Antioxidant and anti-apoptotic potential of whole-pomegranate extract promoted growth performance, physiological homeostasis, and meat quality of V-line rabbits under hot summer conditions

Imbabi, Tharwat A.; Ahmed-Farid, Omar A.; Selim, Dina A.; Sabeq, Islam

doi:10.1016/j.anifeedsci.2021.114911

Cited by 12 publications

(8 citation statements)

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“…It was reported earlier that after 5 days of storage at 3 °C, most of the rabbit carcasses had APC of about 7 log CFU/g and reached 8 logs CFU/g after 6 to 8 days [ 59 ]. In addition to strong antioxidant criteria due to the high content of polyphenols and flavonoids [ 43 , 60 ], this finding suggests that feeding fennel oil can potentially substitute antibiotics to improve the shelf-life of rabbit meat. These properties have also been widely reported for many other essential oils and their constituents [ 61 ].…”

Section: Discussionmentioning

confidence: 99%

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Impact of Fennel Essential Oil as an Antibiotic Alternative in Rabbit Diet on Antioxidant Enzymes Levels, Growth Performance, and Meat Quality

et al. 2021

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In the current study, fennel essential oil was used as an antibiotic alternative compared to gentamycin for enhancing the expression of apoptosis genes and antioxidant enzymes in weaned rabbits as well as meat quality and growth performance. The gene expression of the cell lymphoma 2 (BAX and BCL2), caspase3 (CASP3), and glutathione peroxidase (GPX1) were estimated in the liver tissue using qRT-PCR. A total of 45 Moshtohor weaned male rabbits aged four weeks were randomly allocated to control, T1, and T2 treatment groups; each consisted of 15 weaned male rabbits with five replicates. Rabbits in the T1 and T2 groups were orally supplied with 1 mL fennel oil and 1 mL gentamycin, respectively. Weaned rabbits under different treatments showed increased body weight (BW) at 8 and 12 weeks of age and average daily gain (ADG) at 4–8 and 4–12 weeks of age compared to the control group. Compared to the controls, the weaned rabbits supplemented with fennel oil and gentamycin had lower total cholesterol, triglyceride, and MDA. In addition, villus length, mRNA of BAX, BCL2, Casp3, and GPX were increased in the different treatments compared to the control. Furthermore, the meat of these rabbits was less tender, had a lower aerobic plate count (APC), pH, and was brighter and redder in color than the control. Under the conditions of the present study, the supplementation of weaned Moshtohor rabbits with fennel oil as a natural alternative for gentamycin enhanced feed conversion and daily gain through enhancing villus length and mucus thickness. Additionally, fennel essential oil reduces oxidative stress by increasing the antioxidant enzymes.

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Section: Discussionmentioning

confidence: 99%

“…Table 1. Primers used for quantitative real-time PCR analysis of gene expression according to Imbabi et al [43].…”

Section: Rna Isolation and Cdna Synthesismentioning

confidence: 99%

Impact of Fennel Essential Oil as an Antibiotic Alternative in Rabbit Diet on Antioxidant Enzymes Levels, Growth Performance, and Meat Quality

et al. 2021

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“…Due to lipid peroxidation brought on by DNA, protein, and cell phospholipid membrane damage, heat stress may increase the formation of reactive oxygen species (ROS) [4][5][6][7]. Rabbits are becoming more and more important in the global meat industry, but hot weather conditions have an impact on an animal's productive physiology and the quality of its meat, and animal mortality rises [8][9][10][11]. Since growing rabbits are particularly sensitive to high temperatures and suffer from heat anxiety during the summer, intensive rabbit production is impacted by environmental and nutritional factors [12,13].…”

Section: Introductionmentioning

confidence: 99%

Use of zinc oxide nanoparticles in the growing rabbit diets to mitigate hot environmental conditions for sustainable production and improved meat quality

