Antioxidant, antimicrobial, and photocatalytic activity of green synthesized ZnO-NPs from Myrica esculenta fruits extract

Lal, Sohan; Verma, Ritesh; Chauhan, Ankush; Dhatwalia, Jyoti; Guleria, Ishita; Ghotekar, Suresh; Thakur, Shabnam; Mansi, Kumari; Kumar, Rajesh; Kumari, Amita; Kumar, Pushpendra

doi:10.1016/j.inoche.2022.109518

Cited by 45 publications

(20 citation statements)

References 78 publications

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“…The lower IC 50 value of ZC NPs indicates a stronger DPPH scavenging ability. Moreover, bimetallic ZC NPs also showed enhanced anti-DPPH free radical scavenging activity than monometallic CuO and ZnO NPs, which were reported in previous works. , These may be due to the occurrence of free charge transferring from the containing CuO and ZnO NPs to the DPPH radical . Therefore, the biosynthesized ZC NPs from the A.…”

Section: Resultssupporting

confidence: 59%

Biosynthesis of Artemisia abyssinica Leaf Extract-Mediated Bimetallic ZnO–CuO Nanoparticles: Antioxidant, Anticancer, and Molecular Docking Studies

Orshiso,

Zereffa,

Murthy

et al. 2023

ACS Omega

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Currently, plant extract-mediated synthesized metal oxide nanoparticles (MO NPs) have played a substantial role in biological applications. Hence, this study focused on the eco-benign one-pot synthesis of bimetallic ZnO−CuO nanoparticles (ZC NPs) using the leaf extract of Artemisia abyssinica (LEAA) and evaluations of their anticancer, antioxidant, and molecular binding efficacy. The optical absorption peak at 380 nm from UV−visible (UV−vis) analysis revealed the formation of ZC NPs. X-ray diffraction (XRD) results revealed the fabrication of mixed-phase crystals with hexagonal and monoclinic structures of ZC NPs with an average crystallite size of 14 nm. Moreover, the biosynthesis of ZC NPs with a spherical morphology and an average particle size of 13.09 nm was confirmed by scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and transmission electron microscopy (TEM) results. Fourier transform infrared (FTIR) and thermogravimetric analysis (TGA/DTA) spectroscopy confirmed the involvement of functional groups from LEAA during the synthesis of ZC NPs. ZC NPs have exhibited the ferric ion reducing power (FRAP) with an absorbance of 1.826 ± 0.00 at 200 μg/ mL and DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical scavenging activity of 95.71 ± 0.02% at 200 μg/mL with an IC50 value of 3.28 μg/mL. Moreover, ZC NPs had shown a promising in vitro anticancer activity of 89.20 ± 0.038 at 500 μg/mL with an IC50 value of 33.12 μg/mL against breast cancer (MCF-7) cell lines. Likewise, ZC NPs have shown strong binding affinity (−8.50 kcal/mol) against estrogen receptor α (ERα) in molecular docking simulations. These findings suggested that the biosynthesized ZC NPs could be used as promising antioxidant and anticancer drug candidates, particularly for breast cancer ailments. However, the in vivo cytotoxicity test will be recommended to ensure further use of ZC NPs.

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Section: Resultssupporting

confidence: 59%

Biosynthesis of Artemisia abyssinica Leaf Extract-Mediated Bimetallic ZnO–CuO Nanoparticles: Antioxidant, Anticancer, and Molecular Docking Studies

Orshiso,

Zereffa,

Murthy

et al. 2023

ACS Omega

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“…Another report in which a comparable IC 50 value between the standard ascorbic acid used as a positive control (4.96 mg ml −1 ) and a ZnO nanomaterials (8.99 mg ml −1 ) (mediated using Dovyalis caffra) has been made in literature [43]. Moreover, an IC 50 of 182.63 μg ml −1 have been documented in literature for the scavenging activities of ZnO mediated using fruit extract of Myrica esculenta [5]. Hence, our study here shows that the prepared ZnO nanomaterials have the potential to be added to the design of active food packaging, consistent with recent literature results showing that the activity of produced ZnO nanomaterials and ascorbic acid is equivalent.…”

Section: Antioxidant Activities (Abts + Dpph Radical Scavenging Acti...mentioning

confidence: 84%

“…Comparable concentration-dependent behaviour has been reported in other studies involving different biological sources for ZnO nanomaterial synthesis. For instance, good reducing power has been observed with ZnO nanomaterials prepared using Saccharomyces cerevisiae [48], Spinacia oleraceae [65], and Myrica esculenta [5]. The crucial role of phenolic content in the biosynthesis of nanomaterials, as shown in the TPC analysis (in figure 3), may have accounted for the observed FRAP activities.…”

Section: Antioxidant Activities (Abts + Dpph Radical Scavenging Acti...mentioning

confidence: 90%

“…However, the quest to maximize food production has significantly increased the generation of food waste (FW) [4]. Current estimates suggest that approximately 1.3 billion tonnes of FW are generated worldwide per year, a figure projected to double to 2.6 billion tonnes by 2025 [5], with households responsible for 42% of this waste, while industries that manufacture food and provide food services contribute 39% and 14%, respectively [6]. A large volume of FWs that are not utilized (i.e., for animal feed) are mostly thrown into municipal landfills where they generate greenhouse gas (GHG) and methane that may result in severe environmental impact [7].…”

Section: Introductionmentioning

confidence: 99%

“…Nevertheless, numerous phenolic compounds have been linked to the bioreduction of metal salt ions into 0 valence metal nanomaterials [19]. Thus, these bioactive compounds are fundamental reducing and capping agents [5,20]. Therefore, since many food wastes contain a significant number of bioactive compounds, they have been employed in the bio-fabrication of metal and metal oxide nanomaterials such as Ag, Au, CuO, MgO, and ZnO due to safe handling and availability [16,21].…”

Section: Introductionmentioning

confidence: 99%

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Valorisation of pomegranate processing waste for the synthesis of ZnO nanoparticles: antioxidant and antimicrobial properties against food pathogens

Leta,

Adeyemi,

Fawole

2023

Mater. Res. Express

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The sustainable management of food waste is a pressing concern, with fruit waste valorisation emerging as a viable strategy to address this challenge. This study investigated the potential of pomegranate peel waste (PPW) and pomegranate seed waste (PSW) as mediating agents for the biosynthesis of zinc oxide (ZnO) nanoparticles (NPs); ZnO-PPW and ZnO-PSW, respectively, for potential utilization as additives in various polymer matrices for food packaging materials. The resulting physicochemical characteristics were ascertained using Ultraviolet visible spectroscopy (UV–vis), x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), x-ray diffraction (XRD), Scanning electron microscope (SEM) and Energy Dispersive x-Ray Analysis (EDX). The obtained indexed diffractogram from the XRD analysis for both ZnO-PPW and ZnO-PSW confirmed the wurtzite crystalline structure of ZnO NPs. The observed morphology from the TEM and SEM analysis showed a similar spherical shaped structure, with agglomerations. However, ZnO-PSW, had a smaller size (58 nm) in comparison to ZnO-PPW (59 nm). Total phenolic content (TPC) for ZnO-PPW and ZnO-PSW ranged from 16.87–54.4 μg GAE/g DM, respectively. Also, the estimated minimum inhibitory concentration at 50% (IC50) for both DPPH and ABTS are 2.97 and 2.57 mg ml−1 for ZnO-PPW; and 3.43 and 3.33 mg ml−1 for ZnO-PSW, respectively. Moreover, due to its smaller size, ZnO-PSW demonstrated superior antimicrobial activity against five foodborne microorganisms. These findings suggest that pomegranate waste derived ZnO NPs could be beneficial for developing active food packaging materials.

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Rosemary‐Mediated Green Synthesis of ZnO Nanoparticles and their Integration into Hydrogel Matrices: Evaluating Effects on Wheat Growth and Antibacterial Properties

Uysal,

Görkem Doğaroğlu,

Çaylali

et al. 2024

Global Challenges

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In this study, the impact of zinc oxide nanoparticles (ZnO‐NPs) generated using rosemary extract, synthesized using environmentally friendly processes and integrated into a cross‐linked polymer matrix, on growth performance of wheat is evaluated. Rosemary extract used as coating, stabilizing, and reducing agents in this green synthesis method. Fourier transform infrared spectroscopy analyses demonstrated the presence of phytochemical constituents of the plant extract that served as capping agents during the synthesis process. The nanoparticles are sprayed to the plant leaves. The effects of nanoparticles within the hydrogel on plant development are compared with the effects of nanoparticles in suspension. The percentage of seed germination is unaffected by either rosemary‐ or raw‐ZnO‐NPs; however, the root and shoot elongation are considerably impacted by the nanoparticle treatments. The threshold concentrations are determined as 3000 mg L−1 for rosemary‐ZnO‐NPs and 2000 mg L−1 for raw‐ZnO‐NPs. Additionally, antibacterial test results showed that the activity level on Escherichia coli is higher for rosemary‐ZnO‐NPs compared to raw‐ZnO‐NPs. The results of this research may provide guidance on how green synthesis methods and the use of nanoparticle‐hydrogel composites in plant breeding can be used in future agricultural applications. This can be considered an important step in terms of agricultural innovations and sustainability.

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Antioxidant, antimicrobial, and photocatalytic activity of green synthesized ZnO-NPs from Myrica esculenta fruits extract

Cited by 45 publications

References 78 publications

Biosynthesis of Artemisia abyssinica Leaf Extract-Mediated Bimetallic ZnO–CuO Nanoparticles: Antioxidant, Anticancer, and Molecular Docking Studies

Biosynthesis of Artemisia abyssinica Leaf Extract-Mediated Bimetallic ZnO–CuO Nanoparticles: Antioxidant, Anticancer, and Molecular Docking Studies

Valorisation of pomegranate processing waste for the synthesis of ZnO nanoparticles: antioxidant and antimicrobial properties against food pathogens

Rosemary‐Mediated Green Synthesis of ZnO Nanoparticles and their Integration into Hydrogel Matrices: Evaluating Effects on Wheat Growth and Antibacterial Properties

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