Antineoplastic Drugs: Occupational Exposure and Side Effects

Ivanova, Kristīne; Avota, Marija

doi:10.1515/prolas-2016-0049

Cited by 3 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies have also shown that these nurses are exposed to physical risks at work. Moreover, there are several reports of physical damages caused by exposure to chemotherapy medicines (Broto et al, 2017;Ivanova & Avota, 2016). By conducting interventions such as engineering control, supplying safety equipment, environment monitoring, supervising the use of antineoplastic medicines and providing educational courses, exposure to hazardous drugs in the workplace can be reduced (Crickman & Finnell, 2016).…”

Section: Discussionmentioning

confidence: 99%

Occupational stressors in oncology nurses: A qualitative descriptive study

Soheili

Taleghani

Jokar

et al. 2021

Journal of Clinical Nursing

View full text Add to dashboard Cite

Aim and objectives: The present study aims at exploring oncology nurses' perceptions regarding work-related stressors.Background: Oncology nurses work in an environment with a high degree of stress, which can negatively affect their health. There is limited research on work-related stressors from the oncology nurses' perspective.Design: Qualitative descriptive study.Methods: Fifty-two oncology nurses were selected purposefully from eight cancer treatment centres in different cities of Iran. Data were collected through semistructured interviews and analysed using conventional content analysis. The COREQ checklist was used to document the report of the study. Results:The extracted contents were classified into four main categories. The first category involved personal ability with two subcategories (person-job fit and psychological competencies). The second category included physical environment arrangements with two subcategories (physical working conditions and equipment and facilities). The third category involved psychosocial safety in the workplace with four subcategories (creating a safe work environment, overcoming the challenges of providing care to cancer patients, work/life balance and social recognition of the nursing status). The fourth category holds an organisational context with four subcategories (organisational support, interpersonal relations, justice at work and human resources). Conclusion:It is necessary to find measures attenuating work-related stresses in oncology nurses. These measures should be in line with developing personal abilities in nurses and creating a safe environment in terms of optimising physical, psychosocial and organisational conditions. It is also important to develop programmes protecting the oncology nurses' occupational health. Relevance to clinical practice:The results of this study can help improve nursing work conditions, attenuate work-related stresses in nurses and introduce efficient interventions reducing occupational stressors.

show abstract

Section: Discussionmentioning

confidence: 99%

Occupational stressors in oncology nurses: A qualitative descriptive study

Soheili

Taleghani

Jokar

et al. 2021

Journal of Clinical Nursing

View full text Add to dashboard Cite

show abstract

Cordia lutea L. Flowers: A Promising Medicinal Plant as Chemopreventive in Induced Prostate Carcinogenesis in Rats

Rojas-Armas

Arroyo-Acevedo

Ortiz-Sánchez

et al. 2020

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

The objective of this study was to evaluate the chemopreventive effect of the ethanolic extract of Cordia lutea flowers (EECL) on N-methyl-N-nitrosourea- (MNU), cyproterone-, and testosterone-induced prostate cancer in rats. 40 Holtzman male rats were used and assigned to 5 groups (n = 8). In Group I, rats received normal saline (10 mL/Kg); Group II: rats were induced for prostate cancer with cyproterone, testosterone, and NMU; Groups III, IV, and V: rats received EECL daily, at doses of 50, 250, and 500 mg/kg body weight, respectively. After the period of treatment, animals were sacrificed by an overdose of pentobarbital and blood samples were collected for determination of prostate-specific antigen (PSA). The prostate was dissected and weighed accurately. The ventral lobe of the prostate was processed for histopathology analysis. The somatic prostate index decreased with EECL at dependent dose, from 0.34 ± 0.04 to 0.23 ± 0.05 (P<0.05). The PSA levels also decreased significantly at doses of 250 and 500 mg/kg. Histopathological analysis showed a decrease in the number of prostatic layers with high-grade prostatic intraepithelial neoplasia (HG-PIN) and low-grade prostatic intraepithelial neoplasia (LG-PIN) at the dose of 500 mg/kg. The ethanolic extract of Cordia lutea flowers had a chemopreventive effect on induced prostate cancer in rats.

show abstract

Knowledge, Attitude, and Practice of Nurses About Handling AntiNeoplastic Drugs at Hiwa Hospital in Sulaimaniyah, Iraq

Hussain,

Abdulkareem

2023

JZS

View full text Add to dashboard Cite

Background: Anti-neoplastic drugs (ANDs) are a medical therapy utilized to fight cancer. Due to the possible health risks, safe handling and occupational exposure to anti-neoplastic agents have become significant concerns for oncology nursing staff. Objective: To assess the knowledge, attitude, and practice of nurses in handling ANDs at Hiwa Hematology/Oncology Hospital in Sulaimaniyah, Iraq. Materials and Methods: A quantitative-descriptive cross-sectional design was carried out on 91 nurses working in Hiwa Hematology/Oncology Hospital from March to June 2022. A questionnaire was designed and constructed by the researcher. Results: The findings of this study showed that the higher percentages level of nurses' knowledge, attitude, and practice was 39.6%, 49.5%, and 51.6%, respectively, which indicated that the majority of participants in that hospital had a fair level of knowledge, attitude, and practice. A significant assertion was found between nurses' level of knowledge, attitude, and practice toward handling ANDs with age, employment status, years of experience in handling ANDs, receiving formal training, number of working hours per week, and exposure to an ANDs side effect. In addition, a highly significant association between nurses' level of knowledge, attitude, and practice toward handling ANDs (p=0.000) were found. Conclusion: We concluded that most of the sample had fair knowledge, attitude, and practice about handling ANDs, with a highly significant association.

show abstract

Antineoplastic Drugs: Occupational Exposure and Side Effects

Cited by 3 publications

References 4 publications

Occupational stressors in oncology nurses: A qualitative descriptive study

Occupational stressors in oncology nurses: A qualitative descriptive study

Cordia lutea L. Flowers: A Promising Medicinal Plant as Chemopreventive in Induced Prostate Carcinogenesis in Rats

Knowledge, Attitude, and Practice of Nurses About Handling AntiNeoplastic Drugs at Hiwa Hospital in Sulaimaniyah, Iraq

Contact Info

Product

Resources

About