et al. 2022

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Background This study evaluated the modulatory effects of zinc oxide nanoparticles (ZnO-NPs) supplementations on the productive performance, blood biochemistry, carcass criteria, and meat quality of White New Zealand rabbits reared under hot conditions. A total of 125 White New Zealand male rabbits (body weight, “650 ± 11”, 30 days old) were assigned to five treatment diets: basal diets supplemented with ZnO-NPs at 0, 20, 40, 60, or 80 mg/kg for 60 days. Each treatment was replicated 25 times with one rabbit each. Results The body weight (BW), BW gain, and feed intake linearly increased with zinc oxide nanoparticle supplements. Supplementation of ZnO-NPs at 20, 40, 60, and 80 mg/kg significantly improved (linear, P < 0.05) the feed conversion ratio compared to the control group. Moreover, supplementation of ZnO-NPs at these inclusions 20, 40, 60, and 80 mg/kg significantly (P < 0.05) decreased the serum cholesterol, alanine aminotransferase, and aspartate aminotransferase, creatinine, and urea compared to control group. The lipid oxidation was lower, and the water holding capacity of rabbit meat was improved (P < 0.001) in rabbits fed on 20, 40, 60, and 80 mg/kg ZnO-NPs supplemented diets compared to control. Conclusion The results suggested that dietary supplementation of ZnO-NPs (20–80 mg/kg) can mitigate the negative impacts of heat stress on rabbit performance and health. Its supplementation improved growth performance and meat physicochemical properties, and blood biochemistry parameters of White New Zealand rabbits.

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“…Fed a base diet with varying doses (ranging from 1,000 to 1,500 mg/kg) of whole-pomegranate extract for 60 days in the summer to the rabbits. LPO, AST, ALT, TC, TG, and WBC, which were negatively impacted by summer heat stress in the control rabbits, were dramatically reduced by the extract [ 46 ]. The presence of many phenolic components (ellagic acid, punicalin, and punicalagin) rather than a single pure polyphenol accounts for the pomegranate’s superior antioxidant action [ 47 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Feeding Pomegranate (Punica granatum) Peel and Garlic (Allium sativum) on Antioxidant Status and Reproductive Efficiency of Female Rabbits

Hagag

Younis

Al-Eisa

et al. 2023

Veterinary Sciences

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Egypt’s animal protein shortfall cannot be overcome by expanding the production of large animals alone, but rather by increasing the production of highly reproducing animals in the livestock unit. The goal of this study was to examine how adding pomegranate peel (PP), garlic powder (GP), or a mixture of the two to the diet of does affect their weight, the number of offspring, reproductive performance, hematological indices, and several antioxidants indicators as well as the liver and kidney functions. A total of 20 adult and mature female mixed rabbits at age 4.5–5 months and averaging 3.05 ± 0.63 kg body weight, were allocated into four experimental groups (n = 5). The first group was provided with the basal diet and was considered as control animals, while the second, third, and fourth groups were fed the basal diet supplemented with PP 3.0%, GP 3.0%, and a mixture of PP 1.5% + GP 1.5%, respectively. After 2 weeks of feeding the experimental diets, natural mating with untreated bucks was carried out. The kits were weighed immediately after parturition, and then every week. The study found that rabbits fed with 3% PP led to a 28.5% increase in the number of kits at birth compared to the control group. As an effect of supplementing PP 3%, GP 3%, and PP 1.5% + GP 1.5%, the birth weight increased by 9.2%, 7.2%, and 10.6%, respectively, as compared to the control. Hemoglobin increased significantly in all treatment groups as compared to the control at the age of kit weaning. Lymph cells increased significantly in the rabbits that were fed with GP (3%) than in other groups and even the control. The results showed that creatinine levels were significantly decreased in the PP (3%) and GP (3%) than in control rabbits. The level of triglycerides significantly declines in groups treated with PP (3%) than in other treatment groups and the control. The addition of PP 3% or GP 3% increased the progesterone hormone. The addition of PP 1.5%+GP 1.5% improved the immunoglobulin IgG. The results of superoxide dismutase, catalase, glutathione, and total antioxidant capacity showed a significant decline in groups treated with GP (3%) than other treated groups. In conclusion, pomegranate is a promising substance to include in a rabbit’s diet, followed by garlic to boost reproductive efficiency.

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Antioxidant and anti-apoptotic potential of whole-pomegranate extract promoted growth performance, physiological homeostasis, and meat quality of V-line rabbits under hot summer conditions

Cited by 12 publications

References 53 publications

Impact of Fennel Essential Oil as an Antibiotic Alternative in Rabbit Diet on Antioxidant Enzymes Levels, Growth Performance, and Meat Quality

Impact of Fennel Essential Oil as an Antibiotic Alternative in Rabbit Diet on Antioxidant Enzymes Levels, Growth Performance, and Meat Quality

Use of zinc oxide nanoparticles in the growing rabbit diets to mitigate hot environmental conditions for sustainable production and improved meat quality

Effect of Feeding Pomegranate (Punica granatum) Peel and Garlic (Allium sativum) on Antioxidant Status and Reproductive Efficiency of Female Rabbits

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