Antioxidant, antimicrobial andantimutagenic potencial of the Myrtuscomunis L.

Bugarin, Dušan

doi:10.2298/ns20100608bugarin

Cited by 1 publication

(2 citation statements)

References 67 publications

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“…(Vinson et al, 2001;Bakova et al, 2021;Snoussi et al, 2021;Yaghoobi et al, 2022). In generally, our results agree with those previously published, both in terms of amount and composition of myrtle phenolic compounds (Bugarin, 2010;Amensour et al, 2010;Sumbul et al, 2011;Babou et al, 2016). Considering the complexity and relevance of antioxidant assessments, especially in the case of complex mixtures, here we applied seven tests representing different mechanisms.…”

Section: Discussionsupporting

confidence: 90%

“…Ellagic acid and its derivatives were also detected. The samples did not differ significantly in qualitative composition (Bugarin, 2010). Regarding TFC, one must bear in mind that the applied AlCl3 colorimetric test does not measure flavonoids without characteristic chelating functional groups for Al 3+ binding, e.g., flavanones and flavanonols (Vinson et al, 2001).…”

Section: Antioxidant Activity (Aoa)mentioning

confidence: 97%

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Bioactivity of Myrtus communis from the Montenegro coastline

Bugarin,

Mitic-Culafic,

Svircev

et al. 2024

BLACPMA

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Although numerous studies have demonstrated the biomedical potential of Myrtus communisL., (Myrtaceae) data on myrtle from Montenegro are scarce. To evaluate antioxidant, antimutagenic and antibacterial activity of myrtle methanolic extracts. Antioxidant activity was evaluated by measuring free radicals scavenging activity, reducing power and enzyme inhibition. The strongest scavenging activity was towards DPPH radical (2,2-diphenyl-1-picrylhydrazyl) (IC501.69-2.25 mg/mL) and superoxide anion (IC500.56 to 0.88 mg/mL), followed by high reducing power (428-472 mgAA/g.DE) and inhibition of XOD (IC500.308-0.6261mg/mL). Antimutagenic activity was evaluated in reverse mutation assays with Escherichia coliWP2 oxyR mutant IC202 and deficient in the induction of antioxidant enzymes. The myrtle extracts strongly inhibited mutagenesis induced by t-BOOH, reaching 70% at the highest concentration applied. Antimicrobial activity was examined on eight different bacterial strains. Gram-positive bacteria, S. epidermis, S. aureusand M. flavus demonstrated the highest sensitivity towards extracts (MICs 4.5-9 mg/mL), but significantly lower towards essential oil (MIC 0.42-3.32 mg/mL).

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