Antinociceptive, Anti-Inflammatory, and Antipyretic Activity of Mangrove Plants: A Mini Review

Abstract

Mangrove plants are specialised plants that grow in the tidal coasts of tropic and subtropic regions of the world. Their unique ecology and traditional medicinal uses of mangrove plants have attracted the attention of researchers over the years, and as a result, reports on biological activity of mangrove plants have increased significantly in recent years. This review has been set out to compile and appraise the results on antinociceptive, anti-inflammatory, and antipyretic activity of mangrove plants. While the Web of Knowledge, Google Scholar, and PubMed were the starting points to gather information, other pieces of relevant published literature were also adequately explored for this purpose. A total of 29 reports on 17 plant species have been found to report such activities. While 19 reports were on the biological activity of the crude extracts, 10 reports identified the active compound(s) of various chemical classes of natural products including terpenes, steroids, and flavonoids. This review finds that antinociceptive, anti-inflammatory, and antipyretic activity appears to be widespread in mangrove plants.

The genusAvicennia, a pioneer group of dominant mangrove plant species with potential medicinal values: a review

“…From many of the ethnomedicinal uses of the genus, the widest applications have been in the treatment of rheumatism, pregnancy, ulcer and smallpox (Bandaranayake 2002). Different parts of the plant such as leaf, bark/stem, seeds, roots and fruits have been exploited over the years for the treatment of various diseases (Shilpi et al 2012;Simlai & Roy 2013). Plants like Avicennia alba Blume (a variant to A. marina), A. marina, A. nitida and A. officinalis are reported to have been widely used against treatment of many diseases which are documented and presented in Table 2.…”

Anti‐MRSA activity of oxysporone and xylitol from the endophytic fungus Pestalotia sp. growing on the Sundarbans mangrove plant Heritiera fomes

“…Because of the scant distribution of the mangrove forests, mangrove plant species are still almost unacquainted to a vast population. Ancient people used mangrove plant species scarcely, because they could hardly enter these areas (Shilpi et al, ). Heritiera fomes Buch.…”

COX-2 inhibitors from the leaves of Pellacalyx saccardianus Scortech (Rhizophoraceae)

“…For example, the crude extract from the bark of Rhizophora mangle was shown to have significant gastroprotective activity (Berenguer et al, 2006), and the ethanol extract of the leaves of Ceriops decandra was reported to have antinociceptive activity (Shilpi et al, 2012). The Rhizophoraceae species Rhizophora mucronata and Ceriops tagal are used in herbal medicine to control diabetes, and in vitro screening of the 80% aqueous ethanolic extracts from the bark of these species revealed high activity against a-glucosidase, with IC 50 values of 0.08 AE 1.82 and 0.85 AE 1.46 mg/mL, respectively (Lawag et al, 2012).…”