultry Production Environment

Hakeem

2021

Front. Cell. Infect. Microbiol.

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Campylobacter species are Gram-negative, motile, and non–spore-forming bacteria with a unique helical shape that changes to filamentous or coccoid as an adaptive response to environmental stresses. The relatively small genome (1.6 Mbp) of Campylobacter with unique cellular and molecular physiology is only understood to a limited extent. The overall strict requirement of this fastidious microorganism to be either isolated or cultivated in the laboratory settings make itself to appear as a weak survivor and/or an easy target to be inactivated in the surrounding environment of poultry farms, such as soil, water source, dust, surfaces and air. The survival of this obligate microaerobic bacterium from poultry farms to slaughterhouses and the final poultry products indicates that Campylobacter has several adaptive responses and/or environmental niches throughout the poultry production chain. Many of these adaptive responses remain puzzles. No single control method is yet known to fully address Campylobacter contamination in the poultry industry and new intervention strategies are required. The aim of this review article is to discuss the transmission, survival, and adaptation of Campylobacter species in the poultry production environments. Some approved and novel control methods against Campylobacter species throughout the poultry production chain will also be discussed.

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“…Menurut Deshpande (2002) LD 50 asam asetat peroral pada mencit sebesar 4960 mg/kgBB. Sehingga didapatkan LD 50 asam asetat pada mencit 20 gram sebesar 99,2 mg. Menurut Davidson et al (2005) LD 50 asam asetat peroral pada tikus sebesar 3310 mg/kgBB. Sehingga didapatkan LD 50 asam asetat pada mencit 20 gram sebesar 92,68 mg. Berdasarkan sumber tersebut, pemberian cuka apel dosis 1 mL masih dibawah LD 50.…”

Section: δGdpunclassified

Reduction of Blood Glucose Levels by Apple Vinegar in Mice Induced by Dexamethasone

Rachmansyah

Junaidi²,

Effendi³

2020

AMS

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The number of people with diabetes mellitus (DM) in the world is 425 million in 2017. The use of antidiabetic drugs usually lasts long enough with high side effects. Therefore, an alternative treatment with lower side effects and the efficacy same with synthetic drugs is needed. One of alternative treatment is apple fruit which can be processed into apple vinegar. Several studies have found the hypoglycemic effect of apple cider vinegar in various dosages. The author wants to know the reduction of blood glucose levels and the effective dose of apple vinegar in reducing blood glucose levels in mice induced by dexamethasone. The type of research is true experimental laboratories with pre and post-test with control group design. This study used 28 mice. Mice were given dexamethasone for 10 days to induce hyperglycemia. After experiencing hyperglycemia, mice were divided into 7 groups consisting of negative control group, positive control group, and treatment group of 0.0625 mL apple cider vinegar, 0.125 mL, 0.25 mL, 0.5 mL, and 1 mL. The research data obtained ΔGDP in each group. Furthermore, the reduction in glucose levels is calculated. Effective dose calculation by regression analysis using percentage reduction of blood glucose levels curve. The final results showed the maximum effective dose of apple vinegar in reducing blood glucose levels is 0.341 mL with percentage reduction of blood glucose levels is 18.6%.

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Antimicrobials in Food

Cited by 51 publications

References 619 publications

Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers

Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers

Survival and Control of Campylobacter in Poultry Production Environment

Reduction of Blood Glucose Levels by Apple Vinegar in Mice Induced by Dexamethasone

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