Antioxidant and free radical scavenging activity of methanol extract of chungkukjang

Shon, Mi-Yae; Lee, Jun; Choi, Jehun; Choi, Sun-Young; Nam, Sanghae; Seo, Kwon‐Il; Lee, Sang‐Won; Sung, Nak‐Ju; Park, Seok-Kyu

doi:10.1016/j.jfca.2006.08.003

Cited by 61 publications

(41 citation statements)

References 31 publications

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“…Soya isoflavones like genistein and daidzein have been reported to have inhibitor y ffect on the breakage of DNA induced by hydrogen peroxide [20] 0 . Reports are available on increase in polyphenols of soya fermented foods [2,18,[20][21]. In the present study it was found that there was increase in both TPC and TFC in the fermented food as compared to raw materials (Table 3).…”

Section: Total Phenolic and Flavonoid Contentsupporting

confidence: 58%

Nutritional Assessment and Molecular Identification of Microorganisms from Akhuni/Axone: A Soybean Based Fermented Food of Nagaland, India

Deb

Jamir

2018

JAB

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Bendangnaro Jamir 1 and Chitta Ranjan Deb 2 * Department of Botany, Nagaland University, Lumami 798627, Nagaland, India rona.jamir@gmail.com, debchitta@rediffmail.com AbstractSoybean based fermented foods are known to be highly nutritive, not just because it contains high protein content but also due to presence of polyphenols. Various microorganisms involved during the fermentatio n process have proven to play active role in the enhancement of the nutritional value as well as increase in phytochemicals in the product. Akhuni/Axone is a popular soybean product of Nagaland, India. It forms an integral part of the diet and is used as a condiment during preparation of various dishes in the Naga kitchen. This study describes the nutritional value, the antioxidant activity and the presence of polyphenols of Akhuni/Axone, which increase significantly in composition between the soybean seeds and the fermented product. The molecular identification of the microorganisms present in Akhuni/Axone product is also reported in this paper.

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Section: Total Phenolic and Flavonoid Contentsupporting

confidence: 58%

Nutritional Assessment and Molecular Identification of Microorganisms from Akhuni/Axone: A Soybean Based Fermented Food of Nagaland, India

Deb

Jamir

2018

JAB

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“…The cytotoxic nature of aflatoxins may underlie increased MDA [24][25][26]. Increased lipid peroxidation (LOP) is reported in kidney of mice treated with aflatoxin B1 [27].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Nephrotoxic Effects of Aflatoxins on Common Carp (Cyprinus carpio)

Taheri

Banaee

Haghi

et al. 2017

IJT

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“…During fermentation of CGJ, the conversion of isoflavone b-glycosides to aglycones in soybean increases, leading to an increase in biological activities. 27 Microbial sources have been shown to be a potential means of producing natural antioxidants in fermented products. 28 In the present study, high-performance liquid chromatography analyses of daidzein and other compounds of interest in CGJE revealed the presence of aglycones, such as daidzein and genistein at high concentrations ( Supplementary Fig.…”

Section: Figmentioning

confidence: 99%

CheonggukjangEthanol Extracts Inhibit a Murine Allergic Asthma via Suppression of Mast Cell-Dependent Anaphylactic Reactions

Bae

Shin

See

et al. 2014

Journal of Medicinal Food

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Cheonggukjang (CGJ), a traditional Korean fermented soybean food, exerts immunomodulatory effects. Asthma is the most common chronic allergic disease to be associated with immune response to environmental allergens. In the pathogenesis of asthma, histamine is one of the important inflammatory mediators released from granules of mast cells. In this study, we evaluated the therapeutic effect of CGJ on a mouse model of ovalbumin (OVA)-induced asthma via the suppression of histamine release. C57BL/6 mice were sensitized by intraperitoneal injection of OVA or a phosphate-buffered saline (PBS) control and then challenged with OVA inhalation. Mice were treated intraperitoneally with either 70% ethanol-extracted CGJ (CGJE) (100 mg/kg/day) or equivalent PBS. Asthma-related inflammation was assessed by bronchoalveolar lavage fluid cell counts and histopathological and immunohistochemical analysis of lung tissues. To elucidate the mechanisms of asthma inhibition by CGJE treatment, we also examined degranulation and histamine release of compound 48/80-induced rat peritoneal mast cells (RPMCs). Treatment with CGJE downregulated the number of eosinophils and monocytes in the lungs of mice challenged with OVA and suppressed histopathological changes, such as eosinophil infiltration, mucus accumulation, goblet cell hyperplasia, and collagen fiber deposits. Moreover, CGJE alleviated compound 48/80-induced mast cell degranulation and histamine release from RPMCs through inhibition of calcium (Ca 2 + ) uptake as well as ear swelling by infiltration of inflammatory cells. These findings demonstrated that CGJE can be used as an antiasthmatic dietary supplements candidate for histamine-mediated asthma.

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Antioxidant and free radical scavenging activity of methanol extract of chungkukjang

Cited by 61 publications

References 31 publications

Nutritional Assessment and Molecular Identification of Microorganisms from Akhuni/Axone: A Soybean Based Fermented Food of Nagaland, India

Nutritional Assessment and Molecular Identification of Microorganisms from Akhuni/Axone: A Soybean Based Fermented Food of Nagaland, India

Evaluation of Nephrotoxic Effects of Aflatoxins on Common Carp (Cyprinus carpio)

CheonggukjangEthanol Extracts Inhibit a Murine Allergic Asthma via Suppression of Mast Cell-Dependent Anaphylactic Reactions

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