Antioxidant activity and phenolic compounds of fractions from Portulaca oleracea L.

Erkan, Naciye

doi:10.1016/j.foodchem.2012.01.091

Cited by 118 publications

(85 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the current study the chromatographic analysis of the aqueas extract revealed phenolic compound fractionated to catechein, chlorogenic, salcylic and pyrogalol while flavonoids were fractionated to rosmarinic, rutin, quercitrin; these results are in agreement to the results obtained by Naciye [36] and Abd El-Aziz et al [37]. …”

Section: Discussionsupporting

confidence: 92%

Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats

Ramadan

Schaalan

Tolba

2017

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundDiabetes is a major public health concern. In spite of continuous new drug development to treat diabetes, herbal remedies remain a potential adjunct therapy to maintain better glycemic control while also imparting few side-effects. Portulaca oleracea has been traditionally used to manage several diseases due to the anti-oxidant and anti-atherogenic effects it imparts. To better understand the mechanisms associated with potential protective effect of P. oleracea extract against diabetes, alloxan-induced diabetic rats were used in this study.MethodsForty Wistar rats (male, 7–8-wk-old, 140–160 g) were divided into four groups (n = 10/group): Group I (control), Group II (P. oleracea-treated; gavaged with P. oleracea extract daily [at 250 mg/kg] for 4 weeks), Group III (diabetic control; daily IP injection of alloxan [at 75 mg/kg] for 5 days) and Group IV (P. oleracea-pre-treated diabetic; gavaged with P. oleracea extract daily [at 250 mg/kg] for 4 weeks and then daily IP injection of alloxan [at 75 mg/kg] for 5 days). Body weight, food consumption, blood (serum) levels of glucose, C peptide, Hb A1C, insulin, tumor necrosis factor (TNF)-α and interleukin (IL)-6 were determined for all groups.ResultsThe results indicated that while Hb A1C, serum levels of glucose, TNF-α and IL-6 were all significantly decreased in the P. oleracea-pre-treated diabetic rats, these hosts also had significant increases in C peptide and insulin compared to levels in the counterpart diabetic rats. These results were confirmed by the histopathological assessments which showed marked improvement of the destructive effect on pancreatic islet cells induced by alloxan.ConclusionP. oleracea extract is a general tissue protective and regeneartive agent, as evidenced by increasing β-cell mass and therefore improved the glucose metabolism. Thus, stimulation of Portulaca oleracea signaling in β- cells may be a novel therapeutic strategy for diabetes prevention.

show abstract

Section: Discussionsupporting

confidence: 92%

Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats

Ramadan

Schaalan

Tolba

2017

BMC Complement Altern Med

View full text Add to dashboard Cite

show abstract

“…Herbal medicines have long been viewed as a source of curative remedy based on religious and cultural traditions (Ghazanfer, 1994;Pal and Shukla, 2003;Saetung et al, 2005). Portulaca oleracea (purslane), is well known for its preventive and pharmacological potential, such as anti-inflammatory (Chan et al, 2000), antioxidative (Dkhil et al, 2011;Erkan et al, 2012), anti-bacterial (Zhang et al, 2002) activities. Thus, in order to provide comparative data on in vitro anticancer activity of the extracts of Portulaca oleracea (PO) and Petroselinum sativum (PS) on human hepatocellular carcinoma cell lines (HepG2), the present study was designed.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxicity Assessments of Portulaca oleracea and Petroselinum sativum Seed Extracts on Human Hepatocellular Carcinoma Cells (HepG2)

Farshori

Al-Sheddi²,

Al-Oqail³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

“…The main active ingredients of P. oleracea are flavonoids (Yan et al, 2012). Previous pharmacological investigations have indicated that flavonoids from P. oleracea have anti-oxidant (Erkan, 2012), anti-inflammatory (Tadic et al, 2012), anti-bacterial (Cushnie and Lamb, 2005), wound healing (Anitha et al, 2011), and anti-tumour effects (Xu et al, 2011). Some of these activities have also been shown in different P. oleracea extracts (Chan et al, 2000;Rashed et al, 2003;Lim and Quah, 2007;Shen et al, 2013;Ullah et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Previous pharmacological investigations have indicated that flavonoids from P . oleracea have anti‐oxidant (Erkan, ), anti‐inflammatory (Tadic et al , ), anti‐bacterial (Cushnie and Lamb, ), wound healing (Anitha et al , ), and anti‐tumour effects (Xu et al , ). Some of these activities have also been shown in different P .…”

Section: Introductionmentioning

confidence: 99%

A Rapid Extraction and Analysis Method for the Simultaneous Determination of 26 Bioflavonoids in Portulaca Oleracea L.

Liang

Tian

et al. 2014

Phytochem. Anal.

View full text Add to dashboard Cite

show abstract

Antioxidant activity and phenolic compounds of fractions from Portulaca oleracea L.

Cited by 118 publications

References 35 publications

Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats

Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats

Cytotoxicity Assessments of Portulaca oleracea and Petroselinum sativum Seed Extracts on Human Hepatocellular Carcinoma Cells (HepG2)

A Rapid Extraction and Analysis Method for the Simultaneous Determination of 26 Bioflavonoids in Portulaca Oleracea L.

Contact Info

Product

Resources

About