Antimycotic activity of Myrtus communis L. towards Candida spp. from clinical isolates

Cannas, Sara; Molicotti, Paola; Ruggeri, M.; Cubeddu, Marina; Sanguinetti, Maurizio; Zanetti, Stefania Anna Lucia

doi:10.3855/jidc.2799

Cited by 41 publications

(34 citation statements)

References 15 publications

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“…The essential oils and extracts are gaining remarkable interest for their potential multipurpose use as an antioxidant (Amira et al, 2012;Serce et al, 2010), antibacterial (Appendino et al, 2006), antifungal (Cannas et al, 2013), and antiseptic (Cakir, 2004) agents. The effects of the essential oil of M. communis on the growth and survival of H. pylori were assessed and the results showed that the essential oil of this plant represented clear activity against clinical isolates of H. pylori (Deriu et al, 2007).…”

Section: Myrtus Communismentioning

confidence: 99%

Medicinal plants in the treatment ofHelicobacter pyloriinfections

Safavi

Shams-Ardakani

Foroumadi

2014

Pharmaceutical Biology

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Context: Helicobacter pylori is a small, spiral, Gram-negative bacillus that plays a role in the pathogenesis of a number of diseases ranging from asymptomatic gastritis to gastric cancer. Schedule compliance, antibiotic drug resistance, and side-effects of triple or quadruple therapy have led to research for novel candidates from plants.Objective: The purpose of this paper is to review the most potent medicinal plants of recently published literature with anti-H. pylori activity. For centuries, herbals have been used by traditional healers around the world to treat various gastrointestinal tract disorders such as dyspepsia, gastritis, and peptic ulcer disease. The mechanism of action by which these botanicals exert their therapeutic properties has not been completely and clearly elucidated. Anti-H. pylori properties may be one of the possible mechanisms by which gastroprotective herbs treat gastrointestinal tract disorders. Materials and methods: Electronic databases such as PubMed, Google scholar, EBSCO, and local databases were explored for medicinal plants with anti-H. pylori properties between 1984 and 2013 using key words ''medicinal plants'' and ''Helicobacter pylori'' or ''anti-Helicobacter pylori''. Results: A total of 43 medicinal plant species belonging to 27 families including Amaryllidaceae,

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Section: Myrtus Communismentioning

confidence: 99%

Medicinal plants in the treatment ofHelicobacter pyloriinfections

Safavi

Shams-Ardakani

Foroumadi

2014

Pharmaceutical Biology

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“…More recently the pharmacological proprieties of its essential oil have been deeply explored. Antimicrobial properties (Deriu et al, 2007;Gündüz et al, 2009;Cannas et al, 2013), antihyperglycemic activities (Sepici et al, 2004;Onal et al, 2005), and antioxidant activity and fatty acid composition (Serce et al, 2010) have been also reported. A recent ethnobotanical study conducted by Leto et al (2013) showed effective medicinal use in both Italy (Sicily, Tuscany, and Sardinia) and Tunisia.…”

Section: Introductionmentioning

confidence: 99%

Morphological, chemical, and genetic diversity of wild myrtle(Myrtus communis L.) populations in Sicily

Melito¹,

Bella²,

Martinelli³

et al. 2016

Turk J Agric For

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Myrtus communis L. is a shrub widespread in the Mediterranean area. The interest in this species is growing, mainly due to its pharmacological and aromatic properties. The overexploitation of wild populations induced increasing degradation of plant cover with serious risk of loss of genetic diversity. This research explored the morphological, chemical, and genetic diversity of wild myrtle populations in Sicily, with the aim to provide a first characterization of a core collection of 36 accessions from 7 localities for future domestication programs. Amplified fragment length polymorphism fingerprinting generated 152 polymorphic fragments. STRUCTURE analysis identified three genetic clusters (A, B, and C) corresponding to specific geographical origin. Analysis of molecular variance estimated a quite high overall fixation index (F ST = 0.332). Misilmeri and Ispica were the more divergent populations (F ST = 0.502), while M. Pellegrino and Scopello revealed the lowest F ST (0.153). The relationships between genetic, morphological, and biometric data were investigated. Significant correlation between genetic clusters and bush shape/plant growth behavior was found (P < 0.005). Moreover, morphological traits such as leaf, fruit, and seed size were significantly correlated to Clusters B and C. Leaves' secondary metabolite profiles were evaluated based on antioxidant activity and total tannin and phenol concentrations. High antioxidant activity differences were recorded using DPPH (21.4-35.5 mmol Trolox/100 g DW) and ABTS (24.2-39.5 mmol Trolox/100 g DW) methods. A low variability was observed among populations regarding phenol (2466-3800 mg catechin equivalents/100 g DW) and total tannin contents (93.9-262.3 mg catechin equivalents/100 g DW). Results indicated that multiple approaches based on genetic, morphological, and chemical traits might allow the characterization of natural myrtle diversity.

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“…Despite the differences in the chemical composition of the EOs, they share some general properties, such as antiseptic, antibacterial, antifungal, and antioxidant activities [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Essential oils in ocular pathology: an experimental study

Cannas

Usai

Pinna

et al. 2015

J Infect Dev Ctries

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Introduction: The antimicrobial activity of essential oils (EOs) has been known for ages; in particular, the EOs of Melaleuca alternifolia, Thymus vulgaris, Mentha piperita, and Rosmarinus officinalis have been used for the treatment of fungal and bacterial infections. Methodology: This study focused on the in vitro cytotoxicity to normal human conjunctiva cells and antimicrobial activity of 20 EOs. Results: The oils tested showed no cytotoxic effect at very low concentrations. Rosmarinus officinalis, Melaleuca alternifolia, and Thymus vulgaris L. red thyme geraniol sel oils had good antimicrobial activity against Gram-positive and Gram-negative strains. Conclusions: The results of this study are of great interest and may have a major impact on public health, providing useful tips to optimize the therapeutic use of some natural drugs.

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Antimycotic activity of Myrtus communis L. towards Candida spp. from clinical isolates

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Cited by 41 publications

References 15 publications

Medicinal plants in the treatment ofHelicobacter pyloriinfections

Medicinal plants in the treatment ofHelicobacter pyloriinfections

Morphological, chemical, and genetic diversity of wild myrtle(Myrtus communis L.) populations in Sicily

Essential oils in ocular pathology: an experimental study

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