Antioxidant activity and phenolic composition in pomegranate (<scp><i>Punica granatum</i></scp> L.) genotypes from south Italy by UHPLC–Orbitrap‐MS approach

Stefano, Vita Di; Pitonzo, Rosa; Novara, Maria Eugenia; Bongiorno, David; Indelicato, Serena; Gentile, Carla; Avellone, Giuseppe; Bognanni, R.; Scandurra, S.; Melilli, M.G.

doi:10.1002/jsfa.9270

Cited by 59 publications

(57 citation statements)

References 38 publications

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“…Non‐flavonoid compounds are mainly phenolic acids, including hydroxycinnamic acid and hydroxybenzoic acid. The amounts of phenolic compounds can be affected by cultivar, geographical region, ripening stages and extraction process …”

Section: Introductionmentioning

confidence: 99%

“…In the study reported here, five sweet cherry cultivars, Caihong, Sunburst, Summit, 23–51 and Valeri, taking into account their peel and flesh, were tested for phenolic characteristics. Phenolic compounds, including free, soluble conjugated and insoluble bound fractions, were qualitatively and quantitatively examined using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC‐MS/MS) . As far as we know, this is the first study focusing on the determination of phenolics using UPLC‐MS/MS in peel and flesh of sweet cherries separately.…”

Section: Introductionmentioning

confidence: 99%

“…The amounts of phenolic compounds can be affected by cultivar, geographical region, ripening stages and extraction process. [6][7][8][9] Some studies have focused on the analysis of the difference in phenolic levels between cherry cultivars. 2,10 The most abundant phenolics in sweet cherry are anthocyanins, 11,12 of which cyanidin-3-O-rutinoside is the predominant one.…”

Section: Introductionmentioning

confidence: 99%

“…Phenolic compounds, including free, soluble conjugated and insoluble bound fractions, were qualitatively and quantitatively examined using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). 8,9,30,31 As far as we know, this is the first study focusing on the determination of phenolics using UPLC-MS/MS in peel and flesh of sweet cherries separately. The differences of phenolic composition among the cherry cultivars with different species and edible parts will provide comprehensive information on the important nutritional components, and cherries with high phenolic content may be useful for cherry breeding in future.…”

Section: Introductionmentioning

confidence: 99%

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Use of ultra‐performance liquid chromatography–tandem mass spectrometry on sweet cherries to determine phenolic compounds in peel and flesh

et al. 2019

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BACKGOUND Sweet cherries (Prunus avium L.) are rich in polyphenols and have high antioxidant potential. This study deals with the use of ultra‐performance liquid chromatography–tandem mass spectrometry on five cherry cultivars, namely Caihong, Sunburst, Summit, 23–51 and Valeri, to determine the free, conjugated and bound phenolics in peel and flesh. RESULTS Phenolics varied widely based on cherry cultivars and edible parts. Valeri showed the highest phenolics in peel, while the flesh of 23–51 contained a higher amount of phenolic substances compared with the other cherries, mainly due to high levels of cyanidin‐3‐O‐rutinoside, which was the most abundant phenolic in sweet cherry. Most of the phenolics, except for ferulic acid and vanillic acid, were present at a higher level in peel than in flesh. Principal component analysis indicated that compared with different edible parts, the phenolic compounds were more influenced by cultivar. CONCLUSIONS Cultivar had a much greater impact on the accumulation of phenolics than edible parts. The peel of Valeri contained the highest phenolics; for the flesh, 23–51 had the highest levels. The high variability in phenolic compounds in peel and flesh among cultivars may be useful for breeding and underlines the importance of germplasm conservation activities. © 2019 Society of Chemical Industry

