Antioxidant and antimicrobial activities of Saraca thaipingensis Cantley ex Prain

Prachayasittikul, Supaluk; Worachartcheewan, Apilak; Yainoy, Sakda; Lomchoey, Natthakaln; Kittiphatcharin, Paveena; Ruchirawat, Somsak; Prachayasittikul, Virapong

doi:10.1016/s2221-1691(12)60315-3

Cited by 6 publications

(7 citation statements)

References 7 publications

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“…Compound 2 is a known phytosterol found in soy beans and other plant species i.e., Hydnophytum formicarumJack. (Rubiaceae) (Prachayasittikul et al, 2008), S. acmella Murr. (Prachayasittikul et al, 2009), P. debilis (Prachayasittikul et al, 2009), Saraca thaipingensis Cantley ex Prain (Leguminosae) (Prachayasittikul et al, 2012) and Pterocarpus indicus Willd (Leguminosae) .…”

Section: Discussionmentioning

confidence: 99%

“…(Rubiaceae) (Prachayasittikul et al, 2008), S. acmella Murr. (Prachayasittikul et al, 2009), P. debilis (Prachayasittikul et al, 2009), Saraca thaipingensis Cantley ex Prain (Leguminosae) (Prachayasittikul et al, 2012) and Pterocarpus indicus Willd (Leguminosae) . Biological activity results of E. prostrata showed that the plant extracts (chloroform and ethyl acetate) displayed antifungal activity against S. cerevisiae ATCC 2601 (MIC = 256 g/mL), but not showed antibacterial activity.…”

Section: Discussionmentioning

confidence: 99%

“…The DPPH (a stable purple color radical) reacts with an antioxidant to form a light-yellow colored of diphenylpicrylhydrazine, the reduced product that can be spectrophotometrically detected. The assay (Prachayasittikul et al, 2012) was initiated by adding 1 mL solution of DPPH in methanol (0.1 mM) to a sample solution (0.45 mL, 1 mg/mL dissolved in DMSO). The reaction mixture was incubated for 30 min in a dark 100 .…”

Section: Antioxidant Assaymentioning

confidence: 99%

“…Cytotoxic assay was performed using the modified method as previously described (Prachayasittikul et al, 2008). Briefly, the confluent cell monolayers were trypsinized and diluted with appropiate culture medium to a final concentration of 3×10 5 cells/mL.…”

Section: Cytotoxic Assaymentioning

confidence: 99%

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Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn.

Cherdtrakulkiat¹,

Boonpangrak²,

Pingaew³

et al. 2015

J App Pharm Sci

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Bioactive triterpenoids; 3-acetylaleuritolic acid, stigmasterol, a mixture of triterpenoids, fatty esters and aromatic components were isolated from the aerial parts of Eclipta prostrata by column chromatography. The plant extracts were investigated for their antimicrobial activity (agar dilution method) against twenty-eight strains of gram-positive and gram-negative bacteria, including diploid fungus. In addition, antioxidant and cytotoxic activities were also evaluated. The extracts and isolated fractions exhibited antimicrobial activity against Morexella catarrhalis, Corynebacterium diphtheriae NCTC 10356 and Streptococcus pyogenes with the MIC of 64 g/mL including Saccharomyces cerevisiae ATCC 2601 (MIC 256 g/mL). The ethyl acetate extract and isolated fractions displayed antioxidant effect. In addition, the plant extracts showed cytotoxic activity (ED50 > 100 g/mL) toward HuCCA-1 and KB cells. The results demonstrate beneficial effects of E. prostrata as the antimicrobials and bioactive compounds for medicinal usages.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Antioxidant Assaymentioning

confidence: 99%

Section: Cytotoxic Assaymentioning

confidence: 99%

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Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn.

Cherdtrakulkiat¹,

Boonpangrak²,

Pingaew³

et al. 2015

J App Pharm Sci

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“…Medicinal plants with antioxidant and anticancer (Li et al, 2007;Charoensin, 2014); and with anticancer and antimicrobial (Tamokou et al, 2013) activities have been reported. In addition, a variety of medicinal plants have been documented to exert dual actions as antimicrobials and antioxidants (Prachayasittikul et al, 2008(Prachayasittikul et al, , 2009(Prachayasittikul et al, , 2010(Prachayasittikul et al, , 2012Treeratanapiboon et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial, antioxidant and anticancer activities of <i>Strychnos lucida</i> R. Br.

Sarmento¹,

Worachartcheewan²,

Pingaew³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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Backgroud: Strychnos lucida R. Br. (Loganiaceae), a well-known indigenous medicine in Timor Leste, has been used for the treatment of ailments such as malaria, diarrhoea, fever, hypertension, cancer, diabetes mellitus and skin infections. Its pharmacological activity has never been reported. The aim of this study was to determine the biological activities of S. lucida, including antimicrobial, antioxidant and anticancer activities. Materials and methods:The stem, stem bark, twig and leaves of S. lucida were extracted by non-polar (hexane) and polar (ethyl acetate and methanol) solvents. Antimicrobial activity of the plant extracts against 29 microorganisms was evaluated using the agar dilution method and antioxidant properties were determined using DPPH and SOD assays. Anticancer activity was investigated against HepG2, HuCCA-1, A549 and MOLT-3 cell lines using the MTT and XTT assays. Results: It was found that the hexane and ethyl acetate extracts of S. lucida selectively inhibited the growth of Gram positive bacteria (Bacillus subtilis ATCC 6633, Bacillus cereus and Streptococcus pyogenes) with MICs range of 32-128 g/mL. Antioxidant activities, radical and superoxide scavenging properties, were observed for ethyl acetate and methanol extracts of S. lucida. Particularly, the ethyl acetate extracts selectively showed inhibitory activity against MOLT-3 cells. Notably, the plant extracts showed the relationship between antimicrobial, antioxidant and anticancer activities. Conclusion:The findings support the medicinal usage of S. lucida.

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Medicinal plants as a potential source of Phosphodiesterase-5 inhibitors: A review

Ganapathy

Priya

Kumaran

2021

Journal of Ethnopharmacology

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Antioxidant and antimicrobial activities of Saraca thaipingensis Cantley ex Prain

Cited by 6 publications

References 7 publications

Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn.

Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn.

Antimicrobial, antioxidant and anticancer activities of <i>Strychnos lucida</i> R. Br.

Medicinal plants as a potential source of Phosphodiesterase-5 inhibitors: A review

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