Antimutagenic and antioxidant activity of Lisosan G in Saccharomyces cerevisiae

Frassinetti, Stefania; Croce, C. Della; Caltavuturo, Leonardo; Longo, Vincenzo

doi:10.1016/j.foodchem.2012.06.090

Cited by 30 publications

(23 citation statements)

References 29 publications

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“…Scientific reports show that total antioxidant activity of onion skin is closely correlated with the total content of phenolic compounds, mainly quercetin. (Franssinetti, Della-Croce, Caltavuturo, & Longo, 2012). Quercetin is reported to possess strong free radical scavenging activity based on its ability to act as hydrogen or electron donors and chelate transition metals (Belinha et al, 2007).…”

Section: Antioxidant Activity Of Onion Skin Extractmentioning

confidence: 99%

Onion skin extract as a protective agent against oxidative stress in Saccharomyces cerevisiae induced by cadmium

Piechowiak

Balawejder

2019

J Food Biochem

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Onion skin extract is a source of bioactive compounds demonstrating a high antioxidant activity. The purpose of this research was to investigate the effect of onion skin extract at the level of oxidative stress markers in Saccharomyces cerevisiae exposed to cadmium. The generation of reactive oxygen species (ROS), antioxidant enzymes activity, total content of glutathione, and the level of lipid peroxidation in yeast cells were determined. Research showed that onion skin extract protected the yeast cells from the occurrence of oxidative stress induced by cadmium. Cells treated with onion skin extract and cadmium were characterized by lower generation of ROS, antioxidant enzymes activity, lipid peroxidation, and higher level of glutathione content than cells treated with cadmium only. However, the protective effect was dependent on the onion skin extract concentration in yeast medium. Practical applications The presented studies are of comprehensive character regarding antioxidant properties of the onion skin extract, using Saccharomyces cerevisiae as a model organism. The research results give the opportunity to conduct further research on the use of onion skin extract in functional food or dietary supplements production, as a cellular protector against negative consequence of oxidative stress. It should also be mentioned that the major research material was onion skin which is a troublesome waste material for onion producers. Consequently, the study result will, to a certain extent provide an opportunity to increase interest in the problem of rational use of the waste material, according to a sustainable development idea.

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Section: Antioxidant Activity Of Onion Skin Extractmentioning

confidence: 99%

Onion skin extract as a protective agent against oxidative stress in Saccharomyces cerevisiae induced by cadmium

Piechowiak

Balawejder

2019

J Food Biochem

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“…Saccharomyces cerevisiae wild type strain BY4741 and its isogenic deletion strains sod1 Δ and tsa1 Δ were used in the present study to validate the antioxidant potential of ethanolic leaf extract of A. nilotica in in vivo condition. Yeast cells were grown up to the middle of the first exponential phase (OD 600 0.5) in liquid YPD (10 g L −1 yeast extract, 20 g L −1 peptone, 20 g L −1 glucose) medium in an orbital shaker at 50 × g and 30 °C …”

Section: Methodsmentioning

confidence: 99%

Determination of antioxidant potential ofAcacia niloticaleaf extract in oxidative stress response system ofSaccharomyces cerevisiae

et al. 2017

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“…The antioxidant activity of Lisosan G was previously evaluated through in vitro and in vivo experiments (Longo et al, 2007;Frassinetti et al, 2012;La Marca et al, 2013;Longo et al, 2014). Frassinetti et al (2012) demonstrated that Lisosan G removed the free radicals that originated from a normal aerobic metabolism and increased CAT, glutathione peroxidase (GPX) and superoxide dismutase (SOD).…”

Section: Discussionmentioning

confidence: 99%

The effects of fermented wheat powder (Lisosan G) on the blood lipids and oxidative status of healthy rabbits

Pozzo

Vizzarri

Ciardi

et al. 2015

Food and Chemical Toxicology

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Antimutagenic and antioxidant activity of Lisosan G in Saccharomyces cerevisiae

Cited by 30 publications

References 29 publications

Onion skin extract as a protective agent against oxidative stress in Saccharomyces cerevisiae induced by cadmium

Onion skin extract as a protective agent against oxidative stress in Saccharomyces cerevisiae induced by cadmium

Determination of antioxidant potential ofAcacia niloticaleaf extract in oxidative stress response system ofSaccharomyces cerevisiae

The effects of fermented wheat powder (Lisosan G) on the blood lipids and oxidative status of healthy rabbits

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