Antioxidant, Antimicrobial and Phytochemical Study of Different Solvent Extracts of Fruits of Terminalia bellerica (Gaertn.) Roxb., from Dibrugarh, Assam

Abstract

Terminalia bellerica (Gaertn.) Roxb. is widely cultivated plant due to its significance use as traditional medicine. The fruits of the plant were collected from Dibrugarh district of Assam, India. The present study aimed to evaluate the phytochemical, antioxidant and antimicrobial activity of different solvent extracts of the fruits of Terminalia bellerica. Antioxidant and phytochemical analysis were carried out using standard methods and the results revealed the presence of tannins, flavonoids, phenols and glycosides in the fruit sample. Among the solvent used for the extraction process, Ethyl acetate extract recorded the highest phenol content (6.56±0.004mgCE/gm dried body weight) and antioxidant activity (67.00± 0.12%) against DPPH. Similarly, ethyl acetate extract recorded the highest (22±1mm) inhibition against B. subtilis compared to Chloramphenicol (30mcg) and Clotrimazole (10mcg). It is concluded that the ethyl acetate extract of the fruits Terminelia bellerica yielded the best results and more efficacious in terms of antimicrobial activity which makes it more useful in new drug development.