Antinociceptive and anti-inflammatory effects of olive oil (Olea europeaeL.) in mice

The Effects of Olive Leaf Extract Ointment on Pain Intensity and Early Maternal Complications in Primiparous Women

“…Tocopherols are also among the major components of herbal oils, including olive oil, which are active as vitamin E. Similar to nonsteroid anti-inflammatory drugs, tocopherol metabolites inhibit cyclooxygenase enzyme, reduce prostaglandins production, and decrease pain. Hence, tocopherols and some fatty acids such as oleic acid can be effective in analgesic effects of olive oil [26]. It should be noted that olive leaf extract rather than olive oil was used in the current study.…”

Comparison of 1% cyclosporine eye drops in olive oil and in linseed oil to treat experimentally-induced keratoconjunctivitis sicca in rabbits

“…These variations could be explained by the difference in composition for each oil. Olive oil contains a larger quantity of MUFA (70-80% oleic acid) and only a small amount of PUFA (5-10% of ω-3, ω-6, and ω-9) (10,11) . Linseed oil is comprised of 16% ω-6 and 57% ω-3, which are natural anti-inflammatory agents due to their ability to synthesize noninflammatory mediators (12,25) .…”

“…Olive oil, from the fruit of the olive tree Olea europaea, contains a significant concentration of monounsaturated fatty acids (MUFAs), of which 70-80% are oleic acid, in addition to 10-15% saturated fatty acids (palmitic acid) and 5-10% omega 3 (ω-3), 6 (ω-6), and 9 (ω-9) polyunsaturated fatty acids (PUFAs) (8) . Olive oil has been shown to possess antinociceptive, anti-inflammatory, antiarrhythmic, spasmolytic, immunostimulant, cardioprotective, hypotensive, hypoglycemic, and antimicrobial properties (9)(10)(11) . Linseed oil, from the flax plant Linum usitatissimum, is composed of 57% ω-3, 16% ω-6, 28% MUFA, and only 9% unsaturated fatty acids; the ω-3-to-ω-6 ratio of 1:3 is considered to be close to ideal (12) .…”

The effect of topical olive oil on prevention of bedsore in intensive care units patients

“…The protective effect of Olive oil can be most important in the first decades of life, which suggests that the dietetic benefit of Olive oil intake should be initiated before puberty, and maintained through life. [17][18][19][20] This oil is composed of 98% triglycerides, including predominantly monounsaturated oleic acid which has been proven to be essential for skin maintenance and this may accelerate the recovery and healing process of wound. The roll of oleic acid is a key feature within the reconstruction of cell membranes, providing higher smoothness to the dermis by restoring skin humidity levels, thus moisturizing the skin and providing it with elasticity.…”