Antioxidant and Anti-Inflammatory Activity of Artemisia campestris L.

Abstract

This work focuses on a qualitative and quantitative study of some secondary metabolites of the species Artemisia campestris growing in the region of El Bayadh_Algeria. Accordingly, the total polyphenol content of the leaves is (89.12 ± 0.12 mg GAE / g) followed by stems and roots (85.11 ± 4.78 mg GAE / g) and (82.78 ± 4, 78 mg GAE / g) respectively. Moreover, the flavonoids content is also very high (119.12 ± 0.22 mg EC / g) for the leaves, (110.61 ± 0.09 mg EC / g) for the stems, and (105.71 ± 0.26 mg EC / g) for the roots. Therefore, the scavenger potential of free radicals of this species is very high. Henceforth, the classification of the three organs according to the DPPH test and the β-carotene bleaching test in descending order is leaves> stems> root. Thus, carrageenan in mice induced a remarkable anti-inflammatory dose-effect (600 mg/kg) recorded with an 82% inhibition of plantar edema.