Antioxidant and antiacetylcholinesterase activities of Sorbus torminalis (L.) Crantz (wild service tree) fruits

Hasbal, Gozde; Yilmaz-Ozden, Tugba; Can, Ayşe

doi:10.1016/j.jfda.2014.06.006

Cited by 42 publications

(45 citation statements)

References 33 publications

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“…Nowadays, the search for new sources of effective acetylocholinoesterase inhibitors for the treatment of neurodegenerative disorders such as Alzheimer's disease is extremely important, as acetylcholinesterase catalyzes hydrolysis of a neurotransmitter acetylcholine that terminates signaling events across cholinergic synapses, including those of neuromuscular functions. Some studies suggest that dietary supplements with antioxidants and free radical scavengers may display benefits in slowing the mild cognitive impairment of Alzheimer's disease [49]. Our results for anti-AChE enzymes were similar, and the roots of D. fullonum L. exhibited stronger inhibitory effect against AChE than leaves (47.14 ± 0.05 vs. 43.89 ± 0.03%, respectively).…”

Section: Antioxidant and Antiacetylcholinesterase Activitysupporting

confidence: 72%

“…Therefore, we suppose the observed effects were due to phenolic acids or iridoids or other chemical constituents, including triterpene saponins and alkaloids identified in the roots of D. asper [15]. Other research [49] also shows that many plants rich in natural antioxidants have been proposed as alternative therapeutic agents for Alzheimer's disease. Ji et al [26] showed that some iridoids isolated from the roots of D. asper exhibited a moderate neuroprotective activity against Aβ 25-35 -induced cell death in PC12 cells.…”

Section: Antioxidant and Antiacetylcholinesterase Activitymentioning

confidence: 92%

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Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities

Oszmiański

Juszczyk

Nowicka

2020

Plants

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The aim of the study was to identify and evaluate the content of iridoids and phenolic compounds in the leaves and roots of Dipsacus fullonum L. They were identified and quantified by UPLC-PDA-MS/MS. Five iridoid compounds (loganic acid, loganin, sweroside, cantleyoside, and sylvestroside III) were identified in Dipsacus fullonum L. leaves and roots. Seven phenolic acids and three flavones were identified in the leaves, and seven phenolic acids were detected in the roots. The leaves contained more iridoids and phenolic compounds than the roots. We also evaluated the antimicrobial (anti-bacterial and anti-yeast), antioxidant (ORAC methods), and antiacetylcholinesterase (AChE) activities of Dipsacus fullonum L. leaves and roots. Leaf extract demonstrated the strongest antioxidant activity, but roots showed stronger antiacetylcholinesterase activity than leaves. The study also confirmed antibacterial activity of root-derived compounds against Staphylococcus aureus DSM 799 and Escherichia coli ATCC 10536.

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Section: Antioxidant and Antiacetylcholinesterase Activitysupporting

confidence: 72%

Section: Antioxidant and Antiacetylcholinesterase Activitymentioning

confidence: 92%

Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities

Oszmiański

Juszczyk

Nowicka

2020

Plants

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“…When compared with other fruit species, Sorbus fruits have higher or similar antioxidative activity like plums, which have 5.87 to 29.19 mM trolox/kg (Kaulmann and others ) or other different fruit species 0.58 to 15.57 mM Trolox/kg (Chen and others ). It has been reported that Sorbus fruits could contribute to the health advantages in the everyday diet, due to its antioxidant possessions and nutrients (Hasbal and others ).…”

Section: Resultsmentioning

confidence: 99%

Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes

Mikulič-Petkovšek

Krška

Kiprovski

et al. 2017

Journal of Food Science

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In this study, biochemical profile of fruits of 9 Sorbus genotypes was analyzed. The content of total sugars ranged from 69.7 g/kg ('Titan') to 217.5 g/kg (Sorbus torminalis) and total organic acids from 17.7 g/kg ('Businka') to 40.2 g/kg (S. torminalis). The highest content of total anthocyanins had 'Burka' (871 mg/kg FW) and 'Businka' (856 mg/kg FW). Quercetin derivatives represented more than 95% of total flavonols. 'Alaja krupnaja' had 3.5- to 29-fold higher rutin content than other analyzed genotypes. S. torminalis fruits had the greatest diversity of isorhamnetin and kaempferol derivatives. Chlorogenic acid was the major hydroxycinnamic acid and its share was 33% to 73% of total analyzed hydoxycinnamic acid derivatives. The richest in chlorogenic acid were 'Krasavica' and 'Alaja krupnaja' fruits. Cultivar 'Businka' had the highest content of epicatechin (40.7 mg/kg) and neochlorogenic acid (1061 mg/kg). Different procyanidin oligomers were detected among flavanols in Sorbus fruits. The highest content of total flavanols was measured in 'Alaja Krupnaja' fruits. Cultivars 'Krasavica' (84.5 mg/kg) and 'Burka' (85.1 mg/kg) had 1.2- to 6.9-fold higher amount of total carotenoids. 'Businka' was highlighted as the richest in total tannin and phenolic contents (3768 mg GAE/kg) and consequently, it had the highest antioxidant activity (57.6 mM TE/kg FW). Being abundant in polyphenolics, some extracts of Sorbus genotypes, for example, 'Businka,' 'Burka,' and 'Alaja krupnaja' could serve as valuable resource of bioactive compounds to food and pharmaceutical industries.

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“…Another study on Sorbus torminalis species [27] found 19150 mg/kg GAE total methanolextractable phenolic compounds, in frozen fruits.…”

Section: Methodsmentioning

confidence: 96%

Carotenoids, Flavonoids, Total Phenolic Compounds Content and Antioxidant Activity of Indigenous Pyracantha coccinea M. Roem. Fruits

Popoviciu¹,

Motelică²,

Negreanu–Pîrjol³

2020

Rev. Chim.

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Scarlet/red firethorn, Pyracantha coccinea M. Roem., is a common ornamental shrub, commonly cultivated nowadays in Romania and many other countries, in gardens or hedges. The tree has small white flowers and it produces small bright colored berries. The fruit is bitter and astringent, making it inedible when raw. The fruit can be cooked to make jellies, jams, sauces and marmalade. In this study, the Pyracantha coccinea M. Roem fruits from three common cultivars named �Orange Glow�, �Red Column� and �Soleil d�Or�, were collected from different individuals in Constanta city, Romania. Both frozen and dried (80�C) fruits were analyzed for the active principles content such as, carotenoids, flavonoids and total phenolic compounds correlated with antioxidant activity. Carotenoids were determined by acetone extraction and UV-Vis spectrophotometry, flavonoids, by methanol extraction and UV-Vis spectrophotometry and total phenolic, by methanol extraction, Folin-Ciocalteu reaction and UV-Vis spectrophotometry. The total antioxidant capacity was quantified through photochemiluminescence method by comparison with the standard substance used for calibration, Trolox� as tocopherol analogue (ACL procedure) using Photochem apparatus, Analytik Jena AG, Germany. The average carotenoid content in fresh frozen fruits ranged between 278-545 mg/kg (dry weight equivalent), while in dry material 133-203 mg/kg. Total flavonoids averaged 1415-4953 mg/kg in fresh fruits, increasing after heat-drying to 2981-5759 mg/kg. Fresh fruits contained a total amount of phenolic compounds of 11501-21107 mg/kg DW gallic acid equivalent, while dry fruits averaged 5749-8261 mg/kg GAE. Pyracantha coccinea M. Roem. fruits emphasized an increased antioxidant activity correlated with a high content of potentially bioactive compounds, especially of phenolic compounds, both in frozen and heat-dried state. �Red Column� and �Orange Glow� are the most promising varieties of the three cultivars, for potential pharmaceutical applications.

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Antioxidant and antiacetylcholinesterase activities of Sorbus torminalis (L.) Crantz (wild service tree) fruits

Cited by 42 publications

References 33 publications

Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities

Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities

Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes

Carotenoids, Flavonoids, Total Phenolic Compounds Content and Antioxidant Activity of Indigenous Pyracantha coccinea M. Roem. Fruits

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