Antioxidant Activity of Essential Oil and Extracts ofValeriana jatamansiRoots

Abstract

Valeriana jatamansi is an indigenous medicinal plant used in the treatment of a number of diseases. In the present study, chemical composition of the essential oil was determined by GC-MS. Seven major components were identified in Valeriana jatamansi essential oil, namely, β-vatirenene, β-patchoulene, dehydroaromadendrene, β-gurjunene, patchoulic alcohol, β-guaiene, and α-muurolene. Methanolic, aqueous, and chloroform extracts of Valeriana jatamansi roots were also prepared and analyzed for their polyphenols and flavonoid content. Antioxidant activity of essential oil and different extracts of Valeriana jatamansi roots was determined by DPPH radical scavenging and chelation power assay. A linear correlation has been obtained by comparing the antioxidant activity and polyphenols and flavonoid content of the extracts. Results indicated that antioxidant activity of methanolic extract could be attributed to the presence of rich amount of polyphenols and flavonoid. Essential oil of Valeriana jatamansi roots showed moderate antioxidant activity.

Essential oil composition and antioxidant activity in Valeriana jatamansi Jones: influence of seasons and growing sources

“…The values of IC 50 were in the order: gallic acid < querecetin < tannic acid < ascorbic acid < essential oil samples of the species. Similarly, Thusoo et al (33) found IC 50 value of V. jatamansi as 876 μg/mL by using DPPH assay collected from Jammu and Kashmir region of Himalaya. Antioxidant activity analyzed by FRAP assay from the plant material of V. jatamansi from Khasi Hills of eastern Himalaya (12) essential β-selinene and α-guaiene were recorded higher in winter followed by spring and summer season.…”

Valeriana jatamansi: An herbaceous plant with multiple medicinal uses

“…In another experiment, 27 compounds were identified in the roots oil of V. jatamansi including patchoulol ( 247 ), α‐bulnesene ( 236 ), isovaleric acid ( 218 ), α‐guaiene ( 237 ), and 3‐methylvaleric acid ( 233 ) as the major compounds using GC–MS (Thusoo et al, ). Raina and Negi () studied 21 compounds in the oil isolated from roots of V. jatamansi by GC and GC–MS.…”

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“…DPPH assay has been extensively used for screening plant extracts because of its sensitivity to detect active ingredients at low concentrations 25 . The proton radical scavenging action is one of the various mechanisms for measuring antioxidant activity.…”