2023
DOI: 10.3390/ph16081184
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Antioxidant Activity of Quercetin-Containing Liposomes-in-Gel and Its Effect on Prevention and Treatment of Cutaneous Eczema

Chang Liu,
Xiaoman Cheng,
Yifang Wu
et al.

Abstract: Cutaneous eczema is a kind of skin disease is characterized by inflammation. The main manifestations are various types of dermatitis, eczema, and urticaria. There are usually complications such as erythema, blisters, and epidermal peeling. The quercetin might have a therapeutic effect on cutaneous eczema due to its favorable antioxidant activity and anti-inflammatory effects. Currently, there are few studies on transdermal administration of antioxidant drugs for the treatment of cutaneous eczema. The aim of th… Show more

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Cited by 4 publications
(1 citation statement)
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“…Table 1 delineates various prevalent drug nanocarriers, encompassing polymeric NPs, lipid NPs (such as liposomes, ethosomes, SLNs, and nanostructured lipid carriers), nanoemulsions, dendrimers, micelles, and inorganic NPs tailored for transdermal delivery. [18][19][20] Acne, psoriasis, ichthyosis [21][22][23] Anti-inflammatory [24,25] Nanostructured lipid carriers Yes No 50-500 Anti-inflammatory (Immuno-suppressive) [26] Local analgesic, anti-inflammatory [27,28] Antimicrobial [29] Anticancer [30] Nanoemulsions Yes No 10-1000 Cosmetic use: antioxidant, sunscreens, lipid carriers [31][32][33] Nonsteroidal anti-inflammatory drug carriers [34,35] Anticancer [36,37] Antimicrobial [38] Liposomes No Yes 100-200 Antimicrobial treatment [39,40] Eczema, psoriasis [41,42] Anti-inflammatory [43,44] Skin cancer [45,46] Local anesthesia [47,48] Ethosomes No Yes 100-200 Skin pathology [43,49] Skin cancer [50,51] Skin infections [52,53] Anti-inflammatory and analgesic [54,55] Micelles In the category of NPs, polymeric nanocapsules and nanospheres represent promising tools to increase the cutaneous permeation of pharmaceuticals and bioactive agents. Nanocapsules, characteri...…”
Section: Nanocarriers For Skin Applicationsmentioning
confidence: 99%
“…Table 1 delineates various prevalent drug nanocarriers, encompassing polymeric NPs, lipid NPs (such as liposomes, ethosomes, SLNs, and nanostructured lipid carriers), nanoemulsions, dendrimers, micelles, and inorganic NPs tailored for transdermal delivery. [18][19][20] Acne, psoriasis, ichthyosis [21][22][23] Anti-inflammatory [24,25] Nanostructured lipid carriers Yes No 50-500 Anti-inflammatory (Immuno-suppressive) [26] Local analgesic, anti-inflammatory [27,28] Antimicrobial [29] Anticancer [30] Nanoemulsions Yes No 10-1000 Cosmetic use: antioxidant, sunscreens, lipid carriers [31][32][33] Nonsteroidal anti-inflammatory drug carriers [34,35] Anticancer [36,37] Antimicrobial [38] Liposomes No Yes 100-200 Antimicrobial treatment [39,40] Eczema, psoriasis [41,42] Anti-inflammatory [43,44] Skin cancer [45,46] Local anesthesia [47,48] Ethosomes No Yes 100-200 Skin pathology [43,49] Skin cancer [50,51] Skin infections [52,53] Anti-inflammatory and analgesic [54,55] Micelles In the category of NPs, polymeric nanocapsules and nanospheres represent promising tools to increase the cutaneous permeation of pharmaceuticals and bioactive agents. Nanocapsules, characteri...…”
Section: Nanocarriers For Skin Applicationsmentioning
confidence: 99%