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Use of ultra‐performance liquid chromatography–tandem mass spectrometry on sweet cherries to determine phenolic compounds in peel and flesh

et al. 2019

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“…Such compounds have antioxidant (Banihani, Shuaibu, Al-Husein, & Makahleh, 2019;Di Stefano et al, 2018), anti-carcinogenic (Sharma et al, 2017), anti-atherogenic (Rosenblat, Volkova, Borochov-Neori, Judeinstein, & Aviram, 2015), anti-inflammatory (Cho & Song, 2018), antihypertensive (Stowe, 2011), and antihyperglycemic effects (Banihani et al, 2014). Such compounds have antioxidant (Banihani, Shuaibu, Al-Husein, & Makahleh, 2019;Di Stefano et al, 2018), anti-carcinogenic (Sharma et al, 2017), anti-atherogenic (Rosenblat, Volkova, Borochov-Neori, Judeinstein, & Aviram, 2015), anti-inflammatory (Cho & Song, 2018), antihypertensive (Stowe, 2011), and antihyperglycemic effects (Banihani et al, 2014).…”

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confidence: 99%

Effect of fresh pomegranate juice on the level of melatonin, insulin, and fasting serum glucose in healthy individuals and people with impaired fasting glucose

Banihani

Fashtaky

Makahleh

et al. 2019

Food Science & Nutrition

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Pomegranate juice (PGJ) is rich in unique bioactive compounds that can be used in the management of various diseases/disorders such as cancer, heart disease, Alzheimer disease, hypertension, and diabetes. Here, we aimed to investigate the effects of fresh PGJ on levels of melatonin, insulin, and fasting blood glucose in people with impaired fasting glucose (IFG). The study was a randomized clinical trial in which 28 participants (10 males, 18 females) with IFG were recruited from Irbid Central Laboratory and the Diabetes Technology. Blood specimens from each participant were collected before (−5 min), and 1 and 3 hr after PGJ administration at 1.5 ml/kg of the body weight, and melatonin, insulin, and glucose were measured. People with IFG, but not healthy individuals, had significant antihyperglycemic response (p < .0001) to PGJ 3 hr after ingesting the juice. This response was not correlated with the age of participants (p = .4287).In addition, homeostatic model assessment of insulin resistance was significantly decreased (p < .0001) among people with IFG 3 hr after ingesting the juice. Moreover, 1 hr after PGJ administration, decreases in melatonin and increases in insulin were significantly observed among healthy (p = .0284, p = .0017) and IFG (p = .0056, p = .0007) individuals, respectively. In conclusion, fresh PGJ lowers melatonin, increases the level of insulin, and ameliorates insulin resistance in people with IFG.

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Anthocyanins from Pomegranate (Punica granatum L.) and Their Role in Antioxidant Capacities in Vitro

Zhao

Yuan

2021

Chemistry & Biodiversity

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As phytochemicals, anthocyanins are not only responsible for the diverse colors in nature, but are associated with broad‐spectrum health‐promoting effects for human beings. Pomegranate is abundant in anthocyanins which possess high antioxidant capacities. However, the pomegranate anthocyanins profile and their contributions to antioxidant capacities are not fully depicted. The purpose of this article is to review anthocyanins from pomegranate as important antioxidants. Total anthocyanin content (TAC) and six major components vary greatly with intrinsic and extrinsic factors. In pomegranate, anthocyanins mainly acted as primary antioxidants, while their action as secondary antioxidants were not conclusive. The antioxidant potentials of anthocyanins were significantly affected by factors especially chemical structure and detection assays in vitro. The current knowledge may provide insights into potential applications for pomegranate anthocyanins based on their antioxidant activities.

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Antioxidant activity and phenolic composition in pomegranate (Punica granatum L.) genotypes from south Italy by UHPLC–Orbitrap‐MS approach

Cited by 59 publications

References 38 publications

Use of ultra‐performance liquid chromatography–tandem mass spectrometry on sweet cherries to determine phenolic compounds in peel and flesh

Use of ultra‐performance liquid chromatography–tandem mass spectrometry on sweet cherries to determine phenolic compounds in peel and flesh

Effect of fresh pomegranate juice on the level of melatonin, insulin, and fasting serum glucose in healthy individuals and people with impaired fasting glucose

Anthocyanins from Pomegranate (Punica granatum L.) and Their Role in Antioxidant Capacities in Vitro

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