2012
DOI: 10.1016/s1995-7645(12)60042-x
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Antioxidant and antiangiogenic activities of the essential oils of Myristica fragrans and Morinda citrifolia

Abstract: Bioactive compound(s) will be isolated from the nutmeg essential oil to be developed as antiangiogenic drugs.

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Cited by 63 publications
(45 citation statements)
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“…The results agree with the findings of the other researchers [34] in which the antioxidant activity of methanol extract of B. diffusa was reported due to the presence of rotenoids (boeravinone G, H and D). Among the rotenoids, boeravinone G plays the major role which is also a polyphenolic compound [34][35][36][37][38][39] .…”
Section: Discussionmentioning
confidence: 99%
“…The results agree with the findings of the other researchers [34] in which the antioxidant activity of methanol extract of B. diffusa was reported due to the presence of rotenoids (boeravinone G, H and D). Among the rotenoids, boeravinone G plays the major role which is also a polyphenolic compound [34][35][36][37][38][39] .…”
Section: Discussionmentioning
confidence: 99%
“…A large body of evidences point to glycation as a key molecular basis of diabetic complications. The fact that glycoxidative reactions cause protein dysfunction strongly suggests a role for such reactions as pathogenic factors in diabetes [30][31][32][33][34][35][36][37][38][39] . AGEs contribute to diabetic complications through a series of pathological changes such as increased atherogenicity of LDL, increased basement membrane permeability and decreased insulin binding to its receptors.…”
Section: Discussionmentioning
confidence: 99%
“…A significant (p<0.01 and <0.001) increase in reduced glutathione (GSH, the vital biological defence molecule against oxidative damage) in liver was reported in this study, in comparison to radiation alone group at day 1, 3, 7, 15 and 30 following irradiation. Some of the recent works (Akinboro et al, 2011;Piaru et al, 2012) further supported the antioxidant property of nutmeg.…”
Section: Myristica Fragransmentioning
confidence: 86%
“…(Family: Myristicaceae) have been reported to possess various beneficial properties including anti-inflammatory, hepatoprotective and anticancer activities (Morita et al, 2003;Eklund et al, 2005;Tajuddin et al, 2005;Chirathaworn et al, 2007;Piaru et al, 2012;Zhang et al, 2012;Thuong et al, 2013). In the antioxidant study , 10 mg/kg b.w.…”
Section: Myristica Fragransmentioning
confidence: 99%