Antioxidant activity of polyphenolic compounds obtained from Euphorbia antisyphilitica by-products

Bautista-Hernández, Israel; Aranda-Ledesma, Néstor E.; Rojas, Romeo; Tafolla-Arellano, Julio C.; Martínez-Ávila, Guillermo Cristian Guadalupe

doi:10.1016/j.heliyon.2021.e06734

Cited by 20 publications

(13 citation statements)

References 51 publications

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“…The presences of phenoloic, flavonoid and tannin compounds in the tested plants could be linked with the antioxidant properties of these extracts. This is consistent with the several recent studies, which suggested that the antioxidant properties could be referred to phenolic compounds present in plants [70]. Among the reported secondary metabolites in plants, phenolic components had been recognized as excellent substances for reducing the oxidative damage caused by the free radical in living cells [74].…”

Section: Discussionsupporting

confidence: 90%

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Phenols, antioxidant and anticancer properties of Tagetes minuta, Euphorbia granulata and Galinsoga parviflora: in vitro and in silico evaluation

Al-Robai

Ahmed

et al. 2022

J.Umm Al-Qura Univ. Appll. Sci.

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This work aimed at assessing the phenolic content, antioxidant and cytotoxicity capacities of methanol extracts obtained from Tagetes minuta, Euphorbia granulata and Galinsoga parviflora medicinal plants. Standard spectrophotometric and chromatographic methods were used for chemical analysis. Established antioxidant and cytotoxicity assays were adopted for biological activity assessment. In silico screening for the individual phenolic acids was performed using molecular docking techniques. E. granulata showed a significantly high level of polyphenols. Highest level of flavonoid and tannin contents were detected in Galinsoga parviflora. Ten phenolic acids were identified and quantified via GC–MS in all extracts, and p-Hydroxybenzoic was the most dominant acid (70 µg/g) in T. minuta while gallic was the predominant acid (73 µg/g) in E. granulata. Extracts showed higher reactive oxygen and nitrogen species scavenging activities and exhibited lower hydrogen peroxide inhibition values. The strongest cytotoxic activity was exhibited by T. minuta extract on A2780 cell line. The cytotoxic activity of G. parviflora extract was highly significant against all cancer cells. Extract of E. granulata showed best activity towards MCF7 and A2780 cell lines and was less active against HT29 cell line. In silico data revealed that caffeic acid had the lowest value of binding energy and high ligand efficiency ratios against the selected target receptors, comparable to the standards. Methanol extracts of the targeted plants showed promising antioxidant and anticancer activities which could be attributed to presence of different phenolic phytochemicals. Further work is required for determining the active compounds and their mode of action.

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Section: Discussionsupporting

confidence: 90%

“…In previous studies, antioxidant activity was revealed in extracts from some species belong to the genus Euphorbia such as E. hirta, E. retusa and E. gaditana [70]. Mostafa et al [71] had reported that at concentration of 150 mg/ml, the ethyl acetate fraction from G. parviflora demonstrated strong antioxidant activity.…”

Section: Discussionmentioning

confidence: 99%

Phenols, antioxidant and anticancer properties of Tagetes minuta, Euphorbia granulata and Galinsoga parviflora: in vitro and in silico evaluation

Al-Robai

Ahmed

et al. 2022

J.Umm Al-Qura Univ. Appll. Sci.

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“…On the contrary, after digestion, a significant decrease occurred, and no significant differences between the two series of samples (WG and MG) were observed. This result could be related to the overall antioxidant activity of a mixture of compound results from that of a single bioactive and its synergic effect [ 50 ]. Herbal infusions usually decrease their antioxidant activity after GID [ 31 , 44 , 47 , 51 ].…”

Section: Discussionmentioning

confidence: 99%

Wild and Micropropagated Artemisia eriantha Infusions: In Vitro Digestion Effects on Phenolic Pattern and Antioxidant Activity

Rocchi,

Pellegrini,

Pittia

et al. 2023

Plants

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This study investigated the in vitro simulated gastrointestinal digestion (GID) effects on wild and micropropagated Apennines Genepì infusions. Wild and micropropagated infusions were compared for their antioxidant activity, phenolic contents, and polyphenolic profiles before and after GID. Before digestion, the wild infusions had higher amounts of phenolic compounds and antioxidant activity than the micropropagated ones. Instead, after digestion, the differences in the total phenolic content (TPC) and antioxidant activity between wild and micropropagated infusions were less pronounced. The changes in the TPC and phenolic profiles revealed the presence of several chemical transformations and rearrangements that resulted in compounds with different reactivity and antioxidant potential. Without enzyme actions, the wild infusion digest undergoes higher modifications than those obtained from the micropropagated ones. The current study offers the first concrete proof of the impact of GID on the polyphenolic chemicals present in infusions of wild and micropropagated Apennines Genepì and their antioxidant properties. Our findings are essential for future in-depth analyses of Apennine Genepì infusions and their potential impacts on human health.

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“…Oil samples exposed at 160 °C during 120 h were analysed by Fourier transform infrared spectroscopy according to Bautista‐Hernández et al . (2021). Spectral data and functional groups detected were analysed using MicroLab Expert program, and the plot was constructed using Statistica 10 software (StatSoft, Tulsa, OK, USA).…”

Section: Methodsmentioning

confidence: 99%

“…In order to acquire information about the changes that could occur at the molecular level after the heating process of canola oil, without and with pomegranate peel polyphenols, infrared spectra were obtained. Oil samples exposed at 160 °C during 120 h were analysed by Fourier transform infrared spectroscopy according to Bautista-Hernández et al (2021). Spectral data and functional groups detected were analysed using MicroLab Expert program, and the plot was constructed using Statistica 10 software (StatSoft, Tulsa, OK, USA).…”

Section: Ft-ir Spectra Analysismentioning

confidence: 99%

Effect of spray‐dried pomegranate peel polyphenols on the inhibition of lipid oxidation

Michel,

Martínez‐Torres,

Ávila‐Hernández

et al. 2023

Int J of Food Sci Tech

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SummaryPomegranate‐peel polyphenols, specifically the punicalagin, have gained importance due to their potential antioxidant capacity, and because of this have been proposed different methodologies to encapsulate and protect the polyphenols for proposing their uses. The objective of the present work was to optimize the spray‐drying of pomegranate‐peel polyphenols and additionally to evaluate their antioxidant activity based on lipid oxidation inhibition. The spray‐drying process was optimized via Taguchi L9 orthogonal array considering the feed flow (3.0, 4.5, and 6.0 mL/min), temperature (125, 150, and 200 °C), and airflow (30, 35, and 40 m3/h). The lipid oxidation inhibition was the response variable. The optimal spray‐drying conditions were experimentally validated, and the changes in polyphenols were analysed by HPLC‐ESI‐MS. The spray‐drying conditions optimized at which the polyphenols better preserved their antioxidant capacity (i.e., 87.40 % of inhibition) were feed flow, 4.5 mL/min; temperature, 125 °C; and airflow, 35 m3/h. However, temperature control was the most critical factor for obtaining good quality spray‐dried polyphenols (37.65 % of influence). This permitted us to propose that spray‐dried pomegranate‐peel polyphenols could be used as antioxidants in edible oils.

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Antioxidant activity of polyphenolic compounds obtained from Euphorbia antisyphilitica by-products

Cited by 20 publications

References 51 publications

Phenols, antioxidant and anticancer properties of Tagetes minuta, Euphorbia granulata and Galinsoga parviflora: in vitro and in silico evaluation

Phenols, antioxidant and anticancer properties of Tagetes minuta, Euphorbia granulata and Galinsoga parviflora: in vitro and in silico evaluation

Wild and Micropropagated Artemisia eriantha Infusions: In Vitro Digestion Effects on Phenolic Pattern and Antioxidant Activity

Effect of spray‐dried pomegranate peel polyphenols on the inhibition of lipid oxidation

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