2024
DOI: 10.4314/njbmb.v38i4.5
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Antioxidant and protective activities of aqueous Theobroma cacao seed extract against aluminium-induced hippocampal toxicity in Wistar rats

Anita A. Okhah,
Adaze B. Enogieru

Abstract: Aluminium (Al) is a known toxic metal linked to oxidative damage and neurodegeneration. Hence, the antioxidant and neuroprotective effects of aqueous Theobroma cacao seed extract (CO) in aluminium chloride-exposed Wistar rats was examined. The study consisted of six (6) groups containing six (6) Wistar rats each. Group A (Control) received 1 ml of distilled water/day. Group B (Al) received 100 mg/kg body weight (BW) of Al only. Group C received 250 mg/kg BW/day of CO and 100 mg/kg BW of Al. Group D received 50… Show more

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