Antioxidant and antibacterial effects of medicinal plants and their stick-type medicinal concentrated beverages

Chang, Hyeon‐Jun; Kim, Chongam; Kang, Yun-Hwan; Choi, Myunghwan; Lee, Jeung Hee

doi:10.1007/s10068-020-00793-9

Cited by 16 publications

(14 citation statements)

References 25 publications

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“…However, Kp has increasingly survived antibiotic treatment due to resistance or tolerance to the drugs. ( Chew et al, 2017 ; Hossan et al, 2018 ; Chang et al, 2020 ). Hence, ample research space exists for the development of an efficient treatment to control Kp infection ( Turan et al, 2018 ; Yang et al, 2018 ; Avgerinos et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Bergenin Monohydrate Attenuates Inflammatory Response via MAPK and NF-κB Pathways Against Klebsiella pneumonia Infection

et al. 2021

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Background:Klebsiella pneumonia has emerged as a critical pathogen causing severe clinical problems, such as pneumonia and sepsis. Meanwhile, intensified drug resistance induced by antibiotic therapy necessitates discovering novel and active molecules from Traditional Chinese Medicine (TCM) for treatment.Methods and results: In this study, the isolated Bergenin monohydrate showed an anti-inflammatory effect in Klebsiella-infected mice. We initially investigated the anti-inflammatory effects and cytoprotection against oxidative stress in vitro and in vivo. Interestingly, a specific dose of Bm can effectively ameliorate lung injury and suppress the expression of inflammatory cytokines such as TNF-α, IL-6, IL-1β and PEG2. Moreover, Bm was also shown to reduced the levels of MPO, MDA and increased SOD and GSH activities. Moreover, we assessed the intracellular signaling molecules including p38, ERK, JNK, IκB, NF-κB-p65 by western blotting and verified through MAPK and NF-κB pathways inhibition experiments. These results reveal that Bm executed its effects via the classical MAPK signaling pathway and NF-κB pathway.Conclusion: Given its underlying anti-inflammatory effect, Bm may be used as a promising therapeutic against Klebsiella-induced infection, thus providing a benefit for the future clinical therapy of pneumonia and medicine design.

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Section: Introductionmentioning

confidence: 99%

Bergenin Monohydrate Attenuates Inflammatory Response via MAPK and NF-κB Pathways Against Klebsiella pneumonia Infection

et al. 2021

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“…In another study, the phenolic molecules eugenol and its derivatives, which suppress the activity of the proinflammatory enzymes cyclooxygenase-2 (COX-2) and lipoxygenase (LOX), have been linked to Syzygium aromaticum's anti-inflammatory properties [10]. Plantamajoside, a hydroxycinnamic acid, in Plantago asiatica L. is a well-known polyphenolic molecule with anti-inflammatory properties, and ethanolic extracts of this plant suppressed the mRNA expression of pro-inflammatory mediators (IL-1, IL-6, iNOS, COX-2, and NF-B) in macrophages, inhibiting NO generation [11]. Another example is the lectins extracted from Canavalia brasiliensis seeds and Canavalia ensiformes seeds were found to have antidepressant efficacy through their interaction with serotoninergic (5-HT1A, 5-HT 2 receptors), noradrenergic (alpha 2 adrenoceptor), and dopaminergic (D 2 receptor) systems [12].…”

Section: Various Biological Activities Of Medicinal Plantsmentioning

confidence: 99%

A Review on the Antidiabetic Potential of Medicinal Plants

Bushnak¹,

Hajj²,

Jaber³

2021

SJMH

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Diabetes mellitus has long been seen as a substantial economic burden on patients, their families, and society. Impairment in blood sugar regulation has major health repercussions. Furthermore, untreated diabetes causes major chronic complications like blindness, renal failure, and heart failure, as well as an increase in associated mortality. New anti-diabetic medicines are being researched to help alleviate this issue. Conventional Anti-diabetic medications are beneficial, several synthetic drugs are available in the market to treat diabetes, but they are costly and come with inevitable adverse effects. Medicinal plants, on the other hand, may serve as an alternate source of anti-diabetic agents. According to the World Health Organization, 80 % of the population in underdeveloped nations still relies on traditional medicines or folk medicines, which are largely made from plants, for disease prevention or treatment. For instance, anti- proliferative, anti-viral, anti-inflammatory and anti-hyperglycemic effects. In order to find a natural anti-diabetic source that comes with less side effects, several studies have been conducted. The aim of this work is to review these studies and highlight the potential of plants when it comes to their anti-diabetic effect.

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“…The total phenolics contents (TPC) was measured using the Folin-Denis phenol method (Chang et al, 2020). In a test tube, 80% diluted ethanol extract (0.5 mL), Folin-Ciocalteu's phenol reagent (0.5 mL), and distilled water (4.5 mL) were mixed and reacted for 3 min.…”

Section: Analysis Of Total Phenolics and Flavonoid Contentsmentioning

confidence: 99%

“…The total flavonoid contents (TFC) was measured using the method described by Chang et al (2020). In a test tube, a diluted solution of 80% ethanol extract (1 mL) was mixed with distilled water (4 mL) and allowed to react for 5 min; then a 5% NaNO 2 solution (0.3 mL) and 10% AlCl 3 solution (0.3 mL) were added and reacted for 6 min.…”

Section: Analysis Of Total Phenolics and Flavonoid Contentsmentioning

confidence: 99%

Evaluation of the quality characteristics of protein cubes supplemented with moringa leaf (Moringa oleifera Lam.) and green tea powders

Baek¹,

Lee²

2021

Korean J. Food Preserv.

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The biological activities of moringa leaf and green tea powders were compared, and the quality characteristics of protein cubes supplemented with these powders (5% and 7.5%, respectively) were evaluated. The green tea powder had higher chlorophyll, essential fatty acid, total polyphenol (TPC), and flavonoid (TFC) contents than the moringa leaf powder. The green tea powder had higher levels of 2,2-diphenyl-1-picrylhydrazyl radical scavenging capacity (DPPH RSC), Trolox equivalent antioxidant capacity (TEAC), and ferric reducing antioxidant power (FRAP) than the moringa leaf powder, indicating higher antioxidant activity. The green tea powder inhibited the nitric oxide production to a greater extent than the moringa leaf powder. The protein cubes that were supplemented with either the moringa leaf or green tea powders had smaller volumes and were harder, chewier, and more easily fractured than the control protein cubes. The protein cubes supplemented with green tea powder had higher TPC and TFC, exhibited higher antioxidant activity (p<0.05), and had better sensory properties in terms of aroma, taste, and texture than the protein cubes supplemented with moringa leaf powder; however, the differences were not significant(p>0.05). The results of the present study indicate that green tea is a more suitable health-oriented functional additive than moringa leaf in the development of high-protein and nutrient-rich bakery products with high consumer acceptability as well as antioxidant and anti-inflammatory properties. Key words：antioxidant, green tea, Moringa oleifera, protein cube, quality characteristics

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Antioxidant and antibacterial effects of medicinal plants and their stick-type medicinal concentrated beverages

Cited by 16 publications

References 25 publications

Bergenin Monohydrate Attenuates Inflammatory Response via MAPK and NF-κB Pathways Against Klebsiella pneumonia Infection

Bergenin Monohydrate Attenuates Inflammatory Response via MAPK and NF-κB Pathways Against Klebsiella pneumonia Infection

A Review on the Antidiabetic Potential of Medicinal Plants

Evaluation of the quality characteristics of protein cubes supplemented with moringa leaf (Moringa oleifera Lam.) and green tea powders

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