Antioxidant, alpha glucosidase and antibacterial evaluation of Syzygium mytifolium (Roxb.) Walp.

Abstract

Medicinal plants have been the major source of combating and treating infectious diseases and health disorders throughout the ages. To explore new sources of inexpensive and safe antioxidants and antibiotics. The antioxidant and antibacterial potential of different extracts Syzygium mytifolium (Roxb.) Walp. were evaluated through 1,1-Diphenyl-2-Picryl Hydrazyl (DPPH), ferric reducing antioxidant power (FRAP), ?-glucosidase inhibition, disk diffusion and agar well methods. The leaves, bark, root and whole plant of Syzygium mytifolium were extracted with various solvents viz ethanol, methanol and aqueous to give crude extracts, respectively. Among all, the ethanolic extract showed high antioxidant activity in terms of radical scavenging activity, reducing power and alpha-glucosidase inhibition at 1.84 µg/ml, 40.2 mmol/gm and 14.34 µg/ml, respectively. All the tested parts of the plant exhibited moderate to higher range of antibacterial activity against bacterial pathogens with the inhibition zones ranged between 2-27.8 mm. Syzygium mytifolium will serve as a very good source for the development of antioxidant supplements and antibiotics for addressing infectious pathogens and improvement of health status.

Review of Ethnopharmacology, Morpho-Anatomy, Biological Evaluation and Chemical Composition of Syzygium polyanthum (Wight) Walp.

“…Generally, the leaves of the Myrtaceae are in the opposite direction, internal phloem, evergreen and woody and abundance of oil glands in most of the members (38). The members are bisexual with polystemonous, fully inferior or partial inferior ovaries mostly with nectariferous hypanthium and actinomorphic flower (36).…”

“…History has shown that these species originated from South Asia countries like Nepal, Sri Lanka, Pakistan and India (38,43). Though they are distributed all over the world, they are mostly found in tropical and subtropical regions (43).…”

“…Members of this genus are reported to be rich in medicinally valuable volatile oils (46). Because of the extensive therapeutic potential, it has been widely disseminated (38).…”

“…Indian Baywatch, Bay leaf and Japanese Baywatch are some of the common names for this species. The plant can be found in forests, streams, humid rainforests or waterlogged environments and hilly areas (38).…”

“…Secondary metabolites come in a variety of shapes and functions, depending on the plant and its sections (38). Many nutritional supplements, nutraceuticals and functional food additives contain antioxidants, which help to preserve food by blocking oxidation processes and contribute to health promotion (53).…”