Antioxidant and acetylcholinesterase inhibition capacity of hyrosols from lamiaceae plants for biopesticide use: role of phenolics

Gaspar‐Pintiliescu, Alexandra; Mihai, Elena; Ciucan, Teodora; Popescu, Adriana Florina; Luntraru, Cristina; Tomescu, Justinian; Crăciunescu, Oana

doi:10.1080/10942912.2022.2071289

Cited by 15 publications

(10 citation statements)

References 53 publications

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“…Quercetin, as a flavonoid, has also been reported to have free radical scavenging properties ( 28 ). Polyphenolic compounds extracted from three Romanian Lamiaceae plants, sage ( Salvia officinalis ), rosemary ( Rosmarinus officinalis ) and lavender ( Lavandula angustifolia ) showed antioxidant activity ( 29 ). Further, in our study, all concentrations of TFH inhibited acetylcholinesterase and monoamine oxidase A in vitro .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)

Wang

Zhu

et al. 2022

Front. Nutr.

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The aim of this study was to investigate the antioxidative and neuroprotective activities of total flavonoids from sea buckthorn (Hippophae rhamnoides L.) (TFH). Results indicated that TFH possessed DPPH radicals, hydroxyl radicals and superoxide anions scavenging activities. The neuroprotective potential was assessed with acetylcholinesterase (AChE) and monoamine oxidase A (MAO-A). The inhibition rates of AChE and MAO-A by 50 μg/ml TFH were 75.85 and 51.22%, respectively. The in vivo antioxidative and neuroprotective potential of TFH were explored in Caenorhabditis elegans. In the longevity assay, TFH (50 μg/ml) significantly increased the lifespan of wild-type C. elegans (29.40%). In the hydrogen peroxide-induced oxidative stress challenge, the antioxidant capacity of TFH-treated wild-type C. elegans was significantly enhanced. The C. elegans mutant strain CL4176 was used to study the neuroprotective effect of TFH in vivo. Results showed that TFH significantly delayed paralysis in C. elegans CL4176. Our study suggested total flavonoids from sea buckthorn (Hippophae rhamnoides L.) had the potential as an antioxidative and neuroprotective agent to extend aging and treat neurodegenerative diseases.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)

Wang

Zhu

et al. 2022

Front. Nutr.

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“…In rosemary extract, the camphor, 1,8‐eucalyptol, linalool, and linalyl acetate in essential oils were generally believed to be critical antioxidant active ingredients, whereas the phenolic acids, flavonoids, and diterpenes (carnosic acid and carnosol) were considered as the main antioxidant active compositions in the non‐volatile rosemary extracts (Gaspar‐Pintiliescu et al., 2022; Lamponi et al., 2021). They act synergistically to catalyze reactive oxygen species (ROS) into stable products and then defend against oxidative stress at the cellular and molecular levels (Figure S2).…”

Section: Biological Activities Of Rosemary Extractmentioning

confidence: 99%

“…DPPH method showed that rosemary essential oil had an antioxidant effect with an IC 50 value of 460.37 ± 1.33 µg/mL (El Kharraf et al., 2021). Moreover, the higher content of the total phenol of rosemary hydrosol would provide much more significant antioxidant activity toward DPPH (Gaspar‐Pintiliescu et al., 2022).…”

Section: Biological Activities Of Rosemary Extractmentioning

confidence: 99%

Section: Nutritional and Chemical Compositionmentioning

confidence: 99%

“…In addition, its extract can inhibit the development of a variety of plant pathogens and act as a natural preservative to keep fruits and vegetables fresh during storage, due to its potent antibacterial and antioxidant activities. A huge number of excellent efforts have evidenced that the potent antioxidant properties of rosemary are mainly derived from its polyphenolic compounds, including flavonoids, non-flavonoids, and phenolic acids, especially the high-content carnosic acid (Gaspar-Pintiliescu et al, 2022;Kamli et al, 2022). The phenolic compounds of rosemary extract are mainly composed of flavonoids (such as luteolin, genkwanin, hesperidin, 7-O-methylrosmanol, isorhamnetin, and diosmin), phenolic acids (including rosmarinic acid, chlorogenic acid, caffeic acid, and ferulic acid), diterpene phenols (mainly carnosic acid, carnosol, and epirosmanol), and other components (Barbieri et al, 2020) (Figure 5).…”

Section: Polyphenol Profilesmentioning

confidence: 99%

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Rosemary: Unrevealing an old aromatic crop as a new source of promising functional food additive—A review

Qiu,

Wang,

Duan

et al. 2024

Comp Rev Food Sci Food Safe

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Rosemary (Rosmarinus officinalis L.) is one of the most famous spice plants belonging to the Lamiaceae family as a remarkably beautiful horticultural plant and economically agricultural crop. The essential oil of rosemary has been enthusiastically welcome in the whole world for hundreds of years. Now, it is wildly prevailing as a promising functional food additive for human health. More importantly, due to its significant aroma, food, and nutritional value, rosemary also plays an essential role in the food/feed additive and food packaging industries. Modern industrial development and fundamental scientific research have extensively revealed its unique phytochemical constituents with biologically meaningful activities, which closely related to diverse human health functions. In this review, we provide a comprehensively systematic perspective on rosemary by summarizing the structures of various pharmacological and nutritional components, biologically functional activities and their molecular regulatory networks required in food developments, and the recent advances in their applications in the food industry. Finally, the temporary limitations and future research trends regarding the development of rosemary components are also discussed and prospected. Hence, the review covering the fundamental research advances and developing prospects of rosemary is a desirable demand to facilitate their better understanding, and it will also serve as a reference to provide many insights for the future promotion of the research and development of functional foods related to rosemary.

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Alternative Strategies for Reducing Neonicotinoids Use

Chuskit,

Rana,

Gupta

et al. 2024

Sustainable Landscape Planning and Natural Resources Management

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Antioxidant and acetylcholinesterase inhibition capacity of hyrosols from lamiaceae plants for biopesticide use: role of phenolics

Cited by 15 publications

References 53 publications

Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)

Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)

Rosemary: Unrevealing an old aromatic crop as a new source of promising functional food additive—A review

Alternative Strategies for Reducing Neonicotinoids Use

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