Antioxidant Activity of Flavanols and Flavonoid Glycosides in Oolong Tea

Sang, Shengmin; Zhu, Nanqun; Lin‐Shiau, Shoei‐Yn; Lin, Jyh-Woei; Ho, Chi‐Tang

doi:10.1021/bk-2002-0803.ch021

Cited by 1 publication

(1 citation statement)

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“…Compound 9 was determined to be 2-feruloyl- O -α- d -glucopyranoyl-(1′→2)-3,6- O -feruloyl-β- d -fructofuranoside, by comparing these data with previous reports [ 47 , 48 , 49 ]. Finally, compound 10 was identified as isoscutellarein 8- O -rhamnoside, which was confirmed by comparing the reported values with those of a previous study [ 50 ]. Consequently, three chlorogenic acid derivatives (compounds 2 – 4 ), one simple phenol (compound 1 ), four flavonoids (compounds 5 – 7 / 10 ), one stilbene (compound 8 ), and one phenylpropanoid glycoside (compound 9 ) were obtained from the 50% ethanol extract of SCS.…”

Section: Resultssupporting

confidence: 83%

Chemical Constituents of Smilax china L. Stems and Their Inhibitory Activities against Glycation, Aldose Reductase, α-Glucosidase, and Lipase

2017

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The search for natural inhibitors with anti-diabetes properties has gained increasing attention. Among four selected Smilacaceae family plants, Smilax china L. stems (SCS) showed significant in vitro anti-glycation and rat lens aldose reductase inhibitory activities. Bioactivity-guided isolation was performed with SCS and four solvent fractions were obtained, which in turn yielded 10 compounds, including one phenolic acid, three chlorogenic acids, four flavonoids, one stilbene, and one phenylpropanoid glycoside; their structures were elucidated using nuclear magnetic resonance and mass spectrometry. All solvent fractions, isolated compounds, and stem extracts from plants sourced from six different provinces of South Korea were next tested for their inhibitory effects against advanced glycation end products, as well as aldose reductase. α-Glucosidase, and lipase assays were also performed on the fractions and compounds. Since compounds 3, 4, 6, and 8 appeared to be the superior inhibitors among the tested compounds, a comparative study was performed via high-performance liquid chromatography with photodiode array detection using a self-developed analysis method to confirm the relationship between the quantity and bioactivity of the compounds in each extract. The findings of this study demonstrate the potent therapeutic efficacy of SCS and its potential use as a cost-effective natural alternative medicine against type 2 diabetes and its complications.

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Section: Resultssupporting

confidence: 83%