Antioxidant and Free Radical Scavenging Capacity of Seed and Shell Essential Oils Extracted from Abrus precatorius (L)

Okoh, Sunday O.; Asekun, Olayinka Taiwo; Familoni, Oluwole B.; Afolayan, A. J.

doi:10.3390/antiox3020278

Cited by 78 publications

(47 citation statements)

References 23 publications

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“…The DPPH assay of the radical scavenging activity was performed according to the procedure modified by Liu et al (), Okoh, Asekun, Familoni, and Afolayan (), and Lee, Lee, Lee, and Cho (). From the methanolic extract of the oil sample to be tested, several oil solutions were prepared at different concentrations (0.0625–1 g/mL) in bottles protected from light, and then 1 mL of each of the oil solutions were mixed with 4 mL of DPPH (40 mg/L) in methanol.…”

Section: Methodsmentioning

confidence: 99%

“…The ABTS assay of the radical scavenging activity of the methanolic extracts of the oil samples was performed by following the standard procedure, as modified by Liu et al () and Okoh et al (). Briefly, ABTS was produced by enabling a 7 mM ABTS stock solution to react with 2.45 mM of potassium persulfate and allowing the mixture to stand in the dark at room temperature for about 16 hr before use.…”

Section: Methodsmentioning

confidence: 99%

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Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Muangrat

Veeraphong

Chantee

2018

J Food Process Preserv

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In this work, the effects of operating parameters, such as drying temperature (60, 75, 90 °C) and press head temperature (60, 75, 90 °C), on oil yields from Sacha inchi (Plukenetia volubilis L.) seeds were studied using a single screw press machine. It is found that non‐dried Sacha inchi samples gave a high oil yield compared to dried samples for all press head temperatures. These Sacha inchi oils contained high content of polyunsaturated fatty acids, mainly α‐linolenic and linoleic acids. The total content of phenolic compounds in these oils ranges from 30.46 to 120.32 mg GAE/100g oil, DPPH IC50 value 317.33 to 663.54 mg/mL, and ABTS IC50 value 215.48 to 301.75 mg/mL. Additionally, these oil samples have peroxide (1.94–2.27 meq O2/kg oil), iodine (102.66–104.05 g I2/100g oil), saponification (182.18–195.11 mg KOH/g oil) and acid (1.94–5.90 mg KOH/g oil) values, as well as the free fatty acid percentages (0.97–2.97%). Practical applications Screw press extraction is a cost‐efficient method, requiring a shorter extraction time than solvent extraction process and leaving no solvent residues in the oil product. Here, a single screw press machine at different press head temperatures was used to extract oil from Sacha inchi seeds. The various Sacha inchi oil extracts had differences in their fatty acid levels. Additionally, the Sacha inchi oil was found to contain total phenolic compounds, which can be potentially used as an alternative source of natural antioxidants in pharmaceutical or food industries.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Muangrat

Veeraphong

Chantee

2018

J Food Process Preserv

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“…The GC/MS quantitative and qualitative analyses of the crude and refined neem oils in our previous report (Okoh, Ahmed, Okoh, & Igwe, 2014), revealed the presence 9 -octadecenoic (oleic) acid (30.42 %), 6 -hexadecenoic acid (11.02 %), palmitic acid (21.51 %), Stearic acid (17.75 %) and methyl octadecanoate (16.88 %) as the dominant compounds. Other important compounds in the crude and the refined oils (NCO, RNO1 and RNO2) were 2-pentanethiol (1.30-5.28 %), 3, 13-octadecedienol (2.50 -2.80 %), 2-dodecenal (0.23-3.59 %) and trans-2-decenal (0.42-2.71 %).…”

Section: Composition Of the Oil Extractedmentioning

confidence: 99%

“…The crude neem oil is however very bitter and further study may be necessary to eliminate or reduce the bitter taste for wider applications (Okoh, Ahmed, Okoh, & Igwe, 2014).There is also scanty information on the refined neem oil as well as the comparative study of the antioxidant capacity of the crude and refined (de-bittered) seed oils in variety of radicals quenching assays. Therefore, this present research was conducted to investigate the in-vitro antioxidant capacity and free radical scavenging activity of the crude seed-oil extracted from A. indica as well as the refined oil.…”

Section: Introductionmentioning

confidence: 99%

“…Oxidative stress has been implicated in the pathogenesis of a variety of inflammatory diseases such as arthritis, stroke, intestinal ischemia, acquired immunodeficiency syndrome (AIDS), hypertension, neurologic diseases e.g., multiple sclerosis, Alzheimer's disease, diabetes, cancers, and atherosclerosis (Sachdev, & Davies, 2008;Mahmood, Soheila, & Saeid, 2008;Saikat, Chakraborty, Sridhar, Reddy, & Biplab, 2010;Mimica-Dukic, Dušan, Slavenko, Dragana, & Branka, 2010;Okoh, Asekun, Familoni, & Afolayan, 2014). Plants contain antioxidant compounds that function as free radical scavengers, reducing agents and quenchers of singlet oxygen formation.…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant and Free Radical Scavenging Capacity of Crude and Refined Oil Extracted From Azadirachta indica A. Juss.

Okoh¹,

Oyewole²,

Ishola³

et al. 2015

IJB

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Naturally nutritive and non-nutritive occurring antioxidants have been proven potent and safe for management of variety of diseases. This study investigated the antioxidant and free radical scavenging capacity of crude and refined Azadirachta indica (Neem tree) oil. The neem crude oil (NCO) was extracted from the seeds by mechanical press and degummed. The neem oil was de-pigmented with activated charcoal, and fractionated with silica gel in a capillary column. The ability of the oils to act as hydrogen/electrons donor were determined in-vitro using 2, 2-dipphenyl-1-picrylhydrazyl (DPPH), 2, 2-azinobis -(3-ethylbenzothiazolin -6-sulfonic acid) diammonium salt (ABTS), lipid peroxyl (LP) and nitric oxide (NO) radicals scavenging assays, at different extract concentrations (0.1, 0.2, 0.3 and 0.4 mg/mL). The IC 50 of the NCO oil (1.50 ± 0.10 mg/mL) showed that antioxidant activity is comparable to vitamin C and β-carotene (1.60 ± 0.10 and 1.27 ± 0.12 mg/mL respectively) in scavenging DPPH radical. The crude neem oil exhibited superior activity against NO radical, than the refined oil and vitamin C. Generally, in the four antioxidant assays, a significant correlation existed between concentrations of the oils and percentage inhibition of the four different radicals. GC/MS analyses identified monounsaturated and saturated fatty acids, aldehydes and pentanethiol as the major compounds in the oils, these may account for their antioxidant capacity.

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Plant‐Inspired Multifunctional Bioadhesives with Self‐Healing Adhesion Strength to Promote Wound Healing

Zhang

Martín-Saldaña

et al. 2022

Adv Materials Inter

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Bioadhesives are revolutionizing wound closure procedures. However, traditional bioadhesives lack functions to promote wound healing with a higher wound dehiscence rate than those treated with sutures. As a result, creating multifunctional bioadhesives to improve wound healing and facilitate wound care is extremely desirable in clinical settings. This study develops a series of multifunctional bioadhesives using succinic anhydride‐modified hyaluronic acid (HASA) and plant‐derived tannic acid (TA) with centrifuging and freeze‐drying. By varying the ratio of HASA to TA, HASATA 1:2, 1:7, and 1:14 are fabricated with tunable adhesive strength from 39.6 ± 8.2 to 63.0 ± 12.0 kPa. The bioadhesives exhibit self‐healing adhesive strength due to the reversible cohesion network developed by HASA and TA, enabling 25 to 50 times repeated wound closure. The animal studies reveal that the developed bioadhesives accelerate wound healing in the first week with a higher collagen content, more M2 macrophage upregulation and less oxidative stress. Moreover, the plant‐derived TA endows the bioadhesives with antioxidant properties against four kinds of free radicals, and antibacterial activity against both gram positive and negative bacteria. Altogether, these bioadhesives may open new avenues for noninvasive wound closure in the clinical setting.

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Antioxidant and Free Radical Scavenging Capacity of Seed and Shell Essential Oils Extracted from Abrus precatorius (L)

Cited by 78 publications

References 23 publications

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Antioxidant and Free Radical Scavenging Capacity of Crude and Refined Oil Extracted From Azadirachta indica A. Juss.

Plant‐Inspired Multifunctional Bioadhesives with Self‐Healing Adhesion Strength to Promote Wound Healing

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