Antioxidant and detoxification responses of oysters <i>Crassostrea hongkongensis</i> in a multimetal‐contaminated estuary

Li, Xuan; Wang, Wen‐Xiong

doi:10.1002/etc.3455

Cited by 24 publications

(7 citation statements)

References 55 publications

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“…Nevertheless, in another study the GST activity did not change when mussels M. galloprovincialis were exposed to a similar range of Cu concentrations for 7 days (Maria and Bebianno, 2011) although the inductive effect of Cu could be observed at the level of GST protein expression (Maria et al, 2013). Noteworthy, increased GST activity was also reported for bivalves from metal-polluted marine environments (Fernández et al, 2010;Liu and Wang, 2016;Vidal-Liñán et al, 2014a).…”

Section: Discussionmentioning

confidence: 91%

The effect of copper and chlorpyrifos co-exposure on biomarkers in the marine mussel Mytilus galloprovincialis

Perić

Burić

2019

Chemosphere

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Metals and organophosphorous pesticides commonly co-occur in marine environment, but the effect of their mixtures on non-target organisms is still poorly understood. This study investigated the combined effect of the essential metal copper (Cu) and organophosphorous pesticide chlorpyrifos (Chp) in mussels Mytilus galloprovincialis after short-term exposure to their sublethal concentrations. Mussels were exposed for four days to 5 and 15 µg l -1 Cu and 0.05 and 5 µg l -1 Chp, and to their binary mixtures. The investigated biomarkers, namely acetylcholinesterase activity (AChE), glutathione S-transferase activity (GST), metallothioneins content (MTs) and lipid peroxide levels (LPO) displayed unspecific and inconsistent response patterns that varied depending on the concentration of chemicals and composition of mixtures. The exposure to Cu or Chp alone did not induce AChE activity changes, whereas only Cu provoked a significant GST activity increase. Exposure to lower and higher concentration of Chp resulted in MTs content and LPO level increase, respectively.Response of biomarkers to mixtures was generally inconsistent. Data integration by IBR index and PCA revealed different stress levels for given exposure conditions, but no explicit differentiation between single and joint exposures was found. The present results showed that low and environmentally relevant concentrations of Cu and Chp in mixtures may result in a detectable biological response, stressing the need for further investigation of joint effects of widespread marine contaminants in sentinel organisms.

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Section: Discussionmentioning

confidence: 91%

The effect of copper and chlorpyrifos co-exposure on biomarkers in the marine mussel Mytilus galloprovincialis

Perić

Burić

2019

Chemosphere

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“…The discrepancy between the high expression of NT, as an indicator of the oxidant peroxynitrite generation, and the low detection of MDA, as an indicator of the lipid peroxidation, may rely on the protective effect of the antioxidant systems that prevents cell oxidative damage (Canesi, 2015; Ferreira et al, 2019; Liu & Wang, 2016). In this sense, the limited efficiency of the antioxidant defences and the increased level of lipid peroxidation may have been associated with oyster mortality events (Gènard et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Section: Ta B L E 1 Monthly Prevalence Ofmentioning

confidence: 99%

Crassostrea gigas (Thunberg 1793) cultivation in southern Adriatic Sea (Italy): A one‐year monitoring study of the oyster health

Mosca

Tiscar

Hattab

et al. 2021

Aquaculture Research

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Pacific oyster (Crassostrea gigas) farming has developed in recent years along the Italian coasts of the Adriatic sea. This is particularly true in sites located in the northern area and only recently becoming more common in the southern area, which is different particularly in regards to temperature and trophic conditions. There is a lack of studies on the status of the oysters farmed in this area; therefore, the present research aimed to monitor the health conditions of adult triploid oysters that were kept in offshore longline culture system over one year. Environmental parameters were daily estimated from satellite. Biometric, immunological and oxidative stress parameters were measured monthly, looking also for the presence of pathogens, such as OsHV‐1, Vibrio aestuarianus and Vibrio splendidus. During summer months, high temperatures and low food availability had a detrimental impact on the growth and immunological parameters which showed a progressive recovery during the autumn and winter months. Overall, no abnormal mortality was observed, and no histological alterations were evident. The presence of pathogens was negligible, and the oxidative stress parameters were poorly detected, except for the digestive glands during the autumn and winter seasons. On this basis, the data herein reported suggest that the area could be suitable for the development of triploid Pacific oyster farming, although animals would require a longer time to reach commercial size.

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“…Exposure to water‐borne copper negatively affects bivalve gills’ antioxidant/detoxifying response. For example, Regoli & Principato (1995) have shown inhibition of GST activity in Mytilus galloprovincialis exposed in the laboratory to Cu 2+ , whereas the gills of the oyster Crassostrea hongkongensis accumulated Cu 2+ and showed increased GST activity and lipid peroxidation (Liu & Wang, 2016). In the freshwater bivalve Unio tumidus , Doyotte et al (1997) have observed that exposure to water‐borne Cu 2+ diminished gill antioxidant defenses, except for CAT, and increased lipid peroxidation.…”

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Copper and Escherichia coli Challenge on the Immune Response and Gill Oxidative Balance in the Freshwater Mussel Diplodon chilensis

Castro

Bianchi

Felici

et al. 2022

Enviro Toxic and Chemistry

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Copper is a water and sediment pollutant that can be biomagnified by phytoplankton, and it often co‐occurs with fecal bacteria. We addressed the combined effects of copper and Escherichia coli on the immune response and gill oxidative balance of the freshwater mussel Diplodon chilensis. Bivalves were sorted into four groups fed with 1) control algae, 2) bacteria (E. coli), 3) copper‐enriched algae (Cu2+) algae, and 4) copper‐enriched algae followed by bacteria (Cu2+ + E. coli). Cellular and humoral immune and cytotoxic variables were analyzed in hemolymph, and detoxifying/antioxidant enzyme activities (glutathione S‐transferase [GST] and catalase [CAT]) and lipid peroxidation (thiobarbituric acid reactive substances [TBARS]) were studied in gill tissue. The total hemocyte number increased after Cu2+ exposure, independently of the E. coli challenge. The proportion of hyalinocytes significantly diminished in the E. coli and Cu2+ groups but not in Cu2+ + E. coli groups; granulocytes significantly increased with E. coli but not with Cu2+ + E. coli treatments. Phagocytic activity was higher in all treatments than in control mussels. Acid phosphatase activity was increased by E. coli and inhibited by Cu2+ and Cu2+ + E. coli. Both E. coli and Cu2+ but not Cu2+ + E. coli augmented alkaline phosphatase activity. The Cu2+ and Cu2+ + E. coli treatments reduced the lysosomal membrane stability and cell viability. Humoral bacteriolytic and phenol oxidase activities were not affected by any treatment. The Cu2+ treatment induced gill CAT and GST activities and increased TBARS levels. The Cu2+ + E. coli treatment reversed this CAT and GST stimulation and increased the Cu2+ effect on TBARS. Dietary Cu2+ affects bivalves' immunological and oxidative status and impairs defensive responses against bacteria. In turn, E. coli potentiates the gill oxidative effects of Cu2+. Environ Toxicol Chem 2023;42:154–165. © 2022 SETAC

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Antioxidant and detoxification responses of oysters Crassostrea hongkongensis in a multimetal‐contaminated estuary

Cited by 24 publications

References 55 publications

The effect of copper and chlorpyrifos co-exposure on biomarkers in the marine mussel Mytilus galloprovincialis

The effect of copper and chlorpyrifos co-exposure on biomarkers in the marine mussel Mytilus galloprovincialis

Crassostrea gigas (Thunberg 1793) cultivation in southern Adriatic Sea (Italy): A one‐year monitoring study of the oyster health

Effects of Dietary Copper and Escherichia coli Challenge on the Immune Response and Gill Oxidative Balance in the Freshwater Mussel Diplodon chilensis

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