Antioxidant and antitumour activities of extracts from Patrinia villosa and its active constituents

Lei, Jiachuan; Yang, Yuan; Zhang, Wu; Yu, Jianqing

doi:10.1016/j.jff.2015.04.037

Cited by 15 publications

(6 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The isolated compounds from Patrinia villosa extract include resorcinol. It was found that resorcinol exhibited a moderate level of DPPH radical-scavenging activity with IC50 of 171.2 ± 1.9 µg/ml [35]. In addition, the GC-MS analysis of Foeniculum vulgare var.…”

Section: Gc-ms Analysis Of H Glabra Warb Seedsmentioning

confidence: 99%

Nutrition Composition and Analysis of Medicinal Herbal Potential of Horsfieldia glabra Warb. Seeds

Chaichana

2015

KMUTNB: IJAST

View full text Add to dashboard Cite

Horsfieldia glabra Warb. is a locally consumed plant indigenous to Chiang Rai Province, Thailand and of late, there has been considerable interest in evaluating its health benefits. The aim of this study was to investigate H. glabra Warb. seeds in order to assess their nutritional properties and its potential as a medicinal herb. In terms of nutritional assessment, the experiment found that H. glabra Warb. seed extract contained 68.24 g per 100 g dry weight of lipids, 7.80 g per 100 g dry weight of protein, 14.20 g per 100 g dry weight of carbohydrates, 5.04 g per 100 g dry weight of crude fiber, 1.41 g per 100 g dry weight of ash and 6.827 kcal per 1 g dry weight of energy. The analysis of its potential as a medicinal herbal determined the antioxidant activity and Minimum Inhibitory Concentration (MIC) of Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. The results revealed that H. glabra Warb. seed extraction displayed antioxidant activity (62.01 ± 3.99% DPPH inhibition activity) with a IC50 value of 0.358 ± 0.02 mg/ml. Experiments investigating MIC determined that the extract exhibited the minimum inhibitory concentration of S. aureus (15.625 mg/ml) with 8.00 ± 1.73 mm clear zone. Whereas Streptomycin concentration of 30 mg/ml inhibited 9.00 ± 2.00 mm clear zone. GC-MS analysis of H. glabra Warb. seeds determined that the major compounds were α-resorcinol (40.769%) and 4-vinylphenol (23.761%).

show abstract

Section: Gc-ms Analysis Of H Glabra Warb Seedsmentioning

confidence: 99%

Nutrition Composition and Analysis of Medicinal Herbal Potential of Horsfieldia glabra Warb. Seeds

Chaichana

2015

KMUTNB: IJAST

View full text Add to dashboard Cite

show abstract

“…This well‐known herb was thought to be non‐toxic and could be used to clear heat and eliminate blood stasis (He et al, ). Modern pharmacology suggests that PVJ possesses the effects of antitumor (Sheng, Yang, Zhang, & Li, ), anti‐inflammation (Zheng et al, ), hepatoprotective activity (Jiang, Huang, Yang, & Zhang, ) among others (Lei, Yang, Yang, Zhang, & Yu, ). Of these, flavonoids (Liao et al, ), iridoids (Daiet et al, ) and terpenoids are the main effective components of genus Patrinia.…”

Section: Introductionmentioning

confidence: 99%

Analysis of plasma migration components in Patrinia villosa (Thunb.) Juss. effective parts by UPLC–Q‐TOF–MS

Han

Wang

Yang

et al. 2019

Biomedical Chromatography

View full text Add to dashboard Cite

Patrinia villosa (Thunb.) Juss. (PVJ) is described as pungent, bitter and slightly cold in Chinese medicine, and is associated with the large intestine, stomach and liver meridians. The preliminary experiments of our research team proved that PVJ total flavonoids have excellent inhibitory effects on liver cancer cells. The present experiment uses the UPLC–Q‐TOF–MS technology and serum pharmacochemistry methods to analyze the chemical components in vitro and in vivo of PVJ antiliver tumors. A total of 14 chemical components were identified in the total flavonoids extract of PVJ, and it is mainly composed of flavonoids, flavonones, flavonols and phenolic acids. At the same time, seven prototypical components and seven metabolic components were detected in the drug‐containing plasma. Hydrocaffeate and scutellarein are the phase I metabolites of caffeic acid and scutellarin, respectively. Sulfated apigenin, sulfated luteolin, sulfated kaempferol and methylated kaempferol are the II phase metabolites of apigenin, luteolin, kaempferol, respectively. The experiment provides a reference for the research and development of antitumor drug candidates, and provides a basis for revealing the bioactive components of PVJ and the antitumor mechanism.

show abstract

“…The most distinctive endemic food plant is Patrinia villosa, which is a traditional medicine well-known for its anti-inflammatory, antitumor, and antibacterial properties. [37][38][39][40] This species tastes extremely bitter and it has the unpleasant foot odor, but its young shoot (Figure 2a) is a popular vegetable in Meizhou City, Guangdong Province. Patrinia villosa is under large-scale cultivation with a relatively high price (¥5/ kg for fresh weight [FW]; ¥60/kg for dry weight [DW]).…”

Section: Food-medicine Plant Species In the Study Areasmentioning

confidence: 99%

Nutritional and Functional Properties of Wild Food-Medicine Plants From the Coastal Region of South China

Liang

Wang

et al. 2020

J Evid Based Complementary Altern Med

View full text Add to dashboard Cite

Food-medicine plants play an important role in providing nutrition and treating chronic diseases, especially in many minority communities and developing regions. The coastal region of South China has abundant resources of medicinal plants. A long history of crosscultural medicinal practices among different minority groups has facilitated the development of a remarkable dietary culture by using food-medicine plants. However, integrative ethnobotanical research on both nutritional and functional properties of the foodmedicine plants in this region is still limited. In this study, 27 commonly used wild food-medicine plants were recorded and analyzed from the coastal region of South China. Most of them are good sources for calcium (47.83-1099.89 mg/100 g fresh weight), dietary fiber (3.00-31.87 mg/100 g fresh weight), iron (1.17-24.73 mg/100 g fresh weight), and vitamin C (0.44-68.32 mg/100 g fresh weight). Solanum americanum has the highest average nutritive value and is also considered to be good sources for proteins (7.90 g/100 g fresh weight). Medicinal properties of the studied species can be classified into 8 categories: treatment of the damp-heat syndrome, digestive diseases, urologic diseases, arthropathy, respiratory diseases, gynecological diseases, snake or insect bites, and uses as a tonic. Treating the damp-heat syndrome or expelling warm pathogenic factors is the most commonly used ethnomedicinal practice in the study area. The present study highlights that the local ethnomedicinal practices are deeply influenced by local natural conditions and customs. Foodmedicine plants with superior key nutrients have been used regularly in the diet as medicinal food to alleviate common endemic diseases.

show abstract

Antioxidant and antitumour activities of extracts from Patrinia villosa and its active constituents

Cited by 15 publications

References 42 publications

Nutrition Composition and Analysis of Medicinal Herbal Potential of Horsfieldia glabra Warb. Seeds

Nutrition Composition and Analysis of Medicinal Herbal Potential of Horsfieldia glabra Warb. Seeds

Analysis of plasma migration components in Patrinia villosa (Thunb.) Juss. effective parts by UPLC–Q‐TOF–MS

Nutritional and Functional Properties of Wild Food-Medicine Plants From the Coastal Region of South China

Contact Info

Product

Resources

About