Antioxidant activity of the essential oils of five species of the family Lamiaceae

Stanisavljević, Dragana; Stojičević, Saša S.; Karabegović, Ivana; Veličković, Dragan T.; Djordjević, S.; Lazić, Miodrag L.

doi:10.1055/s-0031-1282365

Cited by 3 publications

(1 citation statement)

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“…The extract of Mentha species has been reported to have fungicidal, antiinflammatory, antimicrobial and antioxidant activities (Mimica-Dukic et al, 2003;Gulluce et al, 2007;Mkaddem et al, 2009). Stanisavljevic et al (2012) showed that the highest content of phenolic compounds in Mentha longifolia L. was found in the extract obtained from naturally dried plant materials. The dominant phenolic component in this extract was kaempferol 3-O-glucoside and the highest value of antioxidant activity was found in the extract obtained from the naturally dried herbs.…”

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confidence: 99%

Neuroprotective effect of pretreatment with Mentha longifolia L. extract on brain ischemia in the rat stroke model

Fathi

Oryan

Rafieian-Kopaei

et al. 2015

Arch biol sci (Beogr)

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Recent studies have suggested that Mentha longifolia L. extracts (ME) have anti-inflammatory and antioxidant activities. In this paper, we attempted to determine the effect of ME in a rat stroke model. Five groups of experimental animals were used (n=14); the first and second groups (control and sham, respectively) received intraperitoneal injections of daily-distilled water; the other three groups received 50, 100, and 200 mg/kg/day of ME for 21 days. Two hours after the last dose, each group was subdivided into a middle cerebral artery occlusion (MCAO) group operated for neuropathological assessment (neurologic deficit scores, infarct volume, brain edema, and blood-brain barrier (BBB) permeability), and an intact subgroup for the assessment of brain and serum antioxidant capacity and lipid peroxidation, respectively. Pretreatment with ME resulted in a significant reduction in total infarct volume, brain water content and Evans Blue extravasation in the ischemic hemisphere compared with the control. ME in doses of 100 and 200 mg/kg/day increased brain antioxidant capability in comparison with the control. The antioxidant capacity of the serum in the 100 mg/kg/day group was significantly higher than that of the control group. The level of malondialdehyde (MDA) in the brain was significantly elevated in the control group in comparison with other pretreated groups. Moreover, ME in doses of 100 and 200 mg/kg/day reduced the MDA level in the serum. This study showed that intraperitoneal injection of ME reduced infarct volume, brain edema, blood-brain barrier permeability, as well as lipid peroxidation, and improved antioxidant power.

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Section: Introductionmentioning

confidence: 99%

Neuroprotective effect of pretreatment with Mentha longifolia L. extract on brain ischemia in the rat stroke model

Fathi

Oryan

Rafieian-Kopaei

et al. 2015

Arch biol sci (Beogr)

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Chemical composition, antimicrobial, antioxidant and antitumor activity of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus vulgaris L. essential oils

Nikolić

Glamočlija

Ferreira³

et al. 2014

Industrial Crops and Products

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Aromatic plant species of genus Thymus are important medicinal plants, highly recommended due to a range of therapeutic properties of their essential oil (thyme oil): antirheumatic, antiseptic, antispasmodic, antimicrobial, cardiac, carminative, diuretic and expectorant. Oil is also beneficial in boosting the immune system, and helps to fight colds, flu, infectious diseases and chills. It is proved to be a urinary antiseptic, being very helpful for cystitis and urethritis. Scientific validation of traditional uses, and phytochemical and bioactivity evaluation of essential oils from Thymus serpyllum, Thymus algeriensis and Thymus vulgaris was performed. GC/MS analysis revealed thymol as major component of T. algeriensis, T. vulgaris and T.serpyllum, with a contribution of 56.02%, 48.92% and 38.50%, respectively. The three essential oils (EOs) exhibited a significant antimicrobial activity against all the tested strains, T. serpyllum oil being the most potent (MIC 2.5-5 µg/mL, MBC 5-10 µg/mL; MIC 1-2 µg/mL, MFC 2-4 µg/mL). In addition, T. serpyllum oil revealed the highest antioxidant activity in all the assays and was also the most effective one against all the tested cell lines, presenting GI 50 values of 7.02-52.69 µg/mL. Moreover, the EOs did not show any toxicity, at the tested concentrations (<400 µg/mL), for porcine liver primary cell culture. In addition to their traditional use in food and cosmetics, the great potential of the tested Thymus essential oils for application in oral disease and anticancer treatments, encourage further investigation.

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The impact of foliar fertilizers on growth and biochemical responses of Thymus vulgaris to salinity stress

Zrig

Ferreira

Hamouda³

et al. 2019

Arid Land Research and Management

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Antioxidant activity of the essential oils of five species of the family Lamiaceae

Cited by 3 publications

References 0 publications

Neuroprotective effect of pretreatment with Mentha longifolia L. extract on brain ischemia in the rat stroke model

Neuroprotective effect of pretreatment with Mentha longifolia L. extract on brain ischemia in the rat stroke model

Chemical composition, antimicrobial, antioxidant and antitumor activity of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus vulgaris L. essential oils

The impact of foliar fertilizers on growth and biochemical responses of Thymus vulgaris to salinity stress

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