Antioxidant, antimutagenic and antibacterial activities of curcumin-β-diglucoside

Antimicrobial Activity of Curcumin-Loaded Myristic Acid Microemulsions against <i>Staphylococcus epidermidis</i>

“…Recently curcumin and its derivatives exhibited antibacterial activity against Staphylococcus aureus, E. coli, Bacillus cereus, and Yersinia enterocolitica. 19) The antibacterial activity of curcumin is due to inhibition of the cytokinetic Z-ring assembly from FtsZ protofilaments, which playing critical roles in bacterial cytokinesis. 20) Fatty acids inhibit gram-positive cocci by disrupting the electron transport chain and oxidative phosphorylation of the bacteria.…”

“…For example, the combination of 5% azelaic acid and 2% clindamycin is used to clinically treat acne vulgaris. 19) The cellular target of myristic acid is the electron transport chain and oxidative phosphorylation.…”

Direct chemical grafted curcumin on halloysite nanotubes as dual-responsive prodrug for pharmacological applications

“…In particular, the antioxidant properties are attributed to the phenolic OH groups and the CH 2 group of the ␤-diketone moiety, which is in equilibrium with its enol tautomer [57][58][59]. Curcumin has been shown to inhibit lipid peroxidation and to manifest free radical-scavenging activity, in particular toward oxygen and nitrogen-centered free radicals.…”

Activation of Nuclear Factor Erythroid 2-Related Factor 2 Cytoprotective Signaling by Curcumin Protect Primary Spinal Cord Astrocytes against Oxidative Toxicity

“…[4][5][6][7][8] Deficiency of antioxidantive function in astrocyte has been implicated in many neurodegenerative processes. [9][10][11][12][13][14][15] Neuronal loss occurred in spinal cord, such as amyotrophic lateral sclerosis (ALS) and spinalmuscularatrophy (SMA), has been attributed to the deterioration of the ability of spinal cord astrocytes to support neurons. 16,17) On the other hand, compromised astrocytes function may increase the neuron's susceptibility to oxidative stress.…”