Antioxidant activity, xanthine oxidase inhibitory activity, and compounds determination of Cipadessa baccifera leaf extract

Lubis, Syarifah Ramadhani; Subandi, Subandi; Muntholib, Muntholib; Abbas, Jamilah; Mozef, Tjandrawati

doi:10.1063/5.0053207

Cited by 2 publications

(1 citation statement)

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“…They also found 39.84% xanthine oxidase inhibitory activity, which came from many flavonoid compounds in the extract. C. baccifera extracted in ethanol and methanol showed the presence of alkaloids, flavonoids, saponins, terpenoids, tannins, and phenolic compounds (Lubis et al, 2021;Murkute & Shinde 2018). Methanol extract of stem and stem bark of C. baccifera also showed the content of secondary metabolites of tannins, phenols, and flavonoids (Patel et al, 2020).…”

Section: In Vitro Antioxidant Activitymentioning

confidence: 99%

In vitro Antimicrobial and Antioxidant Activity of Meliaceae Plants Collection of Eka Karya Bali Botanic Garden

Li’aini

Wibawa²,

Rahayu³

2022

molekul

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Meliaceae are popularly used to produce terpenoid and limonoid compounds. These compounds have the potential as antioxidants, antimicrobials, insecticides, antipyretics, and anthelmintics. This research aims to determine the antioxidant and antimicrobial activity of Meliaceae leaves extract of Eka Karya Bali Botanic Garden plants collection. The dried leaves of 15 species of Meliaceae were extracted by methanol. In vitro antimicrobial tests were carried out on agar media inoculated by selected microbe. On the other hand, the antioxidant activity was assayed by 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging. As a result, Aphanamixis polystachya against Aspergillus niger (35.21 mm) and Cladosporium sp. (46.21), Toona hexandra against Fusarium solani (37.31 mm), Dysoxylum cauliflorum against Candida albicans (38.19 mm), Chisocheton pentandrus against Salmonella typhimurium (39.53 mm), Sandoricum koetjape against Staphylococcus aureus (50.07 mm), and Toona hexandra against Streptococcus nutans (42.25 mm) exhibited the strongest inhibitory effect. Furthermore, the antioxidant screening showed that Cipadessa baccifera, C. pentandrus, and Sandoricum koetjape exhibited strong antioxidant activity, while T. ciliata showed a very strong antioxidant activity with IC50 33.64 μg/mL. This study reveals an initial screening of the potential of various types of Meliaceae as a source of antioxidants and antibacterials. Furthermore, this information can be used as a new alternative for pharmaceutical companies and the industrial sector in the development of new products.

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Section: In Vitro Antioxidant Activitymentioning

confidence: 99%