Antioxidant and nitric oxide inhibition activities of selected Malay traditional vegetables

Abas, Faridah; Lajis, Nordin Hj; Israf, Daud Ahmad; Khozirah, S.; Kalsom, Y. Umi

doi:10.1016/j.foodchem.2005.01.034

Cited by 175 publications

(142 citation statements)

References 36 publications

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“…The experiment was performed in six replicates, and the cells were incubated for 17 h at 37 • C, 5% CO 2 in a humidified incubator. The controls used in this experiment were curcumin as the positive control, blank medium, while the other two controls are the cells cultured in medium only and that cultured in the medium containing triggering agents with 0.4% DMSO [32].…”

Section: Nitric Oxide Inhibitory Activitymentioning

confidence: 99%

“…The percentage of inhibition was calculated for all samples. Fresh culture medium was used as a blank in every experiment [32].…”

Section: Measurement Of Nitritementioning

confidence: 99%

“…The cells were incubated at 37 • C in 5% CO 2 for 4 h. The absorbance was read at 570 nm. The absorbance of formazan salt in the control (untreated cells) was taken as 100% viability, where the percentages of dead cells were calculated in comparison to the control group [32].…”

Section: Cell Viabilitymentioning

confidence: 99%

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Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin

et al. 2016

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This study was aimed at examining the variations in the metabolite constituents of the different Ajwa grades and farm origins. It is also targeted at establishing the correlations between the metabolite contents and the grades and further to the nitric oxide (NO) inhibitory activity. Identification of the metabolites was generated using 1 H-NMR spectroscopy metabolomics analyses utilizing multivariate methods. The NO inhibitory activity was determined using a Griess assay. Multivariate data analysis, for both supervised and unsupervised approaches, showed clusters among different grades of Ajwa dates obtained from different farms. The compounds that contribute towards the observed separation between Ajwa samples were suggested to be phenolic compounds, ascorbic acid and phenylalanine. Ajwa dates were shown to have different metabolite compositions and exhibited a wide range of NO inhibitory activity. It is also revealed that Ajwa Grade 1 from the al-Aliah farm exhibited more than 90% NO inhibitory activity compared to the other grades and origins. Phenolic compounds were among the compounds that played a role towards the greater capacity of NO inhibitory activity shown by Ajwa Grade 1 from the al-Aliah farm.

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Section: Nitric Oxide Inhibitory Activitymentioning

confidence: 99%

“…The percentage of inhibition was calculated for all samples. Fresh culture medium was used as a blank in every experiment [32].…”

Section: Measurement Of Nitritementioning

confidence: 99%

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Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin

et al. 2016

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“…The biological activity of these quinoline derivatives depends not only on the bicyclic hetero-aromatic pharmacophore but also on the nature of the peripheral substituent and their spatial relationship. They also exhibit antimalarial 2 , antitumor 3 , antioxidant 4 , antileishmanial 5 and antiplatelet activities 6 . In addition they function as pharmacologically active synthetic compounds 7 such as DNA binding capabilities 8 and DNA-intercalating carrier 9 .…”

Section: Introductionmentioning

confidence: 99%

Synthesis of certain novel 4H-pyrano[3,2-h]quinoline derivatives

El‐Agrody¹,

Al-Ghamdi²

2011

Arkivoc

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“…Ocimum basilicum (Lamenaceae) is a well known aromatic and medicinal plant, which attracted great attention in the ancient system of Indian medicine for its use in various ailments such as muscle cramps, pain, insecticidal, antiulcer, anti-inflammatory, diabetes and respiratory tract problems [20][21][22][23][24] . Traditionally, the essential oil of Ocimum basilicum was used as anti-inflammatory, antiseptic, and gastrointesinal protective medicine 25, 26 .…”

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confidence: 99%

Microwave Assisted Synthesis and Characterization of Silver Nanoparticles Using Ocimumbasilicum and its Anti-Inflammatory Activity against Human Blood Cells

2016

IJSR

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The present investigation was to synthesis the nanoparticles by using the medicinal plant Ocimum basilicum leaf extract and silver nitrate solution. The synthesized silver nanoparticles were analyzed by UV Spectroscopy (UV-Vis), Transmission Electron Microscopy (TEM), X-ray diffraction spectroscopy (XRD) and Fourier transform infrared spectroscopy (FTIR). The particle is found to have an average size of 14.6 nm& 13.8nm by XRD and TEM analysis respectively. The silver nanoparticles were synthesized by microwave assisted method, which was found to yield nanoparticles rapidly and easily. Further, these nanoparticles were found to exhibit AgNPs, which may also be efficiently employed in Anti-inflammatory activity of pharmaceutical research to obtain better result of plant as shown by our study. The anti-inflammatory activity of silver nanoparticles was tested and confirmed against human blood cells. Hence, the present research aims to open new avenues for the improvement of medicinal uses with the synthesis of silver nanoparticles by using Ocimum basilicum leaf extract for various ailments and to bring the anti-inflammatory medicinal plant to the scientist's notice, to educate awareness and add values to the resource.

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Antioxidant and nitric oxide inhibition activities of selected Malay traditional vegetables

Cited by 175 publications

References 36 publications

Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin

Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin

Synthesis of certain novel 4H-pyrano[3,2-h]quinoline derivatives

Microwave Assisted Synthesis and Characterization of Silver Nanoparticles Using Ocimumbasilicum and its Anti-Inflammatory Activity against Human Blood Cells